Acetone Halitosis

Qaar ka mid ah isbedel jidhka dibadda sida finan, midab maqaarka, gaar ahaan xaako, afka ur, waxaa muddo dheer loo by takhaatiirta in cudurka of cuduro gaar ah. Acetone ka xun ur kaadida, maqaarka ama afka laga yaabaa in calaamadaha cudur oo kala duwan: diabetes kowaad ama labaad nooca, atsetonemichesky syndrome, dhibaatooyinka wadnaha, cudurada faafa iyo calaamadaha kale ee caafimaad darrada. Urka ilmaha neefta acetone ama qof weyn oo lagu sharaxay by ah ee farsamo adag, sida caadiga ah waxa aanu ku xiran tahay da'da. Tan waxa u sabab korodhka meydadka ketonka dhiigga aadanaha: acetoacetate (H3C-CO-CH2-COOH ) iyo β-hydroxybutyrate (H3C-CHOH-CH2-COOH ).

gobolka dheefshiidka oo waxaa keena sare ee jirkooda ketonka sameeyay intii lagu kala daatay ee acids dufanka leh, loo yaqaan ketoacidosis. Waa xaalad cudur ah hababka dheefshiidka waxaa sabab u ah xaqiiqada ah in jirka uu awoodi waayo in ku filan nidaaminaya soo saarka ee ketones, acids Keto ururto oo sabab u ah isbedel iyo pH dhiigga. In xaaladaha khatarta ah ketoacidosis noqon karaan kuwo raga. gobolka Tani dheefshiidka waa ugu badan ee cudurka macaanka nooca ugu horeysay.

isticmaalka muddo dheer ee khamriga dhacdaa ketoacidosis khamriga, halka sidoo kale u muuqda acetone ur neefta ay sabab u content ee acetone in neefta, taasoo byproduct ah ee bololka u isxilqaamay ee acetoacetic acid. Waxaa inta badan lagu tilmaamay Faydi polish ah caraf dareere ah.

At sare ee gulukooska ee dhiigga (hyperglycemia), ay keento la'aanta insulin (diabetes ugu horeeyay ee nooca) ama unugyada kari waayeen in ay si fiican u jawaabaan insulin (nooca labaad ee sonkorowga) keenaysaa in koror dheeraad ah ee aysidhka ee dhiigga. In dadka caafimaadka qaba, sida caadiga ah ma dhici sababtoo ah ganaca soo saarta insulin ku filan, ama unugyada si fiican u jawaabaan filan ah ee hoormoonka a by beeryarada. Sidaas darteed, glucose galo unugyada (ma ay joogin gaajaysan), ay fiirsashada in dhiig aan la sii kordhaya, mana jirto wax jawaab u korodhka fiirsashada of meydadka ketonka dhiigga. Sidaa darteed aadanuhu caafimaad (ka cabanaya ma diabetes) neefta acetone maqan ur.

In bukaanka sonkorowga, ketoacidosis waxaa ku weheliyay hyperglycemia (serum sonkor dhiig oo sareeya) iyo fuuqbax (dehydration). Midddani of glucose keeni karta in wax soo saarka la xakamayn maydadka ketonka (iyada oo loo marayo dheef dufan acid), xaalad taas oo ay jirto ur neefta acetone in ilmo ama qof weyn. Natiijadu waxay tahay dollar ah kelyaha, glucose kaadida muuqataa (ifafaale u yeedhay glucosuria a), taas oo u shaqeeyo caafimaad oo waxaa resorbed by kelyaha dib u dhex galaan wareegga dhiigga. Contact la glucose kaadida sababta oo ah fiirsashada sare ee dhiigga ku caawisaa in ay khasaare dheecaanka. ketoacidosis Diabetic waa dadka kara nafta halis qaba sonkorowga. Tani waxay badanaa ku dhacda bukaanada qaba cudurka macaanka nooca, laakiin waxa laga yaabaa, in xaaladaha qaarkood, ku dhacaan dadka qaba sonkorowga Nooca II.

In khamriga ketoacidosis khamriga sababa fuuq-bax iyo ka xanibeen talaabada ugu horeysa ee gluconeogenesis - dariiqa dheefshiidka taasoo keentay in jiilka of glucose ka muhashada carbon non-carbohydrate sida lactate, glycerol iyo kuwa kale. Tani waa mid ka mid ah laba hababka ugu weyn ee ay dadka iyo xayawaanka kale uu jidhku u isticmaalo si ay u ilaaliyaan heerka sonkorta dhiigga, taas oo ka caawisaa si looga fogaado in aynaa aad hoos (xaalad loo yaqaannaa hypoglycemia). Siyaabo kale oo dayactirka heerka sonkorta dhiigga waa glycogenolysis - warshadaynta glycogen (reserve carbohydrate). Haddii jidhka oo uusan haysan tiro ku filan oo glucose unugyada xoogga, abuuray dhibaatada tamarta, iyadoo ay sabab u jawaabta maydadka-shiid dufan acid iyo ketonka sameeyay muuqataa ur neefta acetone.

aysiidh jilicsan ku keeni karta soonka sii dheerayn ama cuntada ketogenic (cuntada ka mid ah cuntooyinka ay ku jiraan boqolkiiba sare oo protein iyo baruurtii, carbohydrates yar yahay) taas oo inta badan daawo loo isticmaalo in lagu daaweeyo qalalka dumis ah ee carruurta, cudurrada wadnaha, chronic daal syndrome iyo gobolada kale. cuntada Low-carbohydrate qoray xakamaynta iyo daaweynta cayilka miisaan, sidoo kale yareen ee carbohydrates. Marka marxaladdan hore ee cuntada noocan oo kale ah ka maqan glycogen, oo ku saabsan maalinta a. Markaas, jidhka isticmaalaa for ilo tamareed oo kale (dufanka iyo borotiinka), taas oo loo sameeyay inta lagu jiro suuska ee jirkooda ketonka, oo u muuqda acetone ur neefta.