Rhabdomyosarcoma Embryonal: daaweynta, saadaal

Rhabdomyosarcoma loola jeedaa nooc ka mid ah sarcoma - kansarka unugyada jilicsan, lafta ama unugyo. burada u badan tahay in ay ka dhacdo muruqyada ku lifaaqan lafaha. Rhabdomyosarcoma - kansar asal ahaan in murqaha lafaha. Waxay bilaabaan in qayb kasta oo ka mid ah jirka ama meelo dhowr ah.

Microscopically rhabdomyosarcoma ee dadka waaweyn ayaa qaab unugyada elongated ama soo koobay yaab leh. dabeecad More burada ah ee carruurnimada.

noocyada rhabdomyosarcoma

Rhabdomyosarcoma ee qaab-dhismeedka gudaha u qaybsan yihiin nooc:

1. unugyada rhabdomyosarcoma Embryonal ka kooban wareega iyo fusiform kuwaas oo baaritaan cytoplasm muujinaysaa a Kormooyin gaadhya ama transverse. Noocan ah rhabdomyosarcoma dhacaan marar badan. Waxay u muuqataa rhabdomyosarcoma embryonal in carruurta iyo qaan-gaarayaan. Waxay ku taalaa qoorta ama madaxa, on xubnaha taranka, in bacaraarka. dareen The of burooyinka in dawaynta ilaysku, laakiin waa mid u nugul noqoshada deg deg ah.

2. rhabdomyosarcoma Alveolar ka kooban yahay koox ka mid ah unugyada wareega iyo gadood, kuwaas oo ku hareereysan septa of unugyo. Wixii noocan ah burooyin lagu gartaa muuqaalka on lugaha ama gacmaha, caloosha, naaska, futada ama xubnaha taranka. Inta badan waxaa laga heli karaa dhallinyarada iyo dadka waaweyn ee addimmada waxay aad. Saadaal waa miskiin.

3. Qaab dhismeedka rhabdomyosarcoma pleomorphic - dunmiiqa-qaabeeya, qoofalan-sida, unugyada star-qaabeeya polymorphic burada oo u muuqan kara on lugaha ama gacmaha dadka. Sida caadiga ah, koritaanka rhabdomyosarcoma si deg deg ah ay dhacdo iyo ma keento xanuunka iyo xanuunada functional. Waxay dhacdaa xididdada oo kaliya. Waxay inta badan ku koraan iyada oo maqaarka iyo daboolay nabaro, la xirrira exophytic, buro dhiig.

sababaha halista

Waxaa ka mid ah arrimaha deegaanka helay sida, in la kordhiyo itimaalka dhacdada burada this. Arrintani waxay ka duwan inta badan kansarka rhabdomyosarcoma.

Sababo la xaqiiqada ah in si sax ah waxaa lama yaqaan sababaha horumarka buro, ma siin karno talo kasta oo ka fogaanaya in laisla. Si kastaba ha ahaatee, waa in aan ku haay maanka in la daaweyn ku filan bukaannada qaba rhabdomyosarcoma mararka qaarkood in gebi ahaanba la daaweyn karaa.

sababaha halista muuqaalka kore ee rhabdomyosarcoma SNMna waa cudurro hiddo go'an sida:

1. Li-Fraumeni syndrome waa cudur dhif ah kaas oo dhaxlay sifo, dhaawac hiddo markii la waayay hal waalid si ay u soo noqnoqoshada sare noocyada kala duwan buro kacay. Dhaxlay in cudurada this cayimayo of falcelinta unugyada burada markii si weyn kordhaya suurtagalka la isugu gudbiyo horumarinta burooyinka da'da hore (30 sano).

2. halsiata nooca ugu horeysay - cudurada ugu badan dhaxlo oo keena muuqaalka kore ee cabista in kansar.

3. Syndrome Beckwith-Wiedemann - cudurada, taas oo ah waxa lagu gartaa macrosomia, macroglossia iyo omphalocele. Waxaa sidoo kale ciladaha muuqata in reer derbiga hore ee caloosha, Sheelada, hypoglycaemia dhalaanka, kala muruqyada ka qabo.

4. Costello syndrome - cudur dhif ah, taas oo ah waxa lagu gartaa curyaanimo dhasho: dhimaal koritaanka, sifooyinka wajiga aan dhab ahayn, isbedel maqaarka.

5. Noonan ee syndrome - disorder ah hidde lagu gartaa dherer gaaban kaas oo wixii khaldama iyo horumarinta degaaankaaga. Waxaa dhici kara in qoyska ama mid ka mid ah xubnihiisa.

