"Coldrex": dib u eegista. "Coldrex Hawtrey": tilmaamaha loo isticmaalo

Mid kasta oo inaga mid ah ugu yaraan hal mar in uu naftiisa wajahay qabow ah. Qandho, san cabudh, madax-xanuun iyo mararka qaarkood waxay calaamadaha kale xun si caajiso in aan doonayo in laga takhaluso oo ka mid ah sida ugu dhakhsaha badan ee suurtogalka ah.

Waxaa la sheegay in ay lagama maarmaan tahay in la Jidka badan calaamadaha si aad ugu bogsiisid macaamilo halkii. Si kastaba ha ahaatee, waayo, daaweynta ee virus caadi ahaan qaadataa ugu yaraan toddobaadkii, oo uu calaamadaha cabsida badan oo u baahan in ay hadda ku dhameysan. Maxaa la sameeyaa haddii ay taasi? Iibso antibiotics? Maxaa dhacaya haddii waqtiga si aad u booqato dhakhtar gabi ahaanba ma jirto?

"Coldrex" (dib u eegista ah oo arrin wanaagsan yihiin) - daroogada ah in jidhka ka caawiyaa si ay ula dagaalamaan astaamaha hergebka iyo ifilada, kuwaas oo:

• yaraynta heerkulka jidhka kacsantahay,
• Waxa ay meesha ka madax-xanuun iyo xanuun ku dhaca xubnaha iyo muruqyada,
• baabi'iyo sanka oo xirma;
• saaraysaa xanuunka dhuunta.

"Coldrex", qiimaha oo kala duwan 150 rubles 300 rubles kiniin ee baakidhka budada, waxaa laga heli karaa shiidaa farmashiye kasta oo magaalada ka mid ah Russia. Daawada waxaa la heli karaa warqad dhaqtar la'aan.

Waxa aanu keenaan hurdo iyo meesha calaamadaha dib marka ugu horeeysa.

Manufacturer yara

"Coldrex" (dib u eegista ay ku saabsan waxaan ka fiirsan doonaa ka dib) waa wax soo saarka shirkadda dawooyinka ee dunida caanka ah "GlaxoSmithKline". waxaa dib la aasaasay sannadkii 2001, oo maanta la xisaabay in ku dhowaad 6% ka mid ah suuqa dawooyinka dunida.

xarunta ay ku yaalaan UK, laakiin "GSK" xafiisyada wakiilka in 114 dal oo dunida ah, halkaas oo ay jiraan 24 laboratories iyo 78 warshadood. waxyaabaha GSK waxaa lagu qaybiyey in ka badan 150 dal oo dunida ah.

Sida loo doorto wax soo saarka ee kugu habboon?

Waxaa jira fursado dhowr ah "Coldrex" daroogada. Ay ka kooban ma aha lagama maarmaan, laakiin waa kala duwan. daroogada waxaa laga heli karaa kiniin ama budada xal. Qeybta hoose waxaad ka heli doontaa sharaxaad faahfaahsan ee noocyada kasta.

macnihiisu yahay "Coldrex". kiniiniyada

Qaabkan daroogada la sii daayay oo ah qaab kiniin bilayer kapsulovidnyh hal lakab midabka orange, kii labaadna wuxuu ahaa - white. On hal dhinac oo looxyada ku saaray qorniinkan "Koldreks". Halabuurka The of hal kaniini waa sida soo socota:

• 500 mg ah acetaminophen,
• 30 mg acid ascorbic;
• 25 caffeine mg,
• 20 terpine mg,
• 5 hydrochloride phenylephrine mg.

Sidoo kale in kiniinka, waxaa jira excipients gaar ah:

• 103,5 mg istaarijka hadhuudh,
• 30 mg istaarijka pregelatinized;
• 12,47 Rusheyn kartaa mg,
• 6,24 mg stearic acid ,
• 4 mg ah povidone;
• 0.8 mg ah ee sorbate potassium,
• 0.8 mg ah sodium lauryl sulfate,
• 0.4 mg ah ee E110 dheeha (qorrax huruud).

Iyada oo ku saleysan ka kooban kiniinno ah, waxaa lagu soo gabagabeeyey karaa in tallaabada of hal kaniini waa wax yar taagta daran (paracetamol tirada yar ee ka kooban firfircoon) ka badan daroogada "Koldreks" (budada).

