Antibiotic "Maxipime": tilmaamaha loo isticmaalo, analogs iyo dib u eegis

helitaanka antibiotic ugu horeysay (penicillin oo dhan maanta loo yaqaan) ee bartamihii qarnigii labaatanaad ayaa ahayd horumar weyn ee daawo. Inta lagu jiro dagaalkii labaad ee dunida, dawadan badbaadiyey nolosha kumanaan ka mid ah daafacyada of hooyo ee.

Tan iyo markaas, Kiimikada noole iyo wershedaha dawooyinka si degdeg ah horumarinta iyo bixisaa macaamiisha iyo aad u badan antibiotics. Mid ka mid ah ugu horumarsan oo si ballaaran loo isticmaalo beeraha kala duwan ee daawada waa "Maxipime" kaas oo dib u eegis ku nidaaminaya qalab this sida aad, aad u wax ku ool ah waayo kala duwan cudurrada bakteeriyada.

Qaab dhismeedka iyo Curiska

The qayb weyn ee firfircoon ee daroogada tani waa laktosmonohydrat tsefepimadigidrohlorida. Thomas Production - budada ah hurdi cado anfac xal maamulka muruqyada dhexdooda ama xididka xiga. In dhowr qaadashada saaraha bixiyaa macaamiisha ay wax soo saarka "Maxipime." antibiotic waa la iibsan karaa in dhalooyinka dose of 500 mg oo 1 g

Halabuurka The diyaar u ah maamulka lagu kaydin karaa heer kulka qolka hal maalin. Under xaaladaha nolosha shelf qaboojiye ah xalka ugu diyaar u kordhay ilaa 1 toddobaad. In budo ah iyo in a diyaarinta weelka stoppered lagu kaydin karaa muddo 3 sano ah. Shuruudaha - heerkulka si + 30 ° C iyo in laga ilaaliyo iftiin. Beddelidda midabka ah ee xalka uusan saamayn ku lahayn dhaqdhaqaaqa ee daroogada.

saamaynta pharmacological

"Maxipime 'tilmaamaha loogu isticmaalo waa taagan yahay sida wakiilka ah bakteeriyada in iska leh kooxda cephalosporins qarnigan 4-tii. saamaynta mabda'a waa u baabba 'darbiyada unug of nooc bakteeriya. daroogada waxay leedahay qaybaha kala duwan ee saamaynta ee la xiriirta kala duwan oo ka mid ah sheyga Gram-positive iyo Gram-negative, waxaa lagu gartaa in ay iska caabin ah si aminoglycosides iyo antibaktrialnym micnaheedu tahay in kooxdu cephalosporin-qarnigooda saddexaad.

Waayo, "Maksipima" caan ku caabiga beta-lactamases oo firfircoon ka dhanka ah tiro badan oo ah laylinta Gram-positive iyo Gram-negative (liiska Caddaynay - tilmaamaha loo isticmaalo). Laakiin daawooyinka ma firfircoon ka dhanka ah ✰Malax mid metitsillinoustoychivym, penitsillinoustoychivye PNEUMOKOCKER.

Ka dib markii hordhaca ah antibiotic "Maxipime" (diiwaanka ku jira macluumaad sida) ayaa si buuxda u nuugo. Daaweeyn uruureen muhiimka ah ee qayb weyn ee firfircoon yihiin la ogaado in kaadida, xameetida, dheecaanka bronki, qanjirka 'prostate' iyo dheecaanka xuubka hoose.

The bar-nolosha waa qiyaastii laba saacadood. Wixii la barbardhigo, waxaan dhihi karaa in, tusaale ahaan, bukaanada qaangaarka ah kuwaas oo 9 maalmood by xididka helay 2 g of daroogada la bareeg waqtiga u dhexeeya daaweynta ugu yaraan 8 saacadood raasamaal cefepime ee jirka ku jira waa inaan laga helin. Qadarka ugu weyn raaca kaadida (ilaa arkay in 85% oo ka mid ah qaadashada asal helay bukaan cefepime sida beddelin).