Dhallaanka lahaa miisaanka dhalashada iyo koboca, in ka badan kuwa kale, khatarta ah in rhabdomyosarcoma embryonal. Sida caadiga ah, si kastaba ha ahaatee, sababaha rhabdomyosarcoma embryonal la aqoon. Calaamad A cudurka waa muuqaalka kore ee buro noqday iyo aad u badan.

calaamadaha

Symptomatology cudurka kansarka waxaa lagu go'aamiyaa. Loo baahan yahay isla markiiba la tasho dhakhtar haddii carruur ah ayaa ku qoran calaamadaha kansarka:

• barar ama barar, sii kordhaysa ee size ama aan marayay, mararka daran;
• indhaha ferjiga;
• madax xanuun daran;
• dhibaato ku saxaroodaan iyo kaadida;
• dhiigga kaadida;
• dhiigbaxa dabada, sanka iyo dhuunta.

Baadhista xanuunada

Si aad u taariikhda, waxay horumariyeen hababka lagu ogaanayo rhabdomyosarcoma ilaa astaamaha ugu horeeyay ee ilqabatinka.

Calaamadaha ugu horreeya ee kansarka - bararka ee xaafaddaada ama induration, ma keeno dhibaatooyin marka hore ama xanuun. Cudurkaan waa mid caan ku rhabdomyosarcoma, gacmaha, lugaha iyo jir.

Haddii buro waa teelteel ah caloosha ama miskaha waxay keeni kartaa calool xanuun, matag ama calool. Waxaa rhabdomyosarcoma embryonal ee bannaan ee retroperitoneal. More dhif ah, horumarinta ee mareenka biliary, rhabdomyosarcoma sababa cagaarshow.

Haddii uu jiro shaki ah buro this, waxaa lagama maarmaan ah si ay u qabtaan biopsy ah, oo u sheeg doonaa nooca rhabdomyosarcoma asalkiisu ka soo jeedo.

Xaaladaha intooda badan, rhabdomyosarcoma baxdo meelaha si fudud loo ogaan karo, tusaale ahaan, dalool sanka ama ka baxsan bu'da. Haddii indhaha ferjiga, ama dheecaanka sanka ka muuqan, waa inaad isla markiiba la tasho dhakhtar la buro looga shakisan yahay in lagu ogaan marxalad hore ee ay horumarka. In kiiska halkaas oo rhabdomyosarcoma u muuqataa on dusha sare ee jidhka, waxaa si fudud u ogaan oo aan baaritaan buuxa. Tani waxa loogu yeero rhabdomyosarcoma embryonal unug jilicsan.

In 30% bukaannada qaba rhabdomyosarcoma embryonal jira marxalad hore marka la gebi ahaanba saari karo. Laakiin tirada ugu badan ee dadka bukaanka ah Caddaynay baaritaanka ayaa muujinaya metastases yar, daaweynta taas oo u baahan joogitaanka chemotherapy.

rhabdomyosarcoma Embryonal, kuwaas oo ku taala agagaarka xiniin inta badan soo saaray in carruurta yar yar iyo ka helay waalidka ilmaha marka maydhayeen. Haddii burooyin ka dhaca marinka kaadida, waxay keeni dhib in la kaadinayo ama dheecaan dhiig leh - calaamadaha aan la iska indho tiri karin.

stage burada

1. Tallaabada ugu horreysa. buro waxay noqon kartaa size kasta, laakiin waxa ay weli faafin in qanjidhada sameeya habka iyo waxa uu ku yaalaa mid ka mid ah meelaha prognostically wanaagsan ee jidhka:

- indhaha ama meel periocular;

- madaxa iyo qoorta (marka laga reebo kuwa nudaha unugyada in maskaxda iyo meelaha laf-dhabarta);

- bile marinnada iyo xameetida,

- in ilmo-galeenka ama xiniinyaha.

Meelaha ka baxsan ku qoran, waxaa loo arkaa meelaha allifey.

2. Heerka labaad. Barar ama waa mid ka mid ah goobaha allifey (zones oo la la'yahay ee wanaagsan ee). size buro ka yar tahay 5 cm oo ayan sii faafin in qanjidhada uu ka dhacay.

3. Tallaabada saddexaad. buro waxay ku taalaa meel colaadeed, iyo kulmi mid ka mid ah shuruudaha soo socda:

- size ee burada ka yar 5 cm, oo taasna waxaa lagu faafin ka badan qanjidhada soo socda;

- burada waa ka badan 5 cm, oo ay jirto halista ah in ay ku faafi doontaa Guntin lymph ee kuugu dhow.

