Daawada 'Manini': tilmaamaha loo isticmaalo

Diyaarinta "Mannino" diiwaanka qeexayaa daroogada antidiabetic sida wax ku ool ah in diiwaanka INN (International noocan Names) magiciisu yahay "Glibenclamide". walax Tani waa xoog ugu muhiimsan ee diyaarinta ah, kaasoo lagu soo saaro by saarayaasha qaab kiniin, oo miisaankeedu yahay 1.75 mg ama 3.5 mg. Halabuurka The daroogada sida xeryahooda kaabayaal ah ayaa sidoo kale waxaa ka mid ah laktosmonohydrat lactose, silica, cunto daro E 124 - dheeh cochineal, istaarijka baradho, gimetelloza.

The guryaha pharmacokinetic daroogada in Glibenclamide - walax weyn ee firfircoon - waxaa ku jira samaynta qaab micronized. Tani waxay suuro gelineysaa in la kordhiyo heerka wax lays of daroogada iyo kordhiyo aagga of ay soo nuugid. Sidoo kale, nuugista wax ku ool ah qaybaha daroogada methylhydroxyethylcellulose ka geysta, taas oo ah qayb ka mid ah diyaarinta "Mannino".

Tilmaamaha loogu isticmaalo warrami in daro ku lahaa gebi ahaanba saameyn ah kuma laha gobolka ee jidhka, laakiin, si kastaba ha ahaatee, waxay fursad arrin si weyn u kordhiyo waqtiga joogitaanka of qaybaha daroogada ee marxaladda kala firdhay, ugu wax soo saar leh, waayo, falalkiisa. Inta lagu jiro wejigan fiirsashada of daroogada ee qaybaha plasma kordhiyaa saddex ilaa shan jeer, sidaas waxaa jira hoos u dhac weyn in xaddiga glucose.

Medicament "Mannino" calaamad labada guide waxay ka dhigan tahay adigoo guriga si degdeg ah nuugo ka soo mareenka caloosha iyo mindhicirka iyo qaabka micronized of Glibenclamide awood u gebi ahaanba la sii daayay ka xeryahooda kaabayaal ah ee jirka ku jira shan daqiiqo. saamayn Tani waxay suuro gelineysaa in ay qaataan daawada hadhuudh ah wax yar ka hor, 5 - 10 daqiiqo ka hor. fiirsashada ugu sarreysa wuxuu dhacaa diyaarinta hore, oo ay tallaabo, sidaas daraaddeed, waa nafsaaniga ah. Inkasta oo mabda ', soo dhaweynta isku mar oo cunto ah ma saamayn badan ku tallaabo ah ee daroogada haysan. Diyaarinta "Mannino" ayaa heer ah 100% bioavailability. Its bar-nolosha ee u shaqeeyo waa qiyaas ahaan hal iyo badh ilaa seddex saacadood iyo badh.

Time saamayn deggan hypoglycemic of Glibenclamide la hayo maalintii oo dhan.

The guryaha pharmacodynamic of daroogada, "Manini" diiwaanka qeexayaa sidan. Medikamet Taasi waxay hagaajin laga yaabaa in dheecaan ee insulin markii nuugid ka unugyada beta beeryarada, iyo daroogada oo horumarinaayo dareen insulin, oo waxaa lagu gaarayaa by kicinta ee receptor insulin ah.

Intaas waxaa sii dheer, Glibenclamide waa inay awoodaan inay yareeyaan tallaabada of dhiig xinjirowga hortago ischemia myocardial. daroogada ayaa sidoo kale waxa uu leeyahay tallaabo ka hortag ah ka gees ah garaaca wadnaha.

Sida waxaa si wanaagsan loo habeeyey, daroogada oon yaraynta halista dhibaatooyin sonkorowga (type 2), kaas oo ka mid ah cardiomyopathy diabetic, nephropathy iyo retinopathy. Daawo "Mannino" diiwaanka qeexayaa iyada oo loo adeegsanayo yareeyo heerka dhimashada ee cudurada la xiriira cudurka macaanka.

Ififaalaha weyn ee isticmaalka Glibenclamide - macaanka nooca labaad, marka therapy cunto tusay natiijo lagu qanci karin. Kiniiniga "Manin" waxaa loo isticmaali karaa sida wakiilka madax bannaan-daweynta, iyo qayb ka mid ah therapy isku dhafan oo daawooyin kale anti-macaanka.

Waa in la dhasha maskaxda ku haysaa in muddada dawada iyo qiyaasta qiimaha ay go'aamiyeen dhakhtarka ku salaysan hab qofka bukaanka. Marka marxaladdan hore ee daaweynta dhigay qaadasho yar oo maamulka daroogada. Markaas, hab la saxo codsiga, si wadajir ah ula edbinta cunto. Faahfaahinta dose mudada lagu faahfaahiyay tilmaamaha loo isticmaalo daroogada.

Faraj ugu weyn ee dose sixitaanka waa heerka glucose.

Glibenclamide Qaadashada keeni karaan waxyeelo, ugu badan ee kaas oo ah hypoglycemia. calaamadaha ay yihiin dhidid lama filaan ah, gariirka, madax-xanuun, xanuunada dareemayaasha, iyo kuwa kale.

Sababo maamulka daroogada waa diidmo in daaweyn jiray qaybaha tayo darida sare leh, ketoacidosis, xanuunada "Mannino" functional ee kelyaha iyo beerka.

Ma jiro macluumaad ku filan oo ku saabsan isticmaalka daroogada reer, kuwaas oo ay da'doodu ka kama badna 18 sano.

Ha isticmaalin daawada inta lagu guda jiro naas-nuujinta iyo inta aad uurka leedahay.

Ku kaydi daawada waa in heerkulka a aan ka badnayn 25 C. In shuruudaha kaydinta nolosha shelf ee daroogada waa 3 sano.