"Mesakol": tilmaamaha loo isticmaalo, dhigooda dhabta ah

colitis Ulcerative iyo cudurka Crohn waxaa lagu arkay bukaanka waa arrin naadir ah. Laakiin, inkastoo taasi, waxaa jira daawooyin badan oo loogu talagalay in lagu daweeyo cudurada. Mid ka mid ah iyaga ka mid ah waa "Mesakol". Tilmaamaha loogu isticmaalo, foomka, warcelin, iyo kharashka lacagta lagu hoos lagu soo bandhigay doonaa.

Halabuurka The, foomka sii daayo, baakadaha iyo description

Drug "Mesakol", dib u eegista ah kuwaas oo qof aad u maqlana, tagaa on sale sida kiniinno cas-brown. Waxay yihiin enteric-dahaarka leh oo ay leeyihiin qaab wareeg ah oo lenticular.

walax ugu weyn ee qalab ay laftu mesalazine (5-ASA). Waxaa intaa dheer waxaa ka mid ah daroogada oo ay ku jiraan qaybaha dheeraad ah sida galleyda, calcium dihydrate phosphate, Rusheyn kartaa la safeeyey, cellulose mikrokristallin, xabagta titanium, hypromellose 2208, Colloid silica, K90 povidone, sodium noqde carboxymethyl, methacrylic acetate acid iyo methyl methacrylate ah, xabagta cas bir ah, macrogol 6000 iyo phthalate dibutyl.

Kiniiniga "Mesakol" macmalay ee strips aluminium iyo baakado kartoonada siday u kala horreeyaan.

Farmashiiste

Ma ogtahay in uu yahay maandooriye "Mesakol"? Tilmaamaha loogu isticmaalo ayaa tilmaamaya in this wakiilka anti-bararka, saamayn of taas oo ku kooban in xiidmaha. Tani waxay hanti ah ee medicament ah ay sabab u tahay awooddiisa ah inuu xakameeyo ereygu wuxuu ahaa ee leukotrienes iyo prostaglandins, iyo lipoxygenase nuutrofilkaagu.

Sidoo kale waa in Waxaan la soco in daroogada loo arkaa gaabisaa socdaalka, phagocytosis iyo degranulation of neutrophils, iyo sidoo kale dheecaanka immunoglobulin by limfosaytis.

Waa maxay guryaha kale daawo ah "Mesakol", qiimaha kuwaas oo hoos ayaa lagu muujiyey? Mesalazine ayaa hawl antimicrobial ka mid ah mid cocci iyo coli Escherichia (mindhicirka).

Pharmacokinetics

Waa maxay soo jireenka ah kiniin oo xuduudaheedu ogeed "Mesakol"? Tilmaamaha loogu isticmaalo sheegayaa in ka dib markii mesalazine maamulka la sii daayay ka soo qolof ah oo ku saabsan 115-165 daqiiqo ka dib, iyo 170-230 daqiiqo ka dib markii kiniinno baabi'inayo.

tixgelin film daroogada Maaddaama dahaarka on 60-80% la sii daayo ee xiidmaha waaweyn, iyo 15-30% - in xiidmaha yar. Xaaladdan oo kale walaxda firfircoon gaadho wareegga systemic kaliya ee lacagta ah 10% qiyaasta. fiirsashada Mesalazine ee plasma waa mid aad u yar yahay.

Isgaarsiinta ee qayb firfircoon borotiinka plasma waa 43%. Waxaa loo tixgeliyaa daroogada iyo metabolites ay caanaha naaska.

mesalazine-shiid sameeyaa ee xiidmaha iyo beerka. Tani waxay soo saartaa N-acetylsalisylsyre-5-aminosalicylic acid.

The bar-nolosha ee 60-120 daqiiqo (iyada oo ku xiran qiyaasta). Soo bandhigay kelyaha daawo oo dhex mindhicirka.

Tilmaamayaasha si aad u hesho daawo

Taas oo daawaynaya cudurada of daroogada "Mesakol"? Reviews dhakhaatiir sheegay in qalab this arrin wax ku ool ah u muuqato in cudurka Crohn iyo ulcerös kolit.

Waa in la ogaadaa in medicament u tixgeliyo waxaa loo isticmaalaa ma aha oo kaliya si loogu soo daweeyo ka mid ah cudurada sheegnay laakiin sidoo kale ka hortaga exacerbations.

Sababo in daawooyinka

Qorayaasha "Mesakol" laguma talinayo:

• in boog ulcer ee nidaamka dheefshiidka,
• cudurrada dhiig;
• kaafi kelyaha ee daran;
• diathesis hemorrhagic,
• ee carruurnimada,
• dhantaalan cagaarshowga daran;
• diidmo in waxyaabaha daroogada;
• la'aanta dehydrogenase glucose-6-phosphate.

Iyada oo daryeel weyn daroogada loo isticmaalo fudud si dhexdhexaad ah adkaanta kelyaha, iyo sidoo kale kaafi cagaarshowga dhexdhexaad ah oo khafiif ah.

