Product "Levodopa": tilmaamaha loo isticmaalo, sharaxaad, halabuurka, analogs iyo dib u eegis

Waa maxay daawada "Levodopa"? Tilmaamaha loogu isticmaalo, qiimaha, dib u eegista ku saabsan daroogada la yar oo dheeraad ah looga hadli doonaa. Waxa kale oo aad baran doontaa waxa qoray dawadan, haddii uu wax dhibaato iyo sababo, taas oo ay u sameeyaan waa la heli karaa for sale, kaas oo la mid ah in ay ka kooban, iyo wixii la mid ah.

The Halabuurka, qaabka, description

Taas oo ka kooban ku jira daroogada a "Levodopa"? Tilmaamaha loogu isticmaalo muujinaysaa in qayb firfircoon ee daroogada waa levodopa. In la iibiyo waa in qaab kiniin qasabad wareeg midab cad, baakadeeyey sanduuqyada gacanta dusha iyo kartoonada, siday u kala horreeyaan.

Mabda'a hawlgalka ee medicament a

daroogada "Levodopa" Sidee u shaqeeyaan? Tilmaamaha loogu isticmaalo, dib u eegista ayaa soo wariyay in this isku darka wakiilka antiparkinsonian. Waxay ujeeddadiisu tahay in la baabi'iyo ku rigidity, hypokinesia, gariirka, Dhareer iyo dysphagia.

In jidhka, ku simaha qayb daawada waa diinta dopamine (habdhiska dhimirka), oou ilaa yaraanta ee element ah.

Dopamine dhacda in unugyada durugsan, waxay muujinaysaa ma saamaynta anti-Parkinson of levodopa. Tan waxa u sabab xaqiiqada ah in aysan gelin habka dhexe ee neerfayaasha iyo waa sababta ugu weyn ee dhibaato ah ee daroogada.

Si loo yareeyo qiyaasta oo ah walaxda firfircoon ee jidhka bini'aadamka waxaa loo xilsaaray medicament isku dhafan oo inhibitors durugsan dopa-decarboxylase. Farsamada Tani waxay ka caawisaa si loo yareeyo saamaynta dhinaca ka qaadashada kaniiniyada.

Pharmacokinetics

daawo intee le'eg ayaa nuugo "Levodopa"? Tilmaamaha on dalalka codsiga ka dib helitaanka daawada galay jidhka waxaa arrin si degdeg ah nuugo ka soo xiidmaha.

Nuugista oo ah walaxda firfircoon ku saabsan tahay 20-30%. In saamayn this daweynta ayaa lagu arkay kadib markii 3 h.

qaadashada Cuntada (oo ay ku jiraan cuntooyinka qaarkood) si toos ah saamayn ku nuugista of daroogada.

Daawada waxaa metabolized, oon la xirrira dhowr metabolites. Digo oo ah walaxda firfircoon qaadataa meel marayo kelyaha, iyo iyada oo loo marayo xiidmaha.

Tilmaamayaasha

Under waxa xaaladaha bukaanada qoray daawada "Levodopa"? Tilmaamaha loogu isticmaalo sida ay calaamado muujinaya soo socda:

• syndrome postencephalitic dhacda in cudurada cerebrovascular ama sarkhaan sun ah;
• Parkinson ee syndrome, weliba, taas oo sabab u ahaa isticmaalka daawooyinka ee waallida dajiya,
• cudurka Parkinson.

sababo

Haddii ay jiraan sababo in "L-dopa" daroogada? Tilmaamaha loogu isticmaalo ayaa sheegay in daawo kanna waa xaaraan in ay qaataan in arrimaha soo socda:

• diidmo in qaybaha ah;
• weheliso MAO;
• inta aad uurka leedahay iyo inta lagu jiro naas-nuujinta ilmaha;
• bukaanka ka yar 18 sano.

Iyada oo daryeel weyn daroogada la magacaabay karaa:

• emphysema;
• joogitaanka of cudurada sanbabada, cudurrada wadnaha, beerka iyo habka hormoonada jidhka iyo receptacles;
• neefta bronki,
• daliilka psychosis;
• melanoma (oo ay ku jiraan taariikhda);
• gulukooma xagal-xidho,
• qallal soo noqnoqda (qalal);
• glaucoma-xagal furan, taas oo dhacda qaab raaga,
• kelyaha iyo beerka,
• Wadnaxanuun myocardial (taariikhda), iyo sidoo kale noocyo of noocyo kala duwan oo garaaca;
• boog dyspepsia iyo caloosha,
• Habdhiska daliilka dulmi,
• rabshooyin garaaca wadnaha.

