Syndrome Paraneoplastic sida ay calaamad u yihiin kansar

Sida laga soo xigtay kansarka tijaabo ah, buro waa cudur kaliya, dhaca si isku mid ah in dhammaan xubnaha boqortooyada xayawaanka. etiology ee kansarka, iyo sidoo kale ay pathogenesis aan weli si buuxda u fahamsan yahay by saynisyahano, laakiin xilligaan la joogo waxaa jira 4 aragtiyaha oo waaweyn:

1. Viral. Sida laga soo xigtay in ay, guryaha kansar qabto fayraska qaar ka mid ah: virus Epstein-Barr, virus herpes, virus papilloma, iyo kuwa kale.

2. Physico-kiimikada. Doorka ugu muhiimsan ee horumarka buro kansar qabtaan kiimikada (3,4-benzpyrene, metabolites iyo acids amino TIR SADDEXAAD, Aflatoxin et al.), shucaaca Ionizing.

3. dizontogeneticheskie: neoplastic geedi socodka kac ka unugyada Bookmarks sax ahayn inta lagu jiro xilligii embriyaha.

4. Mixed - beenisay buro monoetiologichnost.

daliilka burada

Symptomatology geedi socodka oncological ee jirka waxaa loo kala saaraa galay calaamadaha hoose iyo guud. muuqaalada hoose waa caddayn toos ah buro, laakiin inta badan muuqan dambe guud, xiriirka la leh burooyinka saamaynta fog on xubnaha bartilmaameed ama habka difaaca niyad shaqo gaba. calaamadaha noocan oo kale ah lagu daro in loogu yeero syndromes paraneoplastic. Waxay waxaa lagu gartaa la'aanta ee isgaarsiinta saamaynta maxalliga ah ee iska caabin ah buro in therapy, horumarinta oo kaliya haddii ay jirto kansarka iyo baaba'aan marka daaweynta xagjirka ah. Tani waxay u ogolaaneysaa for ogaanshaha kala duwan ee PNS cudurro systemic madax banaan.

pathogenesis ee PNS

Tan iyo paraneoplastic syndrome uu yeesho buro shaqaynaya ama ay metastasis, pathogenesis syndrome kasta la xidhiidha xanuun dheef ama nidaamka falcelin difaaca. Sidaas daraaddeed, burooyinka ugu waa nooc ka mid ah "dabinka" for nafaqooyin (vitamins, glucose, acids amino, subaga), sababta oo ah waxa uu yeesho xumaanshaha of unugyo badan oo cachexia guud. Sidoo kale, joogitaanka cudur isku mid ah in unugyada atypical iyo keenaysaa in jawaabta difaaca cross-caadi ah ay sabab u tahay taas oo unugyada caadiga ah dhaawacan ama maligniziruyutsya. buro A kacday ku salaysan unugyada hormoonada jidhka soo saaro hormoon oo dheeraad ah. Xaaladdan oo kale, paraneoplastic syndrome dhici salaysan doonaa ilaaliya yareeyo u nuglaanta si receptors hoormoonada oo sii xumaanaysa cudurada dheefshiidka.

qaar ka mid ah PNS

The burooyinka ugu badan yihiin burooyinka unugyada hormoonada jidhka ah. In xiriir this jiro ah syndrome paraneoplastic hormoonada jidhka. Muuqashadiisa waa fiirsashada kordhaysa oo ah hoormoonka ee dhiigga iyo ilaalinta xitaa ka dib markii resection qanjidhada ay soo saara iyo dheecaan hoos u dul saarin burada.

Articular syndrome teedu sida osteoarthropathy hypertrophic, arthropathies kartsinolidnoy, gouty arthritis, polyarthritis. Tani syndrome paraneoplastic inta badan ka horreeyaa cudurka of burooyinka iyo kor u xitaa ka hor ogaanshaha kansar.

Hematological iyo syndromes dareemayaasha leeyihiin dabcan ugu daran iyo dhimasho degdeg ah. U muuqataa in la beddelo kooban taranta iyo tayada dhiigga iyo neuropathy, taasoo keentay in isbedel organic karin in unugyo ka.