4. Heerka afaraad. size buro waxay noqon kartaa wax, oo waxaa la faafin in qanjidhada soo socda. Waxaa uu ahaa faafinta kansarka meelaha fog ee jirka.

kooxaha halista

koox loo xilsaaray halis bukaanka go'aamiso suurtagalnimada soo laabto rhabdomyosarcoma. Canug kasta oo daaweynta ka rhabdomyosarcoma embryonal helo, waa in ay helaan chemotherapy dheeraad ah si ay u noqdaan suurtagalnimada yar ee soo noq-buro. View daroogada anticancer, qiyaasta iyo tirada fadhiyada - Waxaas oo dhan waxaa lagu go'aamiyaa halista in ilmo kasta gudbiyo - low, dhexe ama sare.

fursadaha daaweynta

Bukaanka qaba rhabdomyosarcoma embryonal waa la daaweyn karaa siyaabo kala duwan.
Daaweynta ku lug burooyinka halista ah hababka kala gooni ah oo waxaa loo arkaa inay dhaqanka. farsamooyinka kale ee ka yar tahay tijaabo. tijaabo waxay billaabeen inay si loo hagaajiyo hababka hadda jira ee daaweynta ama kordhinta cadadka xogta ka mid ah hababka cusub ee daaweynta bukaanada qaba rhabdomyosarcoma. Haddii iyadoo ay sabab u tijaabo, waxa ay u muuqataa in hababka cusub ee daaweynta waa ay ka sareeyaan dhaqanka, daaweynta cusub galaa category ee dhaqanka.

Tan iyo burooyinka halista ah u muuqdaan in ay u muuqdaan in meelo kala duwan ee jirka, waxay khusaysaa tiro badan oo ah daawaynta. Daaweynta rhabdomyosarcoma carruurta by Oncologist carruurta la kormeerayo.

Waxaa ka mid ah hababka daaweynta, waxaa jira qaar ka mid ah oo keeni kara waxyeelo, xataa marka daaweynta maray tan iyo waqti dheer.

qalliinka

Habka qalliinka, ama ka saarida burada, waxaa si balaadhan looga isticmaalaa in lagu daaweeyo rhabdomyosarcoma. Howlgalkan waxuu waxaa lagu magacaabaa "excision degaanka ballaaran". faragelinta Tani waa qayb ka mid ah burada iyo unugyada ku wareegsan wada saar la qanjidhada in sidoo kale saamayn ku rhabdomyosarcoma. Daaweynta mararka qaar waa in ay sameeyaan dhowr hawlgallo. Go'aanka ku saabsan magacaabidda hawlgalka oo ay ku xiran tahay nooca arrimaha soo socda:

- meel goobta asalka ah ee burada,

- wax kasta oo ilmahaagu hawlaha jidhka by burada saameeyeen,

- jawaab buro in radiotherapy ama chemotherapy, taas oo loo isticmaali karaa oo ku salaysan mudnaanta.

Inta badan saarida carruurta ee mugga oo dhan burada by qaliin suurtogal ma aha.

rhabdomyosarcoma unug jilicsan Embryonal u egtahay in lagu sameeyay meelo kala duwan ee jidhka, kuwaasoo mid walba uu u baahan yahay ay hawlgal gaar ah. qalliin ayaa la tilmaamay in ay dhacdo xubnaha taranka ama indhaha rhabdomyosarcoma, haddii biopsy xaqiijiyay cudurka. Qaliinka ka hor waxaa lagu qori karaa in ay chemotherapy ama radiotherapy si loo yareeyo burooyin waaweyn, taas oo aan la shaqeeya kartaa, si ay u fududeeyaan hawsha ay ka saareen kansarka.

Xitaa haddii dhakhtarka aan ka saari kara buro oo dhan, bukaanka dhamaadka hawlgalka waa in lagu qaado chemotherapy si loo xakameeyo unugyada kansarka in ay noolaadaan. Oo ay la socdaan chemotherapy, Dawaynta ilayska waxaa loo isticmaalaa. Daaweynta golleeyahay in lagu yareeyo halista ah ee cudurku ku soo laabto waxaa lagu magacaabaa therapy Curiyaha taageerada.

Dawaynta ilayska

Iyada oo daweynta noocan ah loo isticmaalo X-ray ama shucaaca kale. Dawaynta ilayska si toos ah ugu wax, inay dilaan unugyada burada ama si ay u joojiyaan koritaanka ay. Its codsiga in daawo helay laba siyaabood oo radiotherapy - dibadda iyo gudaha.

