Hormoonnada sii daayo hypothalamic

hormoonnada sii daayo waa neurohormone aadanaha in uu ku dhexsameeysmo xuduntii hypothalamic. Waxay la xakameeyo (statins) ama kicin (liberiny) saarka hormoonada pituitary tropic. Waxaa shidaa qanjidhada hormoonada jidhka ah, oo waxaa jira qawaaniin sii daayo hormoonnada. The qaybo sare ee habdhiska dhexe iyo nidaamka hormoonada ay si dhow u la xiriira sababta oo ah hoormoonka sii daayo.

function hypothalamic

Mid ka mid ah qaybaha muhiimka ah ee nidaamka hormoonada masuulka ka ah wax soo saarka ee hormoonnada - hypothalamus ah. Soo saaray walxaha hypothalamus yihiin hoormoonada ku lug leh geeddi socodka dheefshiidka ee jirka.

In hypothalamus waxaa unugyada dareenka in la hubiyo wax soo saarka ee walxaha loo baahan yahay jidhku u baahan yahay, waayo, hawlaha caadiga ah. Unugyada waxaa loo yaqaan neurosecretory. Ay hawl - si ay u helaan digir in gudbiyaan qaybaha kala duwan ee habka dareemayaasha jirka. xubno Go'doon dhacdaa iyada oo synapses aksovazalnye.

Soo saaray hormoonnada sii daayo hypothalamic, ama sida ay u yeedheen duwan, statins iyo liberiny, ayaa muhiim u ah hawlaha caadiga ah ee qanjirka pituitary ee. By ay dabiicadda kiimikada, iyagu waa peptides. Maaddaama ay falalkooda kiimikada iyo dareemayaasha waa duubis, waxay qaadaa dhiigga ku ag nidaamka hypothalamic-pituitary pituitary ee.

dirka hormoonnada

Ka fiirso hormoonnada sii daayo inta badan si fiican u yaqaan:

• Anada dheecaan ah ee shaqada pituitary - waa a melanostatin somatostatin, prolaktostatine.
• Marqaan - waxaan ka hadleynaa melanoliberine, prolaktoliberine, folliberine, lyuliberine, somatoliberin, hormone thyrotropin-daayo, hormone gonadotropin-daayo iyo corticotropin.

Waxyaabahani, ama halkii qaar iyaga ka mid ah, waxaa lagu si xun ugu abuurtay by kale, ma aha oo kaliya hypothalamus ah (tus, xameetida).

Statins iyo liberiny

hawlaha qanjirka pituitary waa si toos ah ku tiirsan iyaga on. Waxa kale oo ay saameyn ku leh hawlaha ka mid ah qanjidhada hormoonada jidhka durugsan:

• thyroid;
• ugxan in gabdhaha;
• xiniinyaha ragga.

Statins iyo liberiny oo ugu wanaagsan ee loo yaqaan waa:

• dopamine,
• GnRH (lyuliberin, folliberin);
• melonostatin;
• somatostatin;
• tireoliberin.

dheecaan ee farabadan oo hormoonnada follicle-madadaalo of pituitary ee GnRH bixiyaan.

On waxqabad ee antiandrogen ragga ayaa sidoo kale saameyn ku yeelan GnRH, gacan ka kordhay dhaqdhaqaaqa shahwada iyo heerka of libido.

Oo dumarkii neurohormone mas'uul ka ah wareegga caadada, xaddiga hormoonnada kala duwan yihiin iyadoo wajiga of wareegga u.

wax soo saarka ku filnayn of sii daayo hormoonnada inta badan sababa dhalmo la'aan iyo kacsi la'aanta.

Astaamaha u gaarka ah hormoonada

hormone Corticotropin mas'uul ka dareenka walaaca, soo saaray hypothalamus ah. Tani waa arrin kale oo muhiim ah sii daayo, ku simaha lala hormoonnada pituitary iyo saamaynta ay ku qanjidhada adrenal. Dadka qaba la'aanta hormoon this inta badan xanuunsado tan iyo hypertension, iyo yaridu adrenal.

GnRH - hormone ah oo kor saarka ee gonadotropins - sidoo kale wax soo saarka ee hypothalamus ah. Waxaa sidoo kale loo yaqaan hormoon gonadotropin-sii daayo.

hawlaha caadiga ah ee xubnaha taranka ma aan samayn karo aan GnRH. Waa hormone this mas'uul ka yahay koorsada dabiiciga ah ee caadada ah dumarka. Iyada oo uu ka qayb qaadataa meel habka of koriinkedu oo sii daayo ukunta. hormone Tani waxay masuul ka tahay libido (galmada). Marka ay jirto wax soo saarka ku filan oo ah hormoonka by hypothalamus ee haweenka inta badan la horumariyo dhalmo la'aan. Maxaa kale waxaa lagu sii daayo hormoonnada?

somatoliberin

Inta badan si degdeg ah lagu sii daayo carruurnimada iyo qaangaarka. Its feature ugu muhiimsan waa habka caadi koritaanka xubnaha iyo hababka jidhka. From ay-soo-saarka waxay ku xiran tahay horumarka buuxa iyo formation of ilmaha. wax soo saarka ku filnayn ee hormone ka Hypothalamus wuxuu horseedi karaa haleelay xilligii (haleelay xilligii).

Prolaktoliberin

Uu horumarka ugu firfircoon dhacdaa inta lagu guda jiro uurka iyo muddada quudinta hooyada ilmaha ka. factor Tani sii daayo normalizes soo saarka ee prolactin, la xirrira marinnada qanjidhada caanaha.

