Neuroblastoma carruurta, 4-yada. Sababaha, calaamadaha, calaamadaha, saadaasha. daaweynta neuroblastoma ilmaha

Neuroblastoma - kansarka a of habdhiska u dabacsanaadaan. Xaaladaha intooda badan, cudurkan la ogaado in carruurta yar yar. Waqtigii ay ogaanshaha kordhiso fursada complete soo kabashada ah. Laga soo bilaabo qalabka of this article waxaad ku baran doontaa sababaha aasaasiga ah ee cudurka, calaamadaha, waxaa ku weheliyay, halkaas oo loo baahan yahay daaweyn.

nooca la yaabka leh ee neuroblastoma in ilmo

Neuroblastoma - ugu badan buro waa malignant qof. Waxa la xisaabay in 15% ka mid ah dhammaan kiisaska la sheegay of burooyinka muddada dhalaanka iyo carruurnimada hore. Khubaradu waxay guud ahaan waxyooday buro ee carruurta jirta ilaa shan sano, laakiin waxaa jira kiisas ah cudurka in dhallinyarada 11 iyo xataa 15 sano. Iyada oo koritaanka iyo horumarka ilmaha ay u badan tahay inuu wajaho cudurkan uga hornimaadno waa la dhimay sanad kasta.

Barar neuroblasts ah, sida ay dhakhaatiirtu, waxaa ka fadilnaa awoodooda la yaab leh. Waxaa si gaar ah mintid ah u nugul metastasis in qayb ka mid ah jidhka. Inta badan xanuunsado tan ay waxqabad ee lafaha iyo nidaamka durey. koritaanka neuroblast Mararka qaarkood dhakhaatiirta go'an Axdigu ay qaybinta formation ku xiga ee burooyin. Waxay marka hore metastasizes, ka dibna uu joojiyo horumarka iyo bilaabo inuu la wiiqo. Carcinogenic of nooc kale oo aan lagu gartaa astaamo sida.

neuroblastoma maskaxda ee carruurta markii ugu horaysay la baarayaa by saynisyahano laga Germany, Rudolfom Virhovym ee 1865. Dhakhtarku wuxuu u yeedhay buro "Gliom." Dhowr sano ee dambe saynisyahan Maraykanka Dzheyms Rayt sahamiyey neoplasm faahfaahin dheeraad ah oo Caddaynay habka ay u sameynta.

Marxaladaha The horumarinta neuroblastoma

Like wax burooyinka kansarka kale, neuroblastoma carruurta maraa dhowr marxaladood ee horumarinta ee caadiga ah, sida lagu qeexay kuu ogolaanayaa inaad inuu ku meeleeyo daaweyn wax ku ool ah:

• Stage 1 waxa lagu gartaa joogitaanka burooyinka resectable kuwaas oo size kama badna 5 cm, iyo maqnaanshaha metastases Guntin lymph.
• 2A Step. Evidence of burooyinka kooban, ugu of taas oo ku xiran yihiin saarista.
• Tallaabada 2B. metastases istiticmaalo si iskeed ah ay dhacaan.
• Step 3. Gartaa muuqaalka burooyinka laba geesood ah.
• Tallaabada 4 (A-B). Neoplasm koraa, waxaa jira metastasis in dhuuxa lafta, beerka iyo dheecaanka qanjidhada.

Sidoo kale waa in aan tixgelin doonna sida heerka ugu dambeeya ee horumarinta neuroblastoma carruurta. Tallaabada 4 ka duwan aan ku waani neoplasias sifooyinka nafleyda nasan, ayaa saadaal wanaagsan, iyo haddii daaweynta waqtigii siinayaa heerka a badbaadista sare.