Dibadda isticmaalaa isha shucaaca ka baxsan jidhka bini'aadamka ah wax bililiqaysanaya in burada. Dawaynta ilayska ee gudaha ama daawaynta irradiates buro meelaynta of walxaha shucaaca ee u dhow si degdeg ah gudaha jidhka bini'aadamka. Waxaa loo isticmaalaa in lagu daaweeyo kansarka kaadiheysta, madaxa iyo qoorta, prostate, siilka.

Nooca daaweynta shucaaca iyo dose go'aamiyo da'da ilmaha iyo nooca burada, ay deegaamaynta hore, laakiin sidoo kale ay goobjoog ka ahaayeen buro haraaga ah iyo heerka uu diiwaan gelinta buro qanjidhada dhow qalitaanka ka dib.

chemotherapy

Noocan ah daaweynta kansarka in uu isticmaalaa daawooyinka si ay u joojiyaan koritaanka unugyada kansarka. daroogada Chemotherapy caawisaa dilo unugyada ama si looga fogaado in ay kala qeybinta. A daroogada chemotherapy systemic ayaa laga qaadayaa hadal ahaan ama isku duro intravenously ama intramuscularly. Yimaada dhiig, daroogada saamayn unugyada kansarka ee jidhka oo dhan. Marka daroogada chemotherapy gobolka waxaa si toos ah lagu mudaa xubnaha iyo godadka jidhka, iyo sidoo kale in dheecaanka lafdhabarka. chemotherapy iskujira waxaa badanaa loo isticmaalaa, taas oo daaweynta ah oo loo isticmaalo in ka badan hal daroogada anti-kansarka. Habka chemotherapy la doorto waxay ku xiran tahay nooca iyo heerka horumarka ee neoplasm ah.

Dawaynta kimikalka waxaa la muujiyey in ilmo kasta oo hadda lagu daweynayo for rhabdomyosarcoma. Waxay kuu ogolaanaysaa inaad si loo yareeyo suurtagalnimada ee ku xoogeystay cudurka. Doorashada daawada, qiyaasta iyo tirada nidaamka ku qeexan rhabdomyosarcoma kooxda halista.

Daawooyin cusub

noocyo cusub oo rhabdomyosarcoma daaweynta, imtixaanka marayo:

• qaadasho badan oo chemotherapy lala fulinta xubin unugyada asliga ah. Habka waxa uu ka dhigayaa suurto gal ah inuu abaabulo bedelka unugyada hematopoietic in waa la wada baabbi'iyey intii lagu daaweynta kansarka. Unugyada dhiigga ee aan weli qaan gaadhin ayaa la saaraa ka hor daaweynta dhuuxa lafaha ama dhiigga bukaan oo sii raagayaan. By dhamaadka chemotherapy raskonserviruyut conserved unugyada asliga ah oo ku soo laabtay bukaanka by galiyey. Sayidka unugyada dhiiga in ay cusboonaysiiyaan.
• Immunotherapy. Marka sort this ee daaweynta si ay ula dagaalamaan kansarka isticmaalaya nidaamka difaaca jirka ee bukaanka. daawooyinka maamula waa in la hagaajiyo ama soo celiyo ee difaaca dabiiciga ah soo wajahay cudurka kansarka. daaweynta Tan waxaa lagu magacaabaa biotherapy of burooyinka.
• therapy Beegsado. Noocan ah therapy waxaa lagu jiheeyo metastasis. therapy Beegsado ku salaysan yahay isticmaalka antibodies gaar ah in loo xidho unugyada kansarka. antibodies waxay la mid yihiin unugyada caadiga ah ee jidhka aadanaha yihiin. Oo saasna waxay u taagan yihiin daroogada farsmada heerka sare ah. Thanks to therapy beegsaday in daaweyn jiray "chemistry" waxaa laga heli karaa si ay u weeraraan unugyada kansarka oo kaliya oo aan wax yeesho unugyada caafimaadka qaba. Marka rhabdomyosarcoma in inhibitors angiogenesis waxaa loo isticmaalaa sida therapy bartilmaameedka. Daawooyinkan waxaa looga hortago formation of xididdada dhiigga ee burooyin. Tani waxay keenaysaa in xaqiiqda ah in starves burada iyo joogsiyada sii kordhaya. inhibitors Angiogenesis iyo antibodies monoclonal - nooc oo ah wakiilada maray tijaabo loo xakameeyo rhabdomyosarcoma SNMna.