Tilmaamayaasha

tilmaamaha bakteeriyada "Maxipime" loo isticmaalo waxaa lagu dhiirigelinayaa inay soo magacaabaan ee noocyada kala duwan ee cudurada of nooca faafa iyo bararka. natiijo fiican yihiin helay in daaweynta cudurada hoose neef-mareenka (pneumonia iyo boronkiitada ay ka mid yihiin) iyo marinnada kaadida (labadaba ma dhib badan, iyo dhibaatooyin ay ka mid yihiin baylonfiritis). dhaqdhaqaaqa wanaagsan lagu arkay daaweynta lesions kala duwan faafa intra-caloosha (ma aha marka laga reebo cudurka marinka biliary iyo peritonitis).

Sidoo kale, "Maxipime" waxaa si balaadhan looga isticmaalaa by xirfadlayaasha caafimaadka ee daaweynta ee cudurada dumarka, cudurada maqaarka iyo lesions unugyada jilicsan, septicaemia (sepsis). In daaweynta bukaannada qaba neutropenia xummada leh, "Maxipime" buuga lagu talinayaa sida daaweynta taaban karo.

Dhinac kale oo saamayn of daroogada - meningitis bakteeriyada ee carruurta. Halkan, antibiotic waxa sidoo kale si fiican u xaqiijiyay.

Iyadoo tallaabo ka hortag ah daroogada loo isticmaalo si looga hortago cudurada ee koorsada of qaliin caloosha.

Guud ahaan waxaan dhihi karaa in "Maxipime" isticmaalka la oggol yahay hoos yimaada oo dhan cudurada faafa, horumarinta taas oo ka xanaajisay nugul bakteeriyada iyo muruq go'a. Si loo ogaado shaqeeyo sababaya ayna go'aansato in (ama) dareen in antibiotic this ayaa la rejeynayaa in uu sameeyo imtixaanka. Si kastaba ha ahaatee, "Maxipime" saameeyaa kala duwan ee nooc bakteeriya iyo in sida monotherapy ah la qaadi karaa xitaa ka hor inta garashada pathogene ah. Haddii ay jirto halis ah in a isku qasan cudurka (laylinta-anaerobic), ka dibna si baaritaano ku saabsan Aqoonsiga bakteeriyada pathogenic bilaabi kartaa daaweynta "Maksipimom" tusmo ahaan daroogada saamayn ku anaerobes ah.

Qadarka Qaadashada iyo kacmaha daawada

foomka qiyaasta iyo Maamulka (w / w ama w / o) waxaa ka go'an ku xiran tahay dareenka ee bakteeriyada, darnaanta gobolka cudur oo ka mid ah bukaanka iyo kelyaha. Iyo jidka I / O waxaa badanaa lagu doorbiday in kiisaska cudurka waa ay adag tahay oo halis ku ah nolosha bukaanka.

Dadka kelyaha caafimaad oo miisaankeedu yahay in ka badan 40 kg irbado sameeyey dura 12 saacadood in qiyaas uu dhakhtarkaagu kuu qoray. Xanuunka of mareenka kaadida fudud si darnaanta dhexdhexaad ah, cudurrada kale ee dhaca xoogga la mid ah, waxaa lagu daaweeyaa in qaadashada of 0.5-1 g, ay maamusho intravenously ama intramuscularly (sida dhakhtar go'aansado). Si loola cudurrada halis ah ku dhaqma intravenously maamula at 2 walax g (periodicity waa isku mid - 12 saacadood). Waayo, mid aad u culus oo ay saarnaayeen ay khatar ku tahay nolosha cudurka bukaanka iyo qiyaasta loo baahan yahay waa 2 g, laakiin periodicity - 8 saacadood kasta saacadood kasta.

Antibiotic "Maxipime" waxaa loo isticmaalaa in hargabka oo keliya, kuwaas oo sidoo kale halkaas oo bakteeriya ku xiran in socodka infakshan fayras.

In koorsada of qalliin (1 saac ka hor) prophylactically intravenously ka badan 2 saac hogaanka g 'Maksipima "ka dibna ku shubay dheeraad ah 500 mg ah metronidazole. Isla maamula laba walxaha maaha.