Hoos edbinta on Koldreks looxyadii ' ".

foomka ku habboon sida maamulka afka. Waayo, dadka waaweyn iyo carruurta ka weyn yahay 12 sano waxaa lagu talinayaa in ay qaataan laba loox oo ilaa 4 jeer maalintii. Waxaa intaa dheer, waa in u dhexeeya qiyaasood oo ku saabsan 4 saacadood noqotay. Tirada guud ee kiniiniyada qaaday maalintii aan ka badnayn 8 xabbadood.

Caruurta 6 ilaa 12 sano jirka ah waxaa lagula talinayaa in ay qaataan mid ka mid ah kor u kiniin ilaa 4 jeer maalintii. Tirada guud ee maalintii - wax ka badan 4.

Carruurta ka yar da'da 6 sano oo aan talo dhakhtar in ay qaataan daawo this ma noqon karaan.

Sidoo kale, aan ka badnayn qiyaasta lagu taliyey maalin kasta, oo waxay qaadan "Coldrex" dawooyin kale oo gaar ah (fiiri "Falgallada" koldreks qaybta "daroogo kale"). Muddada daaweynta waa in ay iska ilaaliyaan caffeine, sida ay u horseedi kartaa dhibaatooyin aan loo baahnayn ee daroogada (fiiri "Side Effects" section).

Haddii calaamadaha weli daaweynta ka dib, fadlan la xiriir dhakhtarkaaga.

Diyaarinta "Koldreks (budada) MaksGripp"

"Koldreks MaksGripp" - diyaarinta ah ee budo ah oo loo isticmaalo diyaarinta xal. budo Tani waa fudud yahay huruud ah leh ur liin. Waxay u kala diray biyo kulul iyo foomamka xal xumbo ah turbid hurdi aan, sida urta liin. Waxaa loogu talagalay qofku cuno.

"Koldreks" - bacaha (kasta 5 g) waxay ka kooban yihiin:

• 1000 paracetamol mg,
• 40 mg acid ascorbic;
• 10 mg hydrochloride phenylephrine ;
• 3725 mg ah sucrose,
• 680 mg of qaarna;
• 430 mg sitraydh ah sodium,
• 200 mg istaarijka hadhuudh,
• dhadhan liin 200 mg,
• 79 mg ah cyclamate sodium ,
• 54 mg saccharinate sodium,
• 7 mg E100 colorant (curcumin);
• 2 mg ah Silicon Kolloidol dioxide.

Sida aad arki karto, ee "Coldrex MaksGripp" caffeine ma. Si kastaba ha ahaatee, joogitaanka sucrose waxa ku jira ayaa sheegay in haddii aad qabto sonkorow, dulqaad fructose ama cudurada la midka ah, waa in aad ka fogaadaan la isticmaalayo daroogada this.

Sidaas darteed, waxaan baaro daawada "Coldrex" (budada). Tilmaamaha isticmaalka hab hoos ku qoran.

Si aad u diyaariso xal si ay u milmaan ka kooban hal guntin in wareegyada kala badh biyo kulul. Haddii aad rabto in aad ku darto, ka dibna biyo qabow iyo sonkor ay u dhadhamiyaan.

Daawada waxaa loogu talagalay dadka waaweyn oo keliya.

The dose maalin kasta ugu badnaan ka dhigan tahay - 4 guntin, la Goynta in 4 saacadood inta u dhaxaysa dhaweynta kasta.

Waxaa laguma talinayo in ay sii wadaan daaweyn muddo ka badan 5 maalmood. Haddii inta lagu jiro waqtigan calaamadaha ayaa maray, waa in aad la tashato dhakhtar.

Diyaarinta "Koldreks (budada) hotra"

Oo macnaheedu yahay "Koldreks hotra" ka duwan "MaksGripp" diyaarinta kaliya xaddiga qayb maamulaha firfircoon (paracetamol) dhexdeeda yar yar. Inta kale waa dejinta la mid ah sida budada ah, taasi oo ka kaas oo, xal u ah maamulka afka.

