Kiniiniga "Lopedium": diiwaanka, dib u eegista

"Lopedium" - peristalsis daroogada diiqadoodo ah. Waa kaabsal gelatin la qolof adag ah, oo rinji midabka cagaaran boor ama madow (ay ku jiraan a budada dhqaalaha anfac) ama kiniinada cadcad.

guryaha pharmacological

Kiniiniga "Lopedium" (tilmaamaha loo isticmaalo siiyey in this article) ka kooban yihiin walax awood xiriir la receptors opiat xiidmaha. Iyada oo la xidhiidha waxa ay dhaxalsiiyeen sii daayo acetylcholine iyo prostaglandin. Sidaas garaaca wadnaha a waa la dhimay la taaban karo waxay kordhisaa peristalsis iyo marinka farqiga ku meel gaar ah oo cunto ah iyada oo marinka dheef shiidka. Sidoo kale darbiyada xiidmaha nuugo dheecaanka ay soo qarsan ee muruqyada endetarms-.

Pharmacokinetics

Inta badan Loperamide, galay jidhka la nuugo ee mindhicirrada ah, si kastaba ha ahaatee, ay sabab u tahay dheef-pass ugu horeysay ee degdegga ah, bioavailable systemic waa keliya rubuc ka mid ah boqolkiiba.

Iyada oo cilmi-baaris waxaa la helay in daroogada waxaa loo qeybiyaa si ixtiraam leh in derbiga xiidmaha, iyo sidaas ugu xidho si dhaweeyayaasha gaadhya lakabka jubbadda muruqa ah. Badanaa Loperamide xidhana borotiinka, gaar ahaan albumin.

Kiniiniga "Lopedium" (diiwaanka iyaga daroogada si nabadgelyo ah u soocay) ku dhowaad si buuxda u nuugo by beerka, halkaas oo ay ku metabolized, conjugated oo raaca in bile ah. Sababo la xiriira saamaynta aad u xoog badan oo ah marinka hore diyaarinta beerka, fiirsashada of daroogada ee dhiigga waxaa si weyn u dhimay, halka inta soo hartay aad u yar yahay. Daawada si buuxda loo raaca iyada oo kow iyo - afar iyo toban saacadood.

Tilmaamayaasha

"Lopedium" (kiniin) diiwaanka ku talinaysaa in ay dhacdo shuban raaga oo ba'an. daroogada Tan waxaa loo qaadan karaa in ay dadka ku lug leh safarka ( "shuban dalxiis"). Xaaladdan oo kale, daaweynta waa in ay laba maalmood. Si kastaba ha ahaatee, in ay dhacdo ogaanshaha dhiig saxarada soo muhiim ma aha in la isticmaalo daawada si loo ogaado sababaha dhakhtar nno.

sababo

Ha isticmaalin kiniinka ay dhacdo in ay jiraan diidmo in hydrochloride Loperamide ama si kasta oo qaybaha kale ee diyaarinta.

The sababo ugu muhiimsan ee dadka bukaanka ah:

- enterocolitis bakteeriyada, taasoo ka timi hawlaha sheyga gaar ah:

- dabadhiig qaba ba'an, Ulasocto shuban dhiig iyo qandho.

Isku daroogada la antibiotics kasta oo u baahan si taxadar leh u daran. U hubso in aad u sheegto dhakhtarkaaga.

Ha isticmaalin kiniinka "Lopedium" (diiwaanka ka digay bukaanka) ee horumarinta calool, dibiro ama xirma xiidmaha. Iska ilaali lacag haddii loo baahdo si looga fogaado Dulmiga peristalsis.

Sida loo qaadanayo kiniinada "Lopedium"

Daawada waxaa loo isticmaali karaa in dadka waaweyn iyo carruurta ka weyn lix sano. Kaabsol (kiniin) in la wada liqo oo leh biyo nadiif ah wax yar.

In dose shuban raaga iyo ba'an ee dadka waaweyn waa inta u dhaxaysa 4 dejinta mg (laba kumbiyuutarada.). Waayo, carruurta Waa ku filan tahay inay isku waslad. Daawada waa in la qaato ka dib saxaro kasta dabacsan. Heerka maalin kasta ugu badan ee carruurta iyo dadka waaweyn waa lix ilaa siddeed kiniin.

Haddii calaamadaha shuban ba'an baaba'aan siddeed iyo afartan saacadood gudahood, daroogada waa in la joojiyay.

bukaanada waayeelka ah uma baahna saftay sixitaanka qiyaasta gaar ah. mid ah dadka ka cabanaya xanuunada kelyaha. "Lopedium" (kiniin) diiwaanka kuma talinayso in carruurta la siiyo 3 sano jir.

