Syndrome nephrotic: Sababaha, muuqaalada clinical, daaweynta

Nephrotic syndrome isku daraa set oo ah calaamadaha, kuwaas oo muujiyay in Digo borotiin laga helo kaadida ee xaddi badan (proteinuria), shiid la egyahay aan caadi ahayn, elektrolytka. khasaare badan oo borotiin laga helo kaadida, hypoproteinemia keenaya, taasoo keentay in godadka dareeraha iyo unugyada, bararka dhacaan.

Sababaha nephrotic syndrome

Waxaa jira cuduro badan oo u horseedi in ay dhacdo ee nephrotic syndrome. Aqoonsaday laba nooc oo nephrotic syndrome: aasaasiga ah iyo dugsiga sare. Foomka ugu horeysay oo horumarsan cudurada kelyaha: glomerulonephritis, amyloidosis, kelyo xanuun interstitial. foomka labaad waa syndrome ah uu yeesho cudurada systemic (vaskulitis, lupus erythematosus, scleroderma, iwm), kansarka, cudurada raaga, ayaa muujiyay dareen diidmo oo xasaasiyadeed oo cudurka daroogada. Dhammaan oo ka mid ah cudurada kor ku xusan asal ahaan leeyihiin aan caadi ahayn in habka difaaca jirka. Under saameynta ay ku antibodies factor sababaha soo saaray iyo kaxeynayo difaaca waxaa loo shubo ee xubnaha ka, oo ay ku jiraan kelyaha.

In loop gaddoonka caafimaad glomerular kelyaha ee nephron waa nooc ka mid ah filter in maraa walxaha lagama maarmaanka u ah in xididada jirka, iyo daahiyaan waxtar leh, oo ay ku jiraan borotiinada. Sidaas darteed of cuduro gaar ah, oo yaraada awoodda qubaan, kordhinta ay permeability in u taagoo ballaaran, ay ka mid yihiin borotiin. Tani waxay sababtay khasaare weyn oo protein in syndrome ee nephrotic. Sababtoo ah proteinuria weyn hoos u cadaadiska osmotic ee plasma ah, waxaa jira hypovolemia, hoos u qulqulka dhiigga xubnaha, oo ay ku jiraan socodka dhiigga kelyaha. Decrease ee socodka dhiigga kelyaha keenaysaa in wax soo saarka sii kordhaya ee aldosterone, renin, Digo sodium waa Kobocii iyo dheecaan ku dhacaa jidhka. All isbadaladan la isku daro in nephrotic syndrome.

Eebbe nephrotic syndrome

Nephrotic syndrome, calaamadaha ay la mid cudur oo kala duwan yihiin. On jirka bukaanka loo arki karaa barar weyn, badala ee maqaarka iyo xub-axaleedka of dystrophic. dheecaan ayaa lagu arkay ma aha oo kaliya in unugyada laakiin nabarrada godadka: pleural, xuubka hoose, pericardial. Xaaladaha daran, barar maskaxda yeesho retina rugta. Nephrotic syndrome waxaa sababa iyadoo ay sabab u ah ee cudurka kelyaha la xiriira waxaa laga yaabaa in la hypertension. By calaamadaha kor ku waafajiyaan qaababka ugu muhiimsan ee cudurka inta ay biirsaday.

Baadhista xanuunada

Aqoonsiga nephrotic syndrome ma aha dhib badan. dhiig ayaa ahaa hypoproteinemia, Dysproteinemia, giperholiserinemiya. ogaanshaha cudurka sababaya, taasoo keentay in horumarinta bandhig syndrome sidii ay sahan iyo sahan bukaanka, iyo sidoo kale qalab dheeraad ah iyo Hababka. dabiiciga ah ee lesions kelyaha waxaa qiimeeya fulinta biopsy kelyaha ah. In lupus erythematosus oo nidaamsan unugyada LE-gaar ah oo laga helay dhiigga.

Inta badan syndrome nephrotic malignant dhacdaa glomerulonephritis, kelyo xanuun lupus. Natiijada cudurka laga yaabaa in kelyaha chronic.

Haddii ay dhacdo in dabeecadda xaasaasi ah syndrome nephrotic ama cudur daroogada, halka baabi'inta factor ee etiological waxaa suurtagal ah si loo gaaro dembidhaafka muddo dheer ama dhamaystiran daawo.

daaweynta

Iyadoo horumarinta dhibaatooyin daran sida syndrome nephrotic, daaweynta cudurrada taas oo horseeday in ay, waxaa la fuliyay in xaaladaha taagan. Waayo, bukaanka waxaa muhiim ah si ay u dhawraan nafaqo sax ah, loogu talagalay buuxinta khasaaro borotiinka, yareysey qaadashada cusbo.

daaweynta daroogada waxaa ka mid ah isticmaalka diyaarinta hormoon, wakiilada anti-bararka magnyl si loo xakameeyo jawaabta difaaca bahal nudaha maamulo. Waayo, ay ka saareen dareere isticmaalaya diuretics potassium-uubatooyin xunxun. Waxay waxaa loo isticmaalaa in lala maamulka albumin, taas oo kordhinaysa cadaadiska osmotic ee plasma iyo fududeeyaa bixitaanka dheecaan ka nudaha.

Saamaynta daaweynta ku xiran tahay darnaanta iyo dabcan cudurka sababaya.