Sababaha ugu waaweyn ee horumarka burada

Neuroblastoma, iyo sidoo kale noocyo kale oo kansar, waxa uu yeeshay ku saabsan asalka ah Isbedelo hidaha ee u shaqeeyo. Currently, khubaro ma dhihi karo in ay siinaysaa asaasmeen isbedeladan. Waxaa la malaysan in door ka ciyaaray by arrimaha cudurka kansarka ee loo yaqaan, tusaale ahaan, kiimikada iyo shucaaca. The keentay unugyada isbedel bilaabaan inay badanayaan, la xirrira burada. neoplasm malignant lagu gartaa awood u leh inay wadaagaan in ay kala ka benign.

Waxaa isbeddel ah ee ku caasiyoobaan Ilaaha formation of neuroblastoma baxdo muddada horumarinta uurjiifka ama ugu dhakhsaha badan ka dib dhalashada ilmaha. Sidaa darteed, dadka bukaanka ah ugu - grudnichki. asalka ah ee burada bilaabmaa neuroblasts. Tani unugyada dareenka aan weli qaan gaadhin, kaas oo loo sameeyay in ilmaha caloosha ku jiro ay horumarinta intrauterine. In koorsada caadiga ah ee neuroblasts uurka qaadan shaqada macdantaa dareemayaasha ama unugyada ayaa ka mas'uul ah formation of qanjidhada adrenal.

Badankoodu kuwo horay u sameeyay wakhtiga dhalashada ilmaha. Unugyada qaan caadi ahaan ku baaba'aan. Marka geeddi-bahal ee neuroblasts inta lagu guda jiro jeedo this galay buro. caddaynta kaliya ee factor kansarka - cabista hidde. Si kastaba ha ahaatee, halista cudurka dhaxlo kama badna 2%.

Inta badan, dhakhaatiirta ogaado neuroblastoma retroperitoneal, meel uu jecel yahay meesha deegaamaynta - qanjidhada adrenal. Fikrad ahaan, burada bixi kara meel kasta oo jidhka. neuroblastoma Retroperitoneal carruurta ka dhaca 50% ee kiisaska, 30% bukaannada horumariyo qanjira buro ee dareemayaasha gobolka lumbar, soo haray 20% dooran for deegaamaynta ah ee afka ilmo-galeenka iyo thoracic.

Sidee buro?

Marka marxaladdan hore ee geedi socodka bahal calaamadaha gaarka ah aan la arkay. Sidaa darteed, burada waxaa badanaa loo arkaa xanuuno kale oo gaar ah si ay u da 'kooxeedyada this.

Calaamadaha neuroblastoma carruurta dhacaan ku xiran tahay meesha of burooyinka deegaamaynta, meelaha of faafinta xadka- iyo heerka walxaha vasoactive. Sida caadiga ah, Guntin ku buro aasaasiga ah waa in meel bannaan oo retroperitoneal, dheeraad ah si hufan ee qanjidhada adrenal. Marar dhif ah, waxaa ku kooban qoorta ama mediastinum ah.

Sidee neuroblastoma carruurta? Astaamaha cudurka waxa sababa la sii daayo hormoonnada by unugyada kansarka ama burooyin cadaadis joogto ah oo ku saabsan mid ka mid ah ama jidhka oo kale. Mararka qaarkood kobaca saamayn ku shaqaynaya ee mindhicirrada iyo kaadi haysta. Sababo la riixo marinnada dhiigga ee bukaanka waxay dhacdaa xiniinyaha oo hoos u bararka darafkeeda.

dhibco ka guduudan yahay ama buluug on maqaarka ayaa sidoo kale astaamaha neuroblastoma carruurta. Muuqashadii muujinaysaa lug ee geedi socodka bahal unugyada epidermal. Iyada oo wax lays ee burada si toos ah u geliyey dhuuxa lafta of ilmuhu noqdo mid daciif ah, inta badan jiran. Xaaladdan oo kale, xataa dhaawac yar oo keeni kara in dhiig ballaaran.