Daawada waa "L-dopa": tilmaamaha loo isticmaalo

Description of daroogada ayaa lagu kor ku soo bandhigay. Sida ay waa in ay noqdaan?

Sida laga soo xigtay tilmaamaha, daroogada la qaatay hadal. qiyaasta waxaa si tartiib ah kor u kacay ka ugu yar ugu badnaan (ku xiran tahay qofka bukaanka ah shaqsi).

Bilaabidda daaweynta la dose of a 0.25-1 g Caddadkan waxaa lagu qaybiyey saddex qaybood. qiyaasta waxaa si tartiib ah kor u kacay in 0,125-0,75 g Samee at muddo siman waqti (tus, saddex maalmood), oo diiradda saaraya jawaabta bukaanka qof, ilaa xilligan marka saamayn mug leh oo laga dheehan doonaa ka therapy ah.

Qiyaasta ugu badan ee maalin kasta waa in aan ka badnayn siddeed garaam.

Daawada kiis kasta, ma soo maratay baajiso. Jooji waxaa si tartiib tartiib ah qaadato.

dhibaato

Ma dhibaatooyinka soo raaca daawada "Levodopa"? Tilmaamaha Isticmaalka dhigayaa in ee macnaha guud ee ay soo dhaweynta ee qofka la kulmi karaan qaar ka mid ah dhibaato saamayn ku yeelan hawlgalka oo dhan nidaamka jidhka:

• nidaamka Wadnaha: wadno, arrhythmia, qas cadaadis, reactions orthostatic, syncope, iyo wixii la mid ah.
• mareenka dheefshiidka: shuban, matag, dyspepsia, anorexia, calool, isbedel xagga dhadhanka, afka oo qalala, dhiigbaxa mareenka caloosha iyo mindhicirka.

Sidoo kale waa in la ogaadaa in aan laga saaray reactions dhinaca saameynaya howlgalka of hematopoiesis, kaadida, neefsashada, iyo hababka dareemayaasha jirka. Inta badan ee bukaanlayda qaadato daawada this dareen diidmo oo xasaasiyadeed dhacaan, isbeddel in xuduudaheedu shaybaarka iyo Waxyeellooyin on maqaarka.

Kiisaska of badinta (astaamaha, daaweynta)

In codsanaya qaadasho sare tusay xoojisid weyn oo waxyeelo. Xaaladaha noocan oo kale ah u baahan tahay daaweyn qaab lavage, la socodka xaaladda guud ee bukaan-socodka iyo hawlgalka wadnaha. Haddii loo baahdo, fuliyaan therapy antiarrhythmic.

isdhexgalka daroogada

soo dhaweynta oo wadajira iyo tixgelinta diyaarinta "ditilina" beta-agonister, iyo wakiilada in waxaa loogu talagalay suuxdinta neefsado, waxay kordhisaa suurtagalnimada baarutaan waxyaalaha qalbiga ku jira.

Bioavailability "Levodopa" yareyn kartaa kiniinada farxadda tricyclic.

Isku daroogada la "thioxanthenes," "Diazepam" waallida dajiya "phenytoin" m-holinoblokatorami "clonidine", "Difenilbutilpiperidinom" "Papaverine", "Clozapine", "phenothiazine" "pyridoxine" iyo "reserpine" marar badan waxa ay yaraynaysaa ay saamayn antiparkinsonian.

daawooyinka Lithium kordhin itimaalka ee dhacdo of dyskinesias iyo dhalanteed, iyo "methyldopa" medicament kordhiyaa reactions dhinaca.

isku dhafan ee MAO iyo "Levodopa" keenaysaa in wareegga oo yaraada. Marka tan la eego, bareeg u dhexeeya qiyaasood oo ah daawooyinka, kuwaas oo waa in ay ahaadaan ugu yaraan 14 maalmood.

hoos lagu calaamadeeyay in cadaadis lagu arkay iyadoo isku darka daawada iyo tixgeliyaa "tubocurarine".