Celcelis ahaan lacagta daroogada ee bukaanka qaba miisaanka jidhka ah ma uu gaaray 40 kg, in daaweynta cudurada mareenka kaadida (adag oo dhib badnayn), unugyada jilicsan iyo maqaarka (ma bixi waaya), caabuq sambabada iyo therapy taaban karo qandho neutropenic waa 50 mg halkii miisaanka jidhka kiilo. Cirbadaha sameeyey dura 12 saacadood. In meningitis bakteeriyada iyo qandho neutropenic isla 50 mg / kg maamula talinaynaa dura daaweynta u dhexeysa, loo siman yahay ilaa 8 saacadood.

Waayo, bukaanka ka cabanaya aan caadi ahayn dhaxgalka kelyaha, looga baahan yahay inay qabsato dose dayactirka. Antibiotic "Maxipime" description daroogada (qiyaasta ku xiran tahay nooca pathogene iyo darnaanta caabuqa qaadi doonaa uu dhakhtarka xaadirka ah) waxay ku talineysaa in mugga hore ee daroogada in ay qaataan waa la mid tahay sida dadka kelyaha caafimaad qaba, halka taageeraya qiyaasta toosin ku xiran tahay qiyamka ansixin creatine.

bukaanka kuwa ka yeesha "Maxipime" iyo kelyaha lagu, waxaa lagu talinayaa in dhamaadka nidaamka dib u soo gelida dose cusub oo antibiotic loo siman yahay si ay u asalka ah. Tani waa lagama maarmaan, ie. K. Waayo, 3 saac oo dialysis laga saari doonaa jidhka ka 68% lacagta guud ee daroogada "Maxipime" (user ku jira macluumaad this).

Sababo "Meksipima"

Inkasta oo kala duwan oo aad u balaadhan oo ah saamaynta bakteeriyada ka mid ah daroogada this, ma waxay leeyihiin liis dheer oo sababo. "Maxipime" diiwaanka mamnuucayaa dadka qaba diidmo shakhsi si cefepime iyo L-arginine. Sidoo kale, waxaa aan la aqbali karin in la siiyaa bukaanka qaba falcelinta of diidmo degdeg ah benisiliinta, wakiilada kale ee beta-lactam, antibiotics sida cephalosporin.

Dhegaysta inuu xaaladdaada caafimaad inta lagu guda jiro daawaynta "Maksipimom" waa in lagu daweeyo haweenka uurka leh iyo hooyooyinka kalkaalinta, dadka qaba cudurada of mareenka dheefshiidka, gaar ahaan cudurada sida kolit ama ulcerös antibiotic-xiriira, enteritis gobolka.

Sida for saamaynta on function taranka, waa in la sheegay in tijaabo on xayawaanka jirin waxyeello ka soo gaartey hooyada iyo ilmaha caloosha loo aqoonsaday. Si kastaba ha ahaatee, waxbarashada iyo sidoo kale ay gacanta ku saamaynta jirka qof dumar ah ayaa waxaa fuliyey. Sidaa darteed, haweenka uurka leh waa la aqbali karo "Maxipime" oo kaliya ka yar kormeer caafimaad. In naaska aadanaha daroogada caanaha la sii daayo tiro aad u yar, laakiin aan halista. Inta lagu jiro mudada nuujinta waa in ay qaataan daawada si taxadar leh.

Intaa waxaa dheer, antibiotic "Maxipime" Buuggan ku talinaysaa in la isticmaalayo taxadar badan kuwa ku xanuunsado daran renal failure raaga. Daraasado ayaa muujiyey in bukaanka qaba failure kelyaha chronic kordhay bar-nolosha oo ah walaxda jidhka ka. Isla mar ahaantaana, dadka qaba cudurka beerka, ama cystic fibrosis aan dareemay by wixii isbeddel ah pharmacokinetic ay sabab u tahay nuugista iyo Digo of cefepime.