Ogaanaya calaamadaha neuroblastoma, waalidka waa in la tasho dhakhtar. ogaanshaha kansarka marxalad hore waxay badbaadin kartaa nolosha ilmaha.

neuroblastoma Retroperitoneal

Neoplasm asal neurogenic unugyada dhacda in meel bannaan oo retroperitoneal, lagu gartaa koritaanka saa'idka ah. In muddo gaaban, waxaa guskiisa galay kanaalka laf-dhabarka, la xirrira joogta ah qarada waaweyn oo burada, kaas oo lagu ogaan karaa by taataabasho.

Neuroblastoma qanjirka adrenal in carruurta marka hore ma laha calaamado gaar ah ilaa ay ka gaarayso size cajiib ah oo uu bilaabo inuu lifaaq unugyada ku xeeran. Waa maxay calaamadaha of buro cad?

1. Joogitaanka dhismaha cufan ee saabka caloosha.
2. Barar ama jidhka oo dhan.
3. Raaxo iyo xanuun gobolka lumbar ah.
4. Miisaanka oo yaraada.
5. Korodh heerkulka ah.
6. Isbeddelka ku tilmaamayaasha dhiig markhaati u anemia.
7. Kabuubyo, curyaannimo oo ka mid ah addimada hoose.
8. Murugoodo kartida functional of mareenka caloosha iyo mindhicirka iyo nidaamka kaadida.

deegaamaynta kale ee burooyinka asal neurogenic

Neuroblastoma mediastinum dambe ee carruurta waxaa la socda miisaanka fiiqan khasaare, liqidda oo dhib ah, xanuun dhaqdhaqaaqa neefsiga. Xaaladaha qaarkood, cudurka keenta in isbeddel ku dhacay qaabka of xabadka.

Burooyinka zaglazno bannaan tahay mid aad u dhif ah, laakiin si ka badan oo ku saabsan ogaadaan. Tan waxa u sabab xaqiiqada ah in dhammaan calaamadaha habka a bahal arki karo in ay isha oo qaawan. Neoplasm lagu gartaa muuqaalka kore ee dhibco mugdi ku isha, taasoo u eg burburin caadi ah. calaamad kale waxaa hoos u indhaha neuroblastoma. Waxaana ay ku aaddan bu'da ah sidii dabiiciga ferjiga.

foomamka neuroblastomas

At khubaro joogo kala saaro neuroblastoma afar foomamka, kuwaasoo mid walba uu leeyahay meel gaar ah iyo deegaamaynta sifooyinka kala.

• Medulloblastoma. Neoplasm billaabay qoto dheer cerebellum ah, taas oo ah sababta aan la dhaqaajin karin by qaliin. cudurradana waxa lagu gartaa metastasis deg deg ah. Calaamadaha ugu horreeya ee kansarka muuqan incoordination.
• Retinoblastoma. buro kansar Tani saameeya ileyska ee isha ee bukaanada dhallinyarada ah. la'aanta ah ee daaweynta keenaysaa in total indho iyo maskaxda metastases.
• Neyrofibrosarkoma. buro Tan waxaa ku kooban in saabka caloosha.
• Simpatoblastoma. buro Tani waa malignant, oo waa inuu "guriga" xulayo nidaamka u dabacsanaadaan neerfayaasha iyo qanjidhada adrenal. Neoplasm sameeyay in ilmaha caloosha ku jiro ay horumarinta intrauterine. Sababo la xiriira kororka degdeg ah laf-dhabarta ay saameyn karto in simpatoblastomy size in weeyaan curyaannimo.

Sida loo aqoonsado neuroblastoma?

Marka hore, dhakhtarka kuu qoray cudurka looga shakisan yahay dhiiga iyo kaadida 'Neuroblastoma'. In caruurta, calaamadaha cudurkan la mid ah cudurada kale ee jira, iyo baaritaanka shaybaarka qalabka noolaha meesha sababaha kale ee suurogal. heerka sare ee hormoonnada catecholamine kaadida waxay muujinaysaa jiritaanka kansarka.