Drug "metoclopramide" kordhaya bioavailability "Levodopa" dardar-udhigto. Tani waxay si xun u saameyn karaa cudurka.

talooyin gaar ah in loo isticmaalo ee daroogada

Waxa aad u baahan tahay inaad ogaato ka hor qaadashada kiniiniga "Levodopa"? Tilmaamaha loogu isticmaalo (qiimaha hoose) ka digay ku saabsan khatarta caafimaadka by joojiyo kadis ah medicament ah.

Mararka ay dhacdo in aysan macquul aheyn in ay ka fogaadaan hoos u qiyaasta ama bixitaanka of daawo u baahan tahay la socodka joogtada ah ee xaaladda bukaanka.

Ka hor inta daroogada laguma talinayo inay u baabba'do cuntooyinka hodanka ku ah protein, tan iyo markii ay yaraynaysaa absorbability ah oo ah walaxda firfircoon.

therapy wuxuu u baahan yahay la socodka joogtada ah ee nidaamka, xubnaha, iyo xuduudaheedu kala duwan dhiigga.

Price iyo analogues

The analogues dhow "L-dopa" diyaarinta ka dhigan yahay sida a "benserazide levodopa" iyo "Levodopa Carbidopa". Tilmaamaha loogu isticmaalo ayaa sheegay in daawooyinkan waxay leeyihiin tilmaamo mid ah, waxyeelo, hababka garoomada iyo sababo. farqiga kaliya ee u dhaxeeya lacagta waa ay ka kooban.

Walxaha firfircooni noocan oo kale ah sida carbidopa iyo benserazide yareeyo wax soo saarka ee dopamine in unugyada durugsan, markaa si ay kordhaan xaddiga levodopa galaya yimaada habdhiska dhimirka.

Sidaas darteed, waxaa si ammaan ah in la xuso karo in daawada "Levodopa Carbidopa" iyo "benserazide levodopa" (tilmaamaha loo isticmaalo oo ka mid ah hab ayaa sidoo kale gundhig ee baakada) tiraa inhibitors dhaweynta dheeraad ah durugsan dopa-decarboxylase.

Sida ee facooda kale, ka dibna dambe waxaa ka mid ah daawooyin sida "Isik Meath", "Tremonorm", "Dopar 275", "Tidomet", "Duellin ',' Sinemet ',' Zimoks", "Sindopa", "Isik" "Lac". Waa in ay magacaabi dhakhtar oo kaliya.

Qiimaha "Levodopa" daroogada waa mid qaali ah. In farmasiyada, waxaad ka iibsan kartaa dawadan 1500-1850 rubles gudahood.

Reviews daawo

Daaweynta cudurka kasta Waa in la fuliyo oo keliya ujeeddo ah dhakhtar khibrad leh. Oo Parkinson ee waa laga reebo lahayn.

Bukaanka qaaday "Levodopa" daroogada ee ikhtiyaarka kaliya, oo aan lahayn saamayn togan ku-daweyn. Sidaas daraaddeed marar badan dib u eegista this medicament waa negative. Users ayaa soo wariyay in xataa iyadoo la isticmaalayo dheer ee daawooyinka horumar la taaban karo ayaa sidoo kale lagu arkay.

Haddii daawada loo qaato ka yar tixgeliyo nidaamka, kaas oo waxaa la sameeyey by xirfadle khibrad leh waxaa socda koorsada cudurka, habka daaweynta had iyo jeer waa guul. Tan waxa u sabab xaqiiqada ah in daroogada firfircoon waa in la qaataa in qiyaasta adag, taas oo ku xiran qofka bukaanka ah, astaamaha cudurka iyo arrimo kale.

Bukaan-socodka waxaa si adag waafaqsan mudada daaweynta, ayaa soo wariyay in daroogada "Levodopa" waa mid aad wax ku ool ah ka sameeyay cirib dhibaatooyin caafimaad.

Dhab ahaantii, dad badan oo ka caban ku saabsan qiimaha sare ee dawooyinka. Si kastaba ha ahaatee, khubarada ku andacoodaan in qiimaha daroogada tani waa si buuxda cudur daar.