Features of codsiga

Guud ahaan, daawaynta shubanka waa nidaamsan. Haddii bukaanka wuxuu leeyahay fursad uu si ay u qeexaan Asalkeeda cudurka, haddii ay taasi waxaa lagama maarmaan ah si ay u fuliyaan daaweyn gaar ah. Waxaa macquul ah in daawada laguu qoray uu dhakhtarka inta lagu jiro codsiga ah ee therapy antibiotic. Mawqifkaa waxaa la soo dhaweynta ka dhigan tahay "Lopedium" (kiniin) tilmaamaha loo isticmaalo ee carruurta ku talinaysaa therapy inay dib u buuxiyaan electrolytes iyo cabitaan. Tani waa in la sameeyaa haddii ay dhacdo in ay jirto dheelitir la'aanta ah ee electrolytes iyo fuuqbaxa.

Bukaan-socodka oo lagu helay in ay Acquired Immunodeficiency Syndrome (AIDS), shuban waa in si degdeg ah loo joojiyo qaadashada "Lopedium" lacala dibiro.

"Lopedium" (kiniin): Waxbarashada loogu isticmaalo xilliga uurka iyo nuujinta

Dhakhaatiirta ha ku talinaynaa qaadashada daroogada ee haweenka uurka leh iyo kuwa nuujinaya. Tan waxa u sabab xaqiiqada ah in tiro yar oo Loperamide u muuqan kara in caanaha naaska. Taasi waa sababta haweenka "ee gobolka" waa in had iyo jeer la tasho dhakhtar intaadan gadan daroogada.

Dhexgalka daroogooyinka kale

Seynisyahanno jira kiisas dhexgalka daawooyin kaas oo ay leeyihiin sifooyinka pharmacological la mid ah. Daawooyinka in ay leeyihiin saamayn dejiye on habka dhexe ee neerfayaasha, ma lagu dari karaa "Lopedium".

Waa xusid mudan Loperamide in - waa substrate ah P-glycoprotein. isticmaalka wadajira 'Lopedium "iyo quinidine iyo ritonavir keeni kartaa in koror weyn oo fiirsashada dhiigga daroogada ah. Qiyaasta lagu kordhin karaa in laba ama saddex jeer. Saameyn la mid ah ayaa lagu arkay markii itraconazole iyo ketaconazole.

Waxaa la ogaaday in daawooyinka isagoo guryaha pharmacological la mid ah kor loogu qaado waxaa laga yaabaa in tallaabada of dhowr jeer Loperamide. Laakiin daroogada in la dedejiyo ee maraya waxyaabaha mareenka caloosha iyo mindhicirka, on lid ku ah, waxay yarayn ah waxtarkeeda.

badinta

Kiniiniga "Lopedium" (edbinta si loogu isticmaalo qeexayaa calaamadaha xad dhaafka ah) oo keeni karta in khasaaraha ka mid ah isuduwidda, madax-xanuun, somnolence, maskax hurudda, iyo haynta kaadida. Haddii aad ka heli calaamadaha la mid ah, oo aad qaadi karto "Naloxone". Marar dhif ah, caloosha laga maydho dabadeed, oo wax cabbay shaqeysiin dhuxusha.

dhibaato

On finan maqaarka la abuuri laga yaabaa in, ay ka mid yihiin Stevenson-Johnson syndrome, multiforme erythema; barar, cuncun iyo finan.

Daawada xun u saameyn karto on habka dareemayaasha jirka. Bukaan-socodka la kulmi karaan hurdo, luminta isuduwidda, miyirka oo luma, hypertension, iyo gariirka.

Laga soo bilaabo nidaamka dheefshiidka, bukaanka arki kartaa qalalan afka, caloosha oo, lalabo, yaaqyaaqsi, matag, ileus. Bukaan badan ayaa lahaa daal.

Iyada oo taxaddar waa in la isticmaalaa wadayaasha daroogada iyo mashiinada isticmaalka, sida daroogada waxay keeni kartaa hurdo.

foomka Release, halabuurka iyo xirxirida

kaabsal kasta (kiniin) waxaa ku jira laba milligram ee hydrochloride Loperamide. Ka sokow daroogada ugu weyn, iyo diyaarinta ka kooban yahay kaabayaal ah, kuwaas oo, Rusheyn kartaa, milmahayn magnesium, galleyda iyo laktosmonohydrat lactose.

kiniinka lagu iibiyo taarikada, Toban meelood. xirmo waxay noqon kartaa hal ilaa shan finan.

Oo looxyadu waxay leeyihiin midab cad iyo qaab wareeg ah, convex hal dhinac.

Daawada waa in lagu kaydiyaa meel gudcur ah, qalalan oo ka mid ah carruurtu ma gaarto. heerkulka waa in aan ka badnayn shan iyo labaatan darajo. nolosha shelf - shan sano laga bilaabo taariikhda soo saaridda. Daawada waxaa laga iibsan karaa farmashiyaha wax aan qoro. Laakiin ha iloobin in is keeni kartaa cawaaqib xun.