Si loo go'aamiyo cabbirka burada, deegaamaynta bukaanada ay dhallinyarada qoray CT, MRI ultrasound iyo. Hab muhiim ah waa biopsy ogaanayo. Inta lagu guda jiro nidaamka this, ku takhasusay dhigaysa unugyada kansarka xayndaabka baaritaan sheybaar xiga, falanqaynta histological ah.

Iyada oo ku saleysan natiijooyinka baaritaanka uu dhakhtarku yeesho xeeladaha daawaynta, talooyin ku saabsan daaweynta iyo jidka nolosha bukaanka.

fursadaha daaweynta

Daaweynta neuroblastoma in ilmo yar waxaa caadi ahaan ku lug leh waaxda kansarka takhasus badan (himioterapevt, qalliin, darsaya). Ka dib markii barashada dabeecadaha burada, dhakhaatiir yihiin horumarinta tabaha ay u baabba '. Waxay ku xiran tahay sida burada ay jawaab u tahay hawlaha ay fuliyeen, iyo saadaasha waqtiga cudurka final.

Guud ahaan, daaweynta neuroblastoma carruurta ka mid ah hababka soo socda:

1. Chemotherapy. Howshaan waxay ku lug leedahay hordhaca ah ee daawooyinka anti-kansarka at a nidaamyada si gaar ah loogu talagalay. Diyaargaraw saamayn dhaawici on unugyada kansarka, ka hortagga ay faafin. iyaga la saameeyey qaybaha kale ee jirka, taas oo keenta in dhibaatooyinka caamka ah (timo ah oo daataan, lalabo, shuban). Saamayntii therapy waxaa kordhay dhowr jeer lala badalida oo dhuux.
2. daaweynta qalliinka ku lug leedahay ka kaxayntu ay of burooyinka. Qaliinka ka hor waxaa laga codsadaa chemotherapy. Waxay kuu ogolaanaysaa inaad hoos si aad u yarayso koritaanka buro iyo sababta dhaca ee metastases. Ogolaashaha afjarto saarista waxay ku xiran tahay meesha iyo size. buro yar oo ku yaal meel u dhow laf-dhabarta, samaynta faragelinta aad u khatar ah.
3. Dawaynta ilayska ee dhaqanka caafimaad oo casri ah waxaa dhif ah loo isticmaalo. Waxaa sii kordheysa waa sannadihii la soo dhaafay bedelay qaliin sidoo kale shucaac ma aha ammaan ah oo xanbaarsan khatar gaar ah si nolosha ilmaha. Dawaynta ilayska waxaa lagu talinayaa in si adag on caddayn ah, marka ay jirto hufnaan yar ee hababka kale ee daaweynta, in ay dhacdo neuroblastoma unresectable carruurta.

cunto gaar ah la cudurka bukaanka yar ma aha tilmaamay. Waalidiin badan ayaa isku dayaysa inay la jiray cayn kasta oo jidadka nolosha ee Chad macaamiloon, qabsato uu cunto. Waxaa caddeeyeen in qaar ka mid ah wax soo saarka ama, more hufan, walxaha ku jira iyaga oo ku, la kordhiyo difaaca jidhka oo ay u muuqata la xakameeyo koritaanka burooyinka. walxaha noocan oo kale ah waxaa ka mid ah zinc, iyo birta, betaine, fitamiinada kala duwan. Waxay hodan ku ah miraha liinta, cagaarka dhalinyarada ah, karootada, bocorka yihiin.

Guusha daaweyn walba ku xiran tahay neuroblastoma sida weyn ee carruurta. Sababaha cudurka iyo marxaladda cudurka sidoo kale waa muhiim. isticmaalka hababka xagjirka ah ee marxaladaha hore ee formation buro siinaysaa rajo buuxda u soo kabsado. Si kastaba ha ahaatee, taasi ma caawin bukaanka yar oo ku saabsan booqashada dhakhtarka oo marayay baaritaanka si looga hortago soo noq-a suurto gal.

