Waa maxay "Lyrics" kiniin? Isticmaalka qiimaha

Daawo "lyrics" (kiniin), qiimaha oo laga 700 si 4000 rubles, -. Daroogada ku filan si fiican u yaqaan. walax firfircoon - pregabalin - analog ah gamma-aminobutyric acid (Gebacna) (Gebacna). Later maqaalka waxaa lagu siin doonaa annotation in daawooyinka. Ina keena aynu u ogaato waxa kiniinka "Lyrics" isticmaalaya bukaanka.

hab of action

Pregabalin muujinayaa ay oggolyahay ee daaweynta ee neuropathy diabetic iyo neuralgia postherpetic, taas oo kiniinka "lyrics" qoro heerka ilaa 13 toddobaad ee la heerka ah qaato maalin 2 jeer ilaa 8 toddobaad, 3 jeer maalintii. Against asalka ah ee horumarinta hab tilmaamay dhibaatooyinka la mid ah. La xiriira fibromyalgi si cad u yahay hoos u muuqda in calaamado xanuun dhibic halka qaadashada qaadasho daroogo of 300-600 mg maalintii. qiyaasta Daily of 450 mg oo 600 mg la barbar dhigi karaa si loo wanaajiyo, laakiin ugu dambaysta la yar si fiican loo dulqaatay. daroogada waxay yareysaa darnaanta ee suuxdintu, oo kiniin "lyrics" talinaynaa dabcan ka mid ah 12 toddobaad, 2 ama 3 jeer maalintii. Inta lagu guda jiro soo dhaweynta dhacdaa hannaankii la mid ah waxyeelo iyo waxtarka daawada at dose this. inta jeer ee qalal bilaabo inuu hore u yaraado in toddobaadyada ugu horeeya ee daaweynta. Symptomatology ah ciladda wallaaca guud muujinaysaa janjeera in ay yaraadaan in toddobadii maalmood ee ugu horreeya ee daaweynta. sideed todobaad 52% bukaannada daawada qaata pregabalin iyo 38% ee bukaanlayda qaadato jaallaha ah Ka dib, waxay muujiyeen hoos u dhac boqolkiiba 50 ah calaamadaha qiyaasta Hamilton ah (Ham-A).

Pharmacokinetics

The medicament "lyrics" (kiniin) - User Oo Xaqiijiyay In this - in ka qaadasho maalin walba lagu taliyey kooxda pharmacokinetic linearity gartaa, hooseeyo (<20%) tirayn interindividual. codsiga soo noqnoqda oo ka mid ah pharmacokinetics daroogada la sii saadaalin karin ku saleysan unit ka mid ah xogta qiyaasta. Sidaa darteed si joogto ah loola socdo fiirsashada of qayb firfircoon muhiim ma aha. beegyada uu Pharmacokinetic daroogada "Lyrics" in iskaa wax caafimaad leh, bukaanka qaba qallalka hela therapy antiepileptic, iyo sidoo kale qaata daroogada xakamaynta syndromes xanuun la mid yihiin.

Nuugista iyo tirtiridda

Ka dib markii qaadashada on an pregabalin calool madhan waxaa la nuugo si dhakhso ah. Mid ka mid ah saacad ka dib, plasma ku Cmax gaari sida markaad codsanayso markii ugu horeysay, iyo soo noqnoqda. Ku saabsan asalka ah bioavailability afka pregabalin waa at ≥90% oo ka madax bannaan yahay dose. Kortay waxaa lagu gaarayaa marka la qaadanayo soo noqnoqda in mudo ah 24-48 saacadood. Haddii daroogada waxaa laga codsadaa cuntada ka dib, Cmax ah waa la dhimi karaa by 25-30% iyo in la kordhiyo waqtiga guusha ay 2.5 saacadood. Si kastaba ha ahaatee, ma saamayn caafimaad oo muhiim ah oo ku saabsan nuugista ee daroogada ma lahayn cunto. Asal ahaan daroogada saxarrada kelyaha beddelin. T1 / 2 celcelis ahaan 6.3 saacadood.

Pharmacokinetics in xaalado gaar ah

Haddii aad waxyeelleeyey function kelyaha, waxaa lagama maarmaan ah inay tixgeliyaan peculiarity ee ansixin pregabalin, waa si toos ah saamiyeed si ay u ansixin kariyaatiniin. Asal ahaan daroogada saxarrada kelyaha, sidaas darteed waxaa lagama maarmaan ah in kiiska ka mid ah xad gudub ku ah hawlaha ay si loo yareeyo qiyaasta. ka kelyaha reebo, medicament la ool ah ka plasma ah by kelyaha saari karo (fadhiga kelyaha 4-saac siinayaa 50% hoos u dhac ku fiirsashada daroogada ee plasma) iyo qiyaasta daawada ballan ka dibna more suurad wacan. Daraasad gaar ah oo ka mid ah pharmacokinetics ee wakiilada "Lyrics" bukaanka qaba beerka oo yaraada aan la sameeyay.