Dhibaatooyinka ay keento, xad-dhaaf ah ee qiyaasta la ogolaan karo

Guud ahaan waxaan dhihi karaa in "Maxipime" si fiican loo dulqaatay, iyo dhacdooyinka dhacdooyinka xun ma aha sare. Dhammaan xaaladaha inta badan waxay ahayd abbaaraha shaqaynaya oo ka mid ah cudurada dheefshiidka mareenka (dyspepsia, shuban, calool, lalabo, matag), iyo jawaab diidmo (finan, cuncun, xummad).

Intaa waxaa dheer, macluumaadka laga heli karaa daroogada this sida an "Maxipime" antibiotic - sharaxaad ku saabsan diyaarinta, tilmaamaha loo isticmaalo, - caddeyn ah suurtogalnimada uu cadaanyo ba'an ku saabsan qayb ka mid ah nidaamka wadnaha qaab tachycardia (wadno) iyo xabad xanuun. neefsashada laftiisa sheegi kara dhuun xanuun, neefta oo ku qabata iyo qufac. The jawaab u badan tahay ka yimaada habdhiska dhimirka noqon doonaa hurdo la'aan, madax xanuun suurto gal ah, dawakhaad, walaaca, wareer, paresthesia. Ka mid ah daliilka kale oo aan ka hadli karaa daal, vaginitis, dhidid, xanuun, dhabar xanuunka, bararka durugsan. Sidoo kale, sida dhibaatooyinka soo raaca ee xirfadlayaasha caafimaadka ka hadlaan isbedel ay suurtagal tahay in xuduudaheedu shaybaarka.

Sida impermissibly si ay u helaan qiyaasood ee buuga "Maxipime" edbinta antibiotic wargelinaysaa oo ku saabsan waxtarka of kelyaha sifeeya kiisaska noocaas ah.

Maxay waa in aad lacag bixisid si aad fiiro?

Miisaanka of xaaladaha aan caadi ahayn oo kala duwan waxaa laga yaabaa in inta lagu guda jiro muddo markii qoray antibiotics "Maxipime." Sidee loo codsan kiiskan? Haddii asalka ah "Maksipima" horumariyo colitis pseudomembranous shuban dheer, joojiya eyniga oo dhan loona maamulay vancomycin ama metronidazole.

Haddii bukaanka xanuunka beerka iyo kelyaha ba'an marka la isku daro failure, shaqaalaha caafimaadka waa in ay la socodka joogtada ah ee fiirsashada daroogada ee plasma dhiigga iyo, ku xiran tahay xuduudaha, qabsato qiyaasta.

Haddii antibiotic ayaa diyaar u ah muddo dheer, waxaa muhiim ah in si joogto ah loola socdo oo sideeda oo dhiig durugsan iyo tilmaamayaasha functional of kelyaha iyo beerka.

Mararka ay bukaan ka ah faafa diiradda fog arkay faafinta meningeal (faafidda jeermiska, labada gudahood qoryaha, iyo dhammaan jirka), waxaa jira shaki ah meningitis ama cudurka uu mar hore lagu rakibay, waxaa lagama maarmaan ah inaad diido daaweyn "Maksipimom" oo ku meeleeyo kakoe- ama wakiilka bakteeriyada kale la oggolyahay lagu ogaado xaqiijiyay.

Waxaa suuro gal ah in la aqoonsado ficil celin qabitaan ah imtixaanka Coombs ', been-positive - in joogitaanka glucose kaadida.

"Maxipime" oo ka mid ah hargabka iyo qabowga (i.e. in infekshan fayras keeno) ma noqon doonto wax ku ool ah.

Dhexgalka waxyaabaha kale ee

Haddii bukaan-socodka waxaa loo xilsaaray in ay helaan "Maxipime" codsiga isku midka ah ee daroogooyinka kale waa in ka yar kormeer caafimaad. antibiotic Tani ma aha pharmaceutically la jaan qaada dawooyinka kale antimicrobial iyo heparin.