Bixi waxa noocyada kala duwan ee ay leeyihiin daroogada this ka mid ah dadka "Coldrex" liin iyo malab, liin ah dareenka, iyo dalalka qaar ka mid ah, waxaa jira noocyada kale oo badan oo, nasiib daro, ma aad caadi u ah in Russia. Waxaan eegeynaa si dhow "Hawtrey. Lemon "iyo" Hawtrey. Lemon iyo Honey. "

pack kasta oo daroogada "Coldrex Hawtrey. Lemon "wuxuu ka kooban yahay:

• 750 mg ah acetaminophen,
• 10 mg hydrochloride phenylephrine;
• 60 mg acid ascorbic;
• 600 mg of qaarna;
• 40 mg saccharinate sodium,
• 500 mg sitraydh ah sodium,
• 50 mg ah tetraroma liin 100%;
• dhadhan liin 83,33 mg,
• 0.75 dheeh huruud mg quinoline (E104);
• 2904,42 mg ah sucrose.

Waxaan dib u eegid kooban oo ka mid ah "Coldrex Hawtrey" daroogada. macnaheedu waa codsan Guide waa la hoos ku qeexan.

Waxa uu ka kooban guntin waa in la kala diri ee koob kala badh biyo kulul (ma kulul). Waxaad ku dari kartaa sonkorta ay u dhadhamiyaan, ama si uu u khafiifiyo xalka biyo qabow.

Qalabkani waxa uu laguma talinayo caruurta ka yar 6 sano. Caruurta 6 ilaa 12 sano jir ah wuxuu qaadan karaa daawada "Coldrex" aan ka badnayn 3 jeer maalintii hal guntin. Adult - wax ka badan 4 jeer in mid ka mid ah bacda dawada.

Oo macnaheedu yahay "Lemon iyo Honey. Coldrex Hawtrey "tilmaamaha loo isticmaalo kaas oo la mid ah sida in of liin ah, dhab ahaantii, oo ka kooban waxaa ka mid ah ma aha badan oo kala duwan.

Halabuurka The of hal bac (5 g):

• 750 mg ah acetaminophen,
• 10 mg hydrochloride phenylephrine;
• 60 mg acid ascorbic;
• 600 mg of qaarna;
• 10 mg saccharinate sodium,
• 500 mg sitraydh ah sodium,
• 100 antaynka-163 dhadhan liin mg 671;
• 75 mg ah dhadhan malab PFW-050,860;
• 125 mg of dhadhan malab Felton F7624P;
• 50 mg 626 colorant karamell,
• 200 mg istaarijka hadhuudh,
• 50 aspartame mg,
• 2468,50 mg ah sucrose.

Sida aad arki karto, walaxda firfircoon ku sugan yihiin isku mid ah iyo in lacagta la mid ah, si ay u dhaqmaan ee jirka ku jira, noocyada kuwaas oo si isku mid ah. Faraqa kaliya ee qadarka wax dhadhan iyo iidaamo. By habka, in diyaarinta "Coldrex. Lemon iyo Honey "malab this, ama ugu yaraan ay soosaaray, ma. Waxaa jira dhadhan joogo oo kaliya malab.

Diyaarinta "Koldreks (budada) Junior"

Waxaa loogu talagalay in loo isticmaalo by carruurta 6 ilaa 12 sano. Waxaa sidoo kale laga heli karaa sida budada ah midab huruud ah iftiin, oo si xal loogu diyaariyo.

Curiska mid guntin "Coldrex Junior" wax soo saarka:

• 300 mg acetaminophen,
• 5 mg ah hydrochloride phenylephrine;
• 20 mg acid ascorbic;
• 21.5 saccharinate sodium mg,
• 31, 5 mg ah cyclamate sodium,
• 340 mg of qaarna;
• 215 mg sitraydh ah sodium,
• 100 mg istaarijka hadhuudh,
• 1862,5 sucrose mg,
• dhadhan liin 100 mg,
• 3.5 mg ah ee E100 curcumin dheeha;
• 1 mg ah Silicon Kolloidol dioxide.

Sida aad arki karto, qalab kale oo taxanahan ka kooban paracetamol ka badan daawo "Junior Coldrex" (budada). arjiga ku of qalab this, fiiri tilmaamaha hoos ku qoran.

Diri karaa guntin in koobab kala badh (125 ml) biyo kulul. On codsi, qasi jiray biyo qabow, ku dar sonkorta.

Waxaan ku talinaynaa isticmaalaya mid ka mid guntin 4 jeer maalintii. Continue daaweynta wax ka badan 5 maalmood.