Pregabalin metabolized dhowaad ma qaawan, waxaa la soo wada bandhigi kaadida ku jirta qaab ciyaareed iska beddelin, si kastaba ha ahaatee beerka si daciif ah aanu si weyn u saameyn kuma fiirsashada of daroogada ee plasma. Marka daroogada waxaa la siiyaa bukaanka ka weyn 65 sano jir, waa in aad ku haay maanka in la da'da Pregabalin ansixin u egtahay inuu hoos u. Haddii qofka waayeelka ah ee hoos function kelyaha, waa hoos loo baahan yahay in daawada dose.

qiyaasta

Inta ay maalin kasta ee diyaarinta lagu qeexay 150-600 mg ah maalintii. Admission waa la fuliyay laba jeer ama saddex jeer, iyadoo aan loo eegin hadhuudhka ah. medicament "lyrics" (kiniin) diiwaanka waxay ku talinaysaa qaadashada leh xanuun neuropathic at 150 mg maalintii. Haddii saamaynta gaareen iyo tolerability wanaagsan dose maalin kasta hal todobaad lagu kordhin karaa ilaa 300 mg (xil "lyrics 300" kiniin). Haddii loo baahdo, qiyaasta ugu badan ee 600 mg maalin kasta waxaa laga yaabaa in ay maamusho hal usbuuc ka dib. Sidoo kale xisaabiyaa qiyaasta at daaweynta qalalka. Sidii lagu kor ku xusan, waxaa lagu talinayaa in daroogada lagu daaweyn jiray fibromyalgi, oo kiniin "lyrics" waxaa maamula in qiyaas ah 75 mg maalintii laba siyaalood. On kordhaya qiyaasta 300 mg saamayn saamaynta gaareen iyo tolerability. Haddii aanu jirin saamayn wanaagsan, sii kordhaysa ee qiyaasta 450 mg, iyo haddii loo baahdo - hal toddobaad 600 mg. Ula dhaqan ciladda wallaaca guud bilowdo dose oo ah 150 mg. Sidoo kale todobaadkii, logu saamaynta gaareen iyo tolerability, dose maalin walba kor u kacay 450 mg, iyo 7 maalmood ka dib - ilaa 600 mg (haddii loo baahdo).

ka saarida daroogada

Haddii loo baahdo, joojiyo daaweynta waxaa lagu talinayaa in loo sameeyo ugu yaraan muddo wiig ah hoos u si tartiib ah in dose. Bukaan-socodka kuwaas oo si daciif ah shaqada kelyaha, fuliyay xulashada gaarka ah ee qaadasho. Haddii ay dhacdo in waxyeello ka soo gaartey in bukaanlayda qaadato macnihiisu yahay "Lyrics" pill-dhigma doorteen khabiir. Waxaa ka mid ah habka ugu badan ee caadiga ah iyo saamayn la mid ah la soo sheegnay waxaa laga yaabaa in dawooyinka "Mydocalm" "Apizartron" "Sedavit" "Ambene".

maragga

Daawada waxaa lagu talinayaa in tirtiridda xanuun neuropathic, sida therapy adjunctive waayo, suuxdin qayb ka mid ah qalalka, in waxaa weheliya ama aan ku weheliyay guud sare. Means tilmaamay for ciladda wallaaca guud dabiiciga ah, iyo sidoo kale fibromyalgi.

sababo

Ma jiraan wax xog ah oo ku saabsan isticmaalka daroogada ee carruurta iyo dhallinyarada ilaa 17 sano loo dhan yahay. In xidhiidh la leh daawada waxaa loo qoondeeyey oo keliya in ay dadka waaweyn. Sababo ka mid ah cudurada la iska dhaxlo, sida dulqaad galactose, deficiency lactase, iyo sidoo kale nuugeynin glucose / galactose. Qalab aan lagu tilmaamay for diidmo. Si ay u ilaaliyaan isticmaalka taxadir leh daroogada ee bukaanka qaba kelyaha iyo wadnaha oo shaqadiisa gaba.

waxyeellooyin

Sida ay waayo-aragnimo ee codsiga caafimaad ee medicament ah, in hurdo calaamadeysan iyo wareer sida cawaaqib aan loo baahnayn. ifafaale Kuwani u muuqdaan in ay ka dhacaan degree dhexdhexaad ah ama sahlan. Ka mid ah waxyeelo kale oo ay keentay in joojiyo daaweynta daroogada, waa in la ogaadaa asthenia, wareer, aragga indhaha oo isku darsamay, incoordination, ataxia, barar durugsan. Sidoo kale ka mid ah saameynta xun xusay madax xanuun, miyirka oo luma, qalal, barar carrabka, shuban, lallabo, keratitis ah. Marar dhif ah waxay leeyihiin maqaarka cuncun leh iyo falcelin angioneurotic. Waxaa jira haynta kaadida, barar sambabada iyo gynecomastia. Ka mid ah waxyeelo kale waxaa la odhan jiray daal.