Metastases Bone.

Mid ka mid ah dhibaatooyinka ugu waaweyn ee kansarka oo dhan - bilawga lama huraan ah heerka ugu dambeeya - marxaladda of metastasis. Axdigu metastasis waa neoplasms malignant in socodka ah dheecaanka ama dhiigga waxaa laga diiwaan geliyay xubnaha fog iyo unugyada, kuna waari dhexdeeda bilaabmaa si ay u horumariyaan geeddi-socodka neoplastic.

Kansarka dhammaan xubnaha iyo unugyada waxa laga yaabaa metastasize ilaa lafta. lesions noocan oo kale ah waxaa laga heli karaa ku dhawaad kasta oo qaab-dhismeedka lafta. The ugu badan - metastases in dhabarta, ugu yaraan in ay miskaha, feeraha iyo addimada.

Maxaa burooyinka metastasize in lafta?

Inta badan, habkan waxay dhacdaa marka kansarka qanjirka thyroid, prostate iyo Qanjidhada caanaha.

Waxaa jira laba nooc oo asaasi ah nidaamka bahal ah ee lafta - metatstazirovanie osteoblastic iyo osteolytic. Waayo, foomka shaabadda koowaad waa caadiga ah unugyada lafuhu, gaar ahaan ka kooban macdanta ay. Foomka labaad ka caawisaa "dhaqo baxay" oo ah macdanta, oo ciday weeyaan khafiifinta iyo jab.

pathogenesis cudurka waxanu waa wixii wuxuu kobciyaa unugyada burada. Haddii metastasis kansarka ku lug osteoblasts ee geedi - foomka osteoblastic soo koraya. Marka burada ugu horeysay ee ay jidka la kulmay laf resorbing unugyada (osteoclasts) - waa formation of metastases osteolysis.

Xaaladaha intooda badan, muuqaalka kore ee metastases ee lafta sababa xanuun la soo dhaafay. Xanuun syndrome waxaa keena dhaawaca ku dhammaato dareemayaasha koritaan buro, korodhka cadaadiska gudahood lafta ah, oo ay sabab u dhammaato cuncun macdantaa dareemayaasha qoondeeyey walxaha metastasis. Intaa waxaa dheer, xanuunka wuxuu dhacaa marka jab lafta sababa khafiifiya of dhaafay (caan ku foomamka osteolytic) ah. Si ay u sameeyaan hypercalcemia osteoblastic sifo muujiyay (calcium dhiig oo sareeya).

Khatarta oo jab ah waa jaaniska sare ee dhibaatooyinka - lungemboli, thromboembolism xididka qoto dheer (dambeyntii, tani waxay keenaysaa in khasaaraha ka mid ah xubnaha functional loading ama addinka oo meelmar ah).

metastases Bone laga helaa isticmaalaya X-ray. Ujeedada this, isticmaali raajada Caraabaah ee badnaanta a of lesions xadka-, iyo sidoo kale qaab osteolytic. In the case of osteoblastic qaadeen baaritaano radionuclide. Mid ka mid ah hababka aqoonsi, taas oo loo arki karaa metastases lafta kaliya ma, laakiin sidoo kale xubnaha kale iyo unugyada - PET 18P-deoxyglucose.

daaweynta Qalliinka ee metastases lafta lagu muujiyay at jab la soo dhaafay ay suurtagal tahay. qalliinka lafaha sameeyaa qaliin si loo xoojiyo lafta by musmaarradii galinta iyo buuxiyo booska la buro shamiinto laf.

Dawaynta ilayska ee dose ah oo ku saabsan shan iyo toban - shan iyo labaatan Gy (u sabab ah afarta jajab), nus ka mid ah bukaanka waa ka lumay xanuun. Qiyaasta soddon - shan iyo afartan Gy keena horumar weyn oo xaalad ka mid ah bukaanka, gaar ahaan horumarka sida horumariyo badan gaadhista xiga laba - saddex toddobaad.

qaab labaad oo ka dambaysay Dawaynta ilayska, waa isticmaalka strontium shucaaca. Waxaa hadda loo daaweyn bisphosphonate. Tani acids gaar ah in la xakameeyo dhaqdhaqaaqa ee osteoclasts. Intaa waxaa dheer, daawooyinka, kuwaas oo ku buriyaan darnaanta xanuunka ee jabka lafaha, iyo sidoo kale by horumarinta burooyinka.

Sayidka, saadaasha ah ee metastasis lafta kala duwanaan karaan, taas oo ku xidhan deegaamaynta ee osteblastnoy ama osteolytic foomamka iyo hababka daaweynta.