Prolaktostatin

Prolaktostatin loola jeedaa subclass ah statins soo saaray hypothalamus ah, mas'uul ka yahay Iscelin of prolactin.

By prolaktostatinam ka mid ah:

· Dopamine,

· Somatostatin;

· Melanostatin.

Ay tallaabo weyn ee loogu talagalay xakamaynayaan hormoonnada tropic ah pituitary iyo hypothalamus ah.

Melanotropin-daayo hormone

In geeddi-socodka of Midabka iyo kala unugyada melanin saamayn ku melanoliberin. Waxa uu sidoo kale u dhaqmo on waxyaalaha aasaaska ah ee pituitary DWP ah.

Saameynta dhaqanka neurophysiological. Waxa loo isticmaalaa daawaynta ka saareen dalalka niyad iyo parkinsonism.

Thyrotropin-daayo hormone (TRH)

By hormoonnada thyrotropin-daayo of hypothalamus sidoo kale thyroliberine khusaysaa. Waxay kor u wax soo saarka ee hormoonnada ah thyritropic ku pituitary jilibka.

Ilaa xad yar saamaysaa geedi socodka of prolactin. Thyroliberine kor u fiirsashada of tyroksiini ee dhiigga.

Habdhiska uu saamayn weyn ku habka wax soo saarka ee hormoonnada. Waayo, wax soo saarka ee neurohormones yihiin cell neurosecretory nidaamka sharciyeed masuul ka.

hawlaha aasaasiga ah liberinov

hypothalamic Tani sii daayo hormoonnada. Qabashada howlaha sharciyeed. GnRH caadi hawlaha nidaamka taranka ee ragga iyo dumarka.

Waxay mas'uul ka taranka ee hormone follicle-madadaalo u tahay iyo saameyn howlgalka ka mid ah xiniinyaha iyo ugxan.

component sida lyuliberin, Eebay go'doomiyo saamayn on ugxan, la xirrira macquul fikrad uurjiifka.

Dumarka waa la taag daran nolosha saaxiib, iyo lyuliberin folliberin soo saaray tiro ku filan.

Waxaa sidoo kale jira arrimo la xidhiidha sii daayo share celceliska hypothalamus ah, laakiin ay ku xidhnaantooda unugyada pituitary jilibka pituitary oo aan la bartay.

Agonister sii daayo hormone: daroogada

Sida horeba loo xusay, hormoono, kuwaas oo soo saaray hypothalamus ah. Marka la doonayo in ay kicin ugxan, tusaale ahaan ka hor inta nidaamka IVF, loo isticmaalo agonister ama corticotropin sii daayo analogs hormone. In uu yahay, waxa ay leeyihiin on jidhka saameyn la mid ah sida ay hormone u gaar ah.

Laakiin fursadaha dhibaato on qayb ka mid ah jirka oo dumar ah. Tani waxay dhacdaa ay sabab u tahay heerka estrogen hoose. Saamaynta ugu caansan waxaa ka mid ah:

• madax-xanuun,
• dhidid xad-dhaaf ah;
• dareenka gubashada ah;
• qallayl siilka;
• isbeddelo ah niyadda;
• niyad-jabka.

Daawooyinka waxaa loo isticmaalaa sida soo socota:

• "Diferelin" waa analoogga decapeptide macmal ah hormone dabiiciga sii daayo.
• "Dekapeptil" oo qayb ka ah triptorelin ah, analoogga macmal ah GnRH. The bar-nolosha dambe. Inta badan loo isticmaalo bacrin.
• "Lyukrin saldhig" - leuprorelin. Waxay leedahay anti-estrogen, saamayn anti-androgenic, Caafiya endometriosis, burooyinka hormoonka-ku-tiirsane - kansarka qanjirka 'prostate' ah, fibroids makaanka. "Lyukrin saldhig" yaraynaysaa fiirsashada of testosterone ragga, estradiol dumarka, marka lagu daro, hakiyo incretia pituitary FSH, LH.
• Saamaynta daroogada si tartiib tartiib ah dib u soo celisa dheecaan ka nafsaaniga ah hormoonada.
• 'Zoladex' - analoogga dardaro ee hormone dabiici ah hormone-daayo (LH). Inta badan loo isticmaalaa in IVF. Yaraynaysaa fiirsashada of estradiol ee dhiigga, taasi dhacdo, sababtoo ah xakamaynta of dheecaan LH of pituitary jilibka.
  

Waxaan ka wada hadalnay diyaarinta agonister sii daayo hormone.

Doodeen

Tan iyo markii la helo daayo agonister hormone buu u kordhayaa estradiol dhici kara in la sii daayo kadis ah lamaanayaal farabadan. Tani waxay keenaysaa in ugxantu dhicis ah iyo burburinta ukunta. Si looga hor, Doodeen u sii daayo isticmaalka hoormoonka. Sidaas darteed ee ay falsayeen kicin kara qanjirka pituitary mar kale. Ugxansiduhu hyperstimulation syndrome ma qaaddeen muujin, laakiin waxa ay inta badan waa kiiska ay sabab u tahay isticmaalka daba dheeraaday ee agonister GnRH. Waxaa maamula shan maalmood gudahood laga bilaabo codsiga of hormone dhiirrigelin follicle.

Si therapy waa guul, dhan-Ujeedada diyaar garowga waa in ay ahaataa oo keliya ku takhasusay.