Dhexgalka macnaheedu yahay "Coldrex" daawooyin kale

Wixii sahlanaato, oo gooni ah la qoro dhexgalka ee qayb kasta daawooyin kale oo firfircoon.

paracetamol

The qayb weyn ee firfircoon oo awood u leh si kor loogu qaado saamaynta daawada xinjirowga (wakiilada in looga hortago formation of prothrombin beerka - daroogada "Warfarin", "bishydroxycoumarin", "Sinkumar", iwm), taas oo si weyn u kordhiyaa khatarta dhiig. saamayn Tani kaliya dhacdaa iyadoo la isticmaalayo soo noqnoqda.

Iyada oo la isticmaalo isku mar ah inducers of falgalka qayilo microsomal beerka (daawooyin sida "Difenin", "carbamazepine", "Rifampicin", "phenytoin", "Zidovuin", barbiturates, murugada tricyclic) la paracetamol kordhay tallaabo gepatoksicheskogo halis.

Paracetamol ayaa sidoo kale yareyneysa waxtarka daawooyinkaan durayo iyo kordhisaa saamaynta ethanol, suuxin, MAO.

phenylephrine

Waxay keenaysaa in kordhay cadaadiska dhiigga inta aad qaadanaysid a inhibitor MAO. Yaraynaysaa waxtarka daawooyinkaan antihypertensive kordhin kartaa halista ah ee soo koraya hypertension, iyo sidoo kale cudurada of nidaamka wadnaha.

Marka ay maamusho la halothane kordhisaa halista baarutaan ventricular.

-Psychotics anti kala duwan, anti-niyadjabka, taagayo phenothiazine maamulka isku mar la hogaanka daroogada si haynta kaadida, calool fadhiga, afka oo qalala ah.

ascorbic acid

By reaction la sulfonamides ama salicylates awoodaan si ay u yareeyaan acids Digo kelyaha. Marka qaaday daawooyin kaas oo ay leeyihiin dareen xumadoodu, Kordhiyey heerka of Digo.

Daawada waxaa laguma talinayo in ay isku mar qaadato daawooyin kale paratsetamolsoderzhaschimi, iyo sidoo kale analgesics kale non-maandooriyaha, acetylsalicylic acid, sodium metamizole, ibuprofen, barbiturates, rifamptsinom, daroogada antiepileptic, chloramphenicol, caburka, wakiilada cabudhinayo rabitaanka cuntada, iyo daawooyin kale si ay u debciyaan calaamadaha hargabka iyo durayga .

Sidoo kale waxay ka dhigan tahay "Coldrex" yaynaan karaa natiijooyinka baaritaannada shaybaarka qaar ka mid ah oo waa in aad takhtarkaaga u sheegto in aad ku qaataan daaweynta.

Wargelin Muhim ah!

Paracetamol kiis kasta waa in aan la isticmaalo khamriga, maadaama ay tani waxay keenaysaa in sumoobo beerka!

sababo

All noocyo ka mid ah daroogada "Coldrex" (bacaha budada ah ama kiniin ah) The sababo la mid ah. Sidaas daraaddeed, waa in aadan qaadan macnihiisu yahay "Coldrex" haddii:

• aad leedahay diidmo in qayb ka mid ah Halabuurka daroogada;
• ayaa si daciif ah kelyaha ama beerka (muujiyeen xitaa wax yar);
• aad tahay qof la taliya-waxqabad ee qanjirka thyroid (tayroodh ama thyrotoxicosis);
• Aad sonkorow qabto ama aad qabto ah cudurada la iska dhaxlo ee la xidhiidha nuugista oo sonkor ah (wax soo saarka ee ku jira sonkor!);
• aad qabtid cudurka wadnaha (myocardial Wadnaxanuun ba'an, tachyarrhythmia, stenosis aortic);
• aad qaadato mid ka mid ah daawooyinka murugada tricyclic, beta-blockers, MAO, ama sidii hore ka badan 14 maalmood ka hor joojiyay qaadashada;
• aad qabtid dhiig-karka,
• aad qaadato daawooyin kale oo ay ku jirto paracetamol,
• aad leedahay adenoma prostate;
• aadan haysan 12 sano;
• aad leedahay dulqaad fructose, la'aanta sucrose (isomaltase), ama aad leedahay nuugeynin glucose-galactose.

daroogada waxaa lagu qaadan karaa, halka ixtiraamaya koombo oo digniin, haddii aad:

• Hiddo, maqnaanshaha dehydrogenase glucose-6-phosphate,
• hyperbilirubinemia benign,
• pheochromocytoma;
• cudurka vasospastic (Raynaud ee syndrome);
• cudurada ka mid ah nidaamka wadnaha iyo.

