"Indapamide" - tilmaamaha loo isticmaalo

Indapamide "- daroogada ka tirsan kooxda diuretics thiazide leeyihiin saamayn antihypertensive. Daawo "Indapamide" ayaa tilmaamay in loo isticmaalo in joogitaanka hypertension.

tallaabo pharmacological "Indapamide" daroogada

Guide baaqaday in guryaha pharmacological daroogada la xiriira diuretics thiazide. Gaadhista daroogada awood u eegista hortaagaan "hakiyo" calcium channel kordhinaya barti derbiga halbowlaha ah, ku dheehan jiro hoos u dhac guud ahaan iska caabin dhuumaha ugu sarreeya.

"Indapamide" uusan u beddelmin oo shiid carbohydrate, oo la aqbali karo bukaanada qaba cudurka macaanka, iyo wax saameyn ah kuma fiirsashada of subaga ee plasma. Kiniiniga "Indapamide" caawin yareeyo hypertrophy of ventricle bidix, desensitize derbiyada vascular si norepinephrine iyo angiotensin II, wuxuu kobciyaa ereygu wuxuu ahaa ee prostaglandin E2, yaraynaysaa wax soo saarka ee xag oxygen. Sida caadiga ah daawaynta 5-7 maalintii la saamayn antihypertensive la muujiyey, sii qiyaasta hal inta lagu jiro maalinta.

Pharmacokinetics "Indapamide" daroogada

Guide ayaa sheegay in daroogada lagu gartaa bioavailability sare (93%) iyo nuugista in mareenka caloosha iyo mindhicirka. At heerka of nuugista saamaysaa cunto qaadashada. tirada ugu badan ee daroogada ee dhiiggiisa la abuuray hal ama laba saacadood gudahood ka dib markii qaadashada daroogada qadarkuu of 2.5 mg. Daawada waxaa metabolized by beerka. 60% -80% of maaddadu ay tahay wax soo saarka via kelyaha ee foomka of metabolites, qiyaastii 20% - oo xiidmaha. daroogada waxay leedahay ma cumulating awoodda.

Tilmaamayaasha "Indapamide"

Waxbarashada qoray daroogada ah hoos u cadaadiska dhiigga. Sidoo kale, daroogada waxaa lagu talinayaa in kuwa la joogto dusaya wadnaha.

sababo

"Indapamide" waa u in:

- kordhay dareen in ay, iyo taagayo kale ee group sulfonamide ah,

- anuria,

- hypokalemia,

- cagaarshowga daran ahaan ama kelyaha,

- muddada nuujinta,

- cudurada ba'an ee wareegga cerebral,

- uurka,

- 18 jir (sabab u ah mugdiga ah)

- Maamulka isku mar ah daawooyinka kordhinta muddada QT.

Taxadarka maamula daroogada ay goobjoog ka ahaayeen turqo iyo decompensation diabetes.

Keeneysa oo keeneysa in daroogo "Indapamide"

Guide talinaysaa qaadashada kaniiniga gudaha, ma dareere ah. 2.5 mg (dose maalin walba) waxaa sida ugu wanaagsan loo isticmaalo subaxdii ama galabtii. Marka dabcan 1-2 bisha daaweynta daroogada ayaa keenay saamaynta doonayo daweynta, qiyaasta laguma talinayo in la kordhiyo sabab u ah khatarta kordhaysa oo ah waxyeelo. Xaaladdan oo kale, daaweynta daroogada ee nidaamka hypertension u baahan yihiin in lagu daro wakiilka kale antihypertensive ahayn waa lagu durayo ah. Marka daaweynta laba dose "Indapamide" daroogada antihypertensive isku mid.

badinta

calaamadaha xad dhaafka ah waxaa lagu muujiyey by daciifnimo, xad gudub ku ah shaqada iyo mindhicirka, lallabo, matag, dheecaanka iyo rabshooyin elektrolytka. Xaaladaha qaarkood waxaa laga yaabaa inuu dhaco xad dhaafka ah ee niyad-jabka neefsashada iyo xad-dhaafka ah hoos u cadaadiska dhiigga. In bukaanka qaba cirrhosis of beerka ku dhici kartaa kooma cagaarshowga.

Xaaladdan oo ah qiyaasta xad dhaafka ah waa in la fuliyaa saxo si caadi dheelitirka biyaha-elektrolytka ah: lavage a gastric iyo therapy astaamaha.

dhexgalka

Wanaajisaa saamaynta daawooyinka kale ee cadaadiska dhiigga ee sareeya. Ha lagu biiriyo daawooyinka ay ku jirto diuretics lithium, vincamine, kaliyvyvodyaschie.

Dhibaatooyinka ay keento daawooyinka "Indapamide"

Sidoo kale, sida xaaladaha xad dhaafka ah. Waxaa laga yaabaa in rabshooyin garaaca wadnaha la'aan awgeed of potassium. Sidoo kale, waxyeelo dhici kara tabar, hoos u dhac af ee cadaadiska marka taagan, lalabo, calool xanuun, shuban, qalal, dareen diidmo oo xasaasiyadeed. Marar dhif ah, waxaa laga yaabaa in la kordhiyo turqo, casiraad.