Embriyaha dheecaan Bude cefepime ku ool ah hoos u dhacay marka la diuretics, aminoglycosides iyo polymyxin B. The tusmo kordhay PM-fiirsashada isku mid ah "Maksiprima" ee serum dhiigga kordhin doonaa ilaa horumarinta nefronekroza nephrotoxicity isku daro. Intaa waxaa dheer, in la kordhiyo bar-nolosha.

Isku "Maksiprima" la NSAIDs (daawada anti-bararka non-steroidal) hoos u dhigi Digo ee cephalosporins ee jirka iyo waxay keeni kartaa dhiig-bax.

Isticmaalka isku dhafan oo antibiotics kale bactericidal (aminoglycosides) waxay keeni doontaa in muujinta YAQINSAN, la bacteriostatic - iska soo horjeeda.

daawooyinka analogues

Medicaments analogs la qayb weyn ee firfircoon soo xulay oo ku salaysan magaca caalamiga noocan ah (INN), halkan (for "Maksipima" taasina waa cefepime). The dhigooda ugu caansan wakiilka bakteeriyada comments "Maxipime" ka khubaro ku xusan daawooyin sida "Cefepime-Alpes", "Cefepime", "Movizar", "maxicef" "Cefepime oo Nadiif ah."

Tani ma aha liis dhamaystiran, iyo sida magaca "Cefepime" ah, halkan, marka lagu daro kor ku xusan, waxaa weli jira "Cefepime-Vial", "Cefepime-Agio" "Cefepime-Dzhodas" "Cefepime-Alkema," "Cefepime hydrochloride ".

Sidoo kale noocyada kala duwan ee cudurrada bakteeriyada bixiyayaasha daawo si aad u hesho "Ladef", "Efipim", "Kefsepim", "Tsefomaks", "chainsWe".

Iyadoo la tixgelinayo daawooyinka facooda, waxaa laga yaabaa in aysan mar kasta noqon sida wax ku ool ah sida daroogada shati.

Opinion bukaannada iyo shaqaalaha daryeelka caafimaadka

Tan iyo daroogada uu leeyahay tiro balaadhan oo ah codsiyada in kala duwan ee cudurada microbial, ka dibna opinion oo ka mid ah "Maksipime" jiro jihada wanaagsan, iyo kuwa taban. Dadka intooda badan qaadan antibiotics, way ku qanceen natiijada. Hagaajinta caafimaadka, xataa in noocyada halista ah ee cudurrada bakteeriyada ka dhacay 2-3 maalmood laga bilaabo bilowga ah ee daaweynta. Sida laga soo xigtay shaqaalaha caafimaadka, sidoo kale daroogada ayaa la xaqiijiyay in noocyo kala duwan oo xaaladaha caafimaad. Iyo qiimaha daroogada sidaas ma aha mid aad u sarreeya (waxaa jira daawooyin ka jaban, laakiin waqti isku mid ah, waxaa jira aad uga qaalisan tahay "Maxipime").

Si kastaba ha ahaatee, ma jiraan opinion si niyadsami ah oo ku saabsan daroogada. Badanaa comments negative in kuwa bukaan ah kuwaas oo isu muujiyey in koorsada waxyeellooyinka daaweynta. Intaa waxaa dheer, ra'yiga xun waxaa ka muujiyeen koox gaar ah oo dad ah kuwaas oo qaadan antibiotics "Maxipime" for hargab. Inkastoo ay dhacdo in this natiijadu waa, sidaas si la hadasho, la filayo. Kasta oo qabow waa dabeecadda a viral, iyo "Maxipime" - germicide ah, mabda'a ah kaas oo ku salaysan yahay saamaynta burburinta xuub gacanta of bakteeriyada ah.

Iibso dawo kaliya loo isagoo karo warqad dhakhtar. Oo ku habboonayn in si: takhtar aqoon iyo waayo-aragnimo gaar ah, si ay doortaan antimicrobial iyo xisaabiyo qiyaasta ugu yar ee wax ku ool ah, in dhammaan khataraha waxyeelo waxaa la yareeyo iyo saamaynta togan on jidhka la gaarsiiyaa doonaa.