Marka nno kor ku xusan waxaad u baahan doontaa inaad la tashato dhakhtarkaaga ka hor inta aysan "Coldrex" daroogada.

Waxaa sidoo kale lagu talinayaa in la tasho dhakhtar haddii aad uur leedahay ama naas-nuujinta.

waxyeellooyin

Wixii sahlanaato, dhibaatooyinka ayaa sidoo kale lagu tilmaamay inay by walxaha firfircoon oo iyaga ka dhigi, iyo qaababka xubnaha.

paracetamol

Aad ayay u yar sababa waxyeellooyin.

• Dareen-celinta xasaasiyadeed keeni kartaa shoog, finan maqaarka, anjioedema, urtikaria, Stevens-Johnson syndrome.
• neefsashada, aad u dhif ah bronchospasm in bukaanka qaba dareen dheeraad ah si ay u acetylsalicylic acid iyo NSAIDs kale.
• Beerka iyo biliary siyaabood: cillad beerka arrin naadir ah.
• Xirrira HAY'ADAHA: keeni kartaa leukopenia, Torombositobiiniya ama Agranulocytosis (aad u yar).

phenylephrine

Badanaa wuxuu leeyahay waxyeelo.

• habdhiska: inta badan ka dib markii qaadashada daroogada ayaa laga yaabaa inuu madax xanuun, hurdo la'aan, madax wareer, xanaaq.
• nidaamka wadnaha iyo, marmar dhif ah loo horumariyo karaa tachycardia. kooxda inta badan soo noqnoqda saamayn waa in kor loo qaado dhiig-karka.
• nidaamka dheefshiidka: Phenylephrine inta badan sababa lalabo iyo matag.
• Dareemeysaa: waxaa suurtagal ah in ay aragto furanto ardayga (mydriasis).
• cadaanyo: urtikaria, finan maqaarka xasaasiyad, dermatitis - waxyeelo Rare of phenylephrine.

ascorbic acid

waxay keeni kartaa finan maqaarka ah ama barrar, cuncun of mareenka caloosha iyo mindhicirka.

Fadlan la soco in qaab kasta oo waxyeelo aad u baahan tahay inaad la tashato dhakhtarkaaga isla markiiba haddii ay dhacdo wax kasta oo aan la daweeyo naftaada.

Haddii aad isku aragto muuqaalka kore ee waxyeellooyin kale aan kor lagu sharaxay, waa in la wargeliyo takhtarka.

badinta

Haddii aad ogtahay waxa aad isticmaashay badan oo daroogada ah ka badan waa loo baahan yahay, laakiin aan lahayn wax calaamado ah qiyaasta xad dhaafka, waxaad weli u baahan tahay inaad caawimaad weydiiso dhakhtarkaaga, maadaama ay jirto halis ah in dhaawac beerka raagay.

Sidaas daraaddeed, calaamadaha kasta badinta walax firfircoon faah faahsan u sharax kooban oo ka mid ah daroogada iyo daaweynta.

paracetamol

Calaamadaha badinta:

• inta lagu jiro 24 saacadood ee ugu horeeya ka muuqan karaa jirka oo caddaado, dareen ah lallabo, matag, hoos u dhici doono rabitaanka cuntada, calool xanuun,
• 12-48 saacadood ka dib soo noqdaan noqnoqon beerka.

Marka aad hesho in ka badan 10 g of paracetamol muujiyey waxqabad transaminases soo kordha "beerka". Marka lagu sumoobo paracetamol horumarinta beerka oo daran, taas oo horseedaysa encephalopathy cagaarshowga ama xataa kooma ama dhimasho.