Itimaalka kabashada final aan la saaray in talaabada labaad, ay shardi tahay in qalliin lagu guuleystey iyo chemotherapy.

dhibaatooyinka qaarkood kac ku jira marxaladaha dambe ee cudurada sida neuroblastoma. Caruurta 4-yada kansarka ah waxaa inta badan la socda saadaasha niyad jab. Noqoshada waxaa suurtagal ah ka dib saarista burada, ku saabsan asalka ah ee muuqda kabashada. Oo qarniga soo socda oo ah nooca malignant waxaa sida caadiga ah la sameeyay in meel ka mid ah, halkaas oo ay hore u ahayd. Saadaasha for tallaabo this waa 20% badbaado muddo shan sano ah. Xaaladdan oo kale, wax walba waxay ku xiran tahay tababarka ee ku takhasusay, helitaanka qalabka caafimaadka ee loo baahan yahay.

Odoroska

Ka dib markii intensive saadaasha cudurka kansarka therapy for bukaanka ugu badan waa wanaagsan. Caruurta leh habka buro kooban, waxaanay dhakhaatiirtu sheegeen in ay u badan tahay inuu ka soo kabsado sida ugu dhaqsaha badan. Iyadoo la tixgelinayo in this category ka mid ah bukaanka, burada laga yaabaa xitaa iyada oo aan qalliin, laakiin daaweynta caafimaad oo degdeg ah ay dhacdo in this waa waajib. In carruurta waaweyn, isagoo kala bixiyeen burada, fursadaha complete soo kabashada waa aad u hoosaysa. Waxaa intaa dheer, burada soo noqnoqon karaan.

natiijo daaweynta inta badan ciyaara neuroblastoma sare ee carruurta. Saadaasha ay dhacdo in tani ma aha waxa ugu wanaagsan. burada mar kale u muuqan kara dhawr sano ka dib, oo ay ku jiraan ka dib markii guul laga gaaro daawayntaada. Noocan ah saamaynta in daawo loo gudbiyaa waxyeelo goor danbe. Taasi waa sababta dhammaan bukaanada aan marka laga reebo, ka dib markii koorso of therapy waxaa lagula talinayaa in ay si joogto ah dhakhaatiirta arkay.

tallaabooyinka ka hortagga

Dhakhaatiirta ma siin wax kasta oo talooyin gaar ah u tahay ka hortagga horumarinta dabiiciga ah malignant burada iyo sidoo kale sababaha ay formation ayaa weli si xun fahamsan yahay, marka laga reebo cabista u maleeyeen dhaxlo. Haddii qaraabada dhow waligay la hornimaadno this laga helay inta lagu jiro qorshaynta uurka ka qabtaan waa la jecel yahay in ay ka qayb galaan wada tashiga ee geneticist doctor-. waxay u badan tahay in ay caawiyaan looga fogaado rabshado mustaqbalka la xidhiidha dhalashada ilmaha aan caafimaad qabin.

Nasiib darro, kansarka ayaa haatan sii kordheysa ogaadaa in bukaanka dhallinyarada jiro neuroblastoma marka laga reebo in carruurta. cudurada Photo waxaa laga heli karaa buugaagta caafimaadka gaarka ah tixraac. Hababka gaarka ah ee ka hortagga, dhakhaatiir ma bixin karo sababta oo ah cudurada etiology cadda. Marka astaamaha aasaasiga muujinaya cudurkan, waxaa muhiim ah in raadsatid la-talin caafimaad. Kaliya ka dib markii ay marayaan qiimeyn dhameystiran ogaanshaha xukumi kara qof ee burooyinka iyo in la sameeyo istiraatiijiyad daaweynta lagu dayan karo. khabiir hore xaqiijin doona ogaanshaha kama dambaysta ah, si fiican fursadaha soo kabashada buuxda. Joog caafimaad!