Kiniiniga "Mesakol": tilmaamaha loo isticmaalo

Lacagaha laga qaaday oo afka hadhuudh ah oo kaliya ka dib.

Inta lagu jiro sii daridda cudurka waxaa maamula qadarkuu of 400-800 mg (i.e., 1-2 kiniin) saddex jeer maalintii. therapy The waxaa lagu fuliyaa for 9-12 toddobaad.

Waayo, ka hortagga exacerbations isticmaalka daroogada by 400 mg saddex jeer maalintii. Oo looxyadu waxay guud ahaan waa qaab, la cabbo biyaha caadiga ah.

Sidee carruurta in la siiyo daroogada ah "Mesakol"? Shamac, microclysters iyo ganaax - foomkan lagu muujiyay daroogada si uu kids.

dhibaato

Nasiib darro, daawo qaadashada loo arkaa arrin inta badan sababa waxyeelo. Kuwaas waxaa ka mid ah kuwan soo socda:

• pericarditis, tachycardia, xanuunada wadnaha tabinta, hypertension, xabad xanuun, hypotension, uurkuna waa, neefta oo ku qabata;
• lalabo, hoos u xumo, matag, korodhsan transaminases beerka, laab, stomatitis, shuban, hepatitis, calool xanuun, ganaca, afka oo qalala,
• oliguria, proteinuria, crystalluria, hematuria, syndrome nephrotic, anuria;
• wareer, madax-xanuun, dhalanteed, tinnitus, hurdo la'aan, polyneuropathy, gariir, gariirka, niyad-jabka,
• eosinophilia, Torombositobiiniya, dhiig yari (haemolytic, aplastic, ama megaloblastic), Agranulocytosis, dhiig yari, hypoprothrombinemia;
• oligospermia, kacsi la'aanta;
• daciifnimo, photosensitivity, mumps, yaraynta soo-saarka ah ee dareeraha ah ka ilmaysiisa, lupus-sida syndrome, alopecia;
• finan maqaarka, dermatitis, pruritus, bronchospasm, erythema.

Calaamadaha badinta

Astaamaha hab xad dhaafka loo arkaa taag xaaladaha sida lallabo, gastralgia, matag, hurdo la'aan iyo daciifnimo. Si aad u baabi'iyo iyaga waxaa la qoray lavage gastric, caloosha jilciya iyo therapy astaamaha.

Waafaqsan yahay waxyaabaha kale ee

Drug "Mesakol" yaraynaysaa saamaynta "spironolactone" "Furosemide", "rifampicin" iyo sulfonamides. Waxa kale oo ay wanaajisaa saamaynta hypoglycemic of taagayo sulfonylurea, sumoobo ee methotrexate iyo ulzerogennosti corticosteroids.

Waa in la sidoo kale lagu xusay in daawada yaraysa nuugista ee cyanocobalamin iyo sidoo kale waxay kordhisaa saamaynta wakiilada uricosuric (ie, dheecaan blockers embriyaha) iyo wanaajisaa saamaynta daawada xinjirowga.

talooyin gaar ah

• Shuban ka dhaca inta lagu jiro daaweynta "Mesakolom" had iyo jeer ma naxa uusan saamaynta dhinaca daawada. xaaladda noocan oo kale ah waxaa laga yaabaa in ay calaamad u ah ee cudurka sababaya.
• Inta lagu guda jiro soo dhaweynta, qalab waa in si joogto ah ay fuliyeen dhiiga iyo kaadida caadiga ah.
• Haddii qiyaasta la seegay, soo socda waa in la qaato waqti kasta oo kale.
• Inta lagu guda jiro daawaynta daawada iyo dheecaanka jeex kaadida bukaanka la midab laga yaabaa in midab huruud ah-orange ah.

Drug "Mesakol": dhigooda iyo kharashka

Bedel daawada ayaa sheegay in uu noqon karaa iyadoo qofka sida "salazopiridazina", "5-ASA", "Tidokol" "Asacol", "Samezil", "salofalk", "Mesalazine", "Salozinal", "pentasil".

Sidee badan yihiin "Mesakol" kiniin? Qiimaha daroogada tani waa 600-680 rubles (50 kiniin).

dib u eegista macaamiisha

Bukaan-tago "Mesakol" diyaarinta waa dib u eegista aad u isku qasan. Qaar ka mid ah iyaga ka mid ah la sheegay in daroogada ku ool ah oo daawaynaya cudurka xiidmaha. Qaar kalena waxay ku doodayaan in kiniinka waa kuwan aan waxtar lahayn. Sidaas darteed, waxaan si ammaan ah gabagabayn kartaa in "Mesakol" leedahay dhibaato kala duwan oo ku saabsan bukaanka kala duwan.

khasaare ugu weyn ee daawo tani waa tiro badan oo ah sababo iyo dhibaato.