Daaweynta badinta:

• saacadaha ugu horreeya waa la jecel yahay in ay qaataan kiniinnada dhowr dhuxusha firfircoonaan iyo si degdeg ah raadsataa daryeel caafimaad. Next, aad waa in aan la daaweyn madax banaan.

phenylephrine

calaamadaha xad dhaafka ah oo la mid ah la waxyeelo ay kala yihiin:

• ugu horreeya oo dhan waxaa jira wareer, madax xanuun, hurdo la'aan, kordhay cadaadiska dhiigga, lallabo, matag,
• xaaladaha daran, waxay noqon kartaa mid dhalanteed, gariir, arrhythmia.

Is-daaweeyo xad dhaafka ah ee phenylephrine waa wax aan macquul aheyn.

ascorbic acid

Inta ay in ka badan 3000 oo sabab mg shuban osmotic, rabshooyin ee marinka dheef shiidka - calool xanuun, lalabo, matag. Marka la ogaado mid ah calaamadahan, isla markiiba raadso daaweyn.

Drug "Coldrex": dib u eegista

Bilowga maqaalka ayaa sheegay in dib u eegista ay ku saabsan "Coldrex" waxaa loola jeedaa wanaagsan oo ku filan.

Waa run in ka badan nus ka mid ah dadka qaadanaysid dawadan, si togan hadlay isaga ku saabsan.

Laakiin dhinaca xun wali waa ay jiraan:

• tiro badan oo waxyeelo;
• qiimaha sare;
• paracetamol badan ka kooban.

Tani waxa ay ahayd oo dhan ku xusan maqaalka, laakiin waxaa lagama maarmaan ah in ay mar kale in ay jiraan qaar ka mid ah minuses in diyaarinta wax ku adkaysato.

Faa'iidooyinka sida ay tahay kale oo badan:

• uu u asiibi karo astaamaha hergebka iyo ifilada,
• Waxaa dhadhan wanaagsan;
• waxaad qaadan kartaa caruurta iyo dadka waaweyn labadaba;
• kiniiniyada si weyn loo fududeeyo habka daaweynta (qaar ka mid dhadhan xun xal la mid ah);
• in diyaarinta Waxaa jira dhowr dhadhan;
• Baakadaha haboon.

analogues Qaar ka mid ah "Coldrex" daroogada

Nasiib darro, qiimaha lacagta waa mid qaali ah, sidaas darteed dadka qaarkood ay raadinayaan dhigooda oo tayo sare leh.

Dhab ahaan, waxaa jira qaar ka mid ah qalabka aan ku kala duwan yihiin oo ay Halabuurka iyo aad bay uga jaban tahay daroogada "Coldrex". Analogs oo ka mid ah waa sida soo socota:

• "Theraflu" budo. Waxaa ku saabsan qaybta qiimaha isku daroogada "Coldrex" waa. Halabuurka ee isku.
• Drug "Maxicold". Absolutely Halabuurka la mid ah, oo ay kharashka kama badna 150 rubles, taas oo ka hooseeya qiimaha dawooyinka "Koldreks" ama "TeraFlu".
• Oo macnaheedu yahay "Flyukodeks-C." Halabuurka isku mid, qiimaha la aqbali karo - oo ku saabsan 80 rubles.
• "Prostudoks" budo. qalab kale oo la mid ah in Halabuurka, laakiin qiimo aad uga hooseeya. Daawada waxaa laga iibsan karaa 70 rubles.
• macnihiisu yahay "Inflyunorm". Its qiimaha ku saabsan yahay $ 100, iyo qaab-dhismeedka isku mid ah in "Coldrex" daroogada.

Wixii macluumaad dheeraad ah, la xiriir farmashiyada magaalada aad. Waxaa loo baahan yahay ma aha si ay u iibsadaan daawada "Coldrex". Analogues waxa ay sidoo kale waa mid aad wax ku ool ah.

Waxaa laga yaabaa in, farmashiistaha farmashiyaha ayaa kuu sheegi doona wax soo saarka kasta oo, kaas oo kor ku xusan.

Sidaas daraaddeed, in this article waxaan eegay daroogada "Coldrex": dib u eegista, halabuurka, habka isticmaalka, waxyeelo, badinta iyo muuqaalada kale ee ay.

Xusuusnow in daroogo kasta ma aha sida ammaan ah sida waxa ay u muuqataa. Iyo daroogada "Coldrex" (budo iyo kiniiniyada), tilmaamaha loo isticmaalo oo aan loo arkaa maanta, sidoo kale ma nabdoon.