Amyotrophic lateral sclerosis: sababaha, calaamadaha, daaweynta

"Amyotrophic lateral sclerosis" Disease waa cudurada culus organic ah etiology aan la garanayn. Waxaa lagu gartaa lesions ah neurons motor sare iyo hoose, dabcan horusocod ah. Dhammeystay ALS (amyotrophic lateral sclerosis) wariyaasha dilaa. Next, waxaan ka baranaynaa sida loo mariyo cudurada, iyo haddii ay jiraan waa wax macquul ah ee laga takhaluso cudurka.

Guudmarka

amyotrophic lateral sclerosis waxaa loo arkaa cudur aan la bogsiin. Wuxuu saameeyaa habka dhexe ee neerfayaasha. Pathology uu leeyahay qaar ka mid ah magacyada kale: cudurka Lou Gehrig ee, cudurka Louis Gehrig ee, tusaale ahaan. Waxaa cudurka Mar walba ma fududa. Xaqiiqada ah in sanadihii la soo dhaafay si weyn u kordhay kala duwan ee xanuunnada ee daliilka kiliinikada kala duwan lagu arkay cillad lahayn sida, iyo murqaha sclerosis lateral syndrome. Marka tan la eego, khubaro maanta rumaysan saaridda hawsha ugu muhiimsan oo Hadba of etiology cudurka.

Murqaha Lateral Sclerosis: Calaamadaha

Eebbe cudurada la xidhiidha, ugu horrayn, iyadoo soo gaartay oo ka mid ah neuron motor hoose. amyotrophic lateral sclerosis, kuwaas oo astaamaha waxaa ka mid atrophy, daciifnimo, fasciculations, ayaa calaamadaha dhaawac channel corticospinal. Arintaan waa spasticiteten iyo seed kordhay iyo hummaag bahal aan dareenkiisa oo dhiman. Xaaladdan oo kale, ka wadooyin cortico-bulbar laga qayb galin karaa. Tani, markeeda, dardar doonaa horumarinta cudurada heerka of jiridda maskaxda ah. ALS saameeyaa dadka waayeelka ah. Pathology aan korin, ilaa 16 jir.

bandhigayaa muuqaalada

In dadka ka cabanaya amyotrophic lateral sclerosis, marxaladaha hore ee cudurka waa wayn atrophy muruqa (Dabcan horusocod) la hyperreflexia. Habkaani waa muujin caafimaad oo ugu muhiimsan. Pathology bilaabi karaan si ay u horumariyaan oo dhan fiiloyin muruqa striated. amyotrophic lateral sclerosis yeelan karaan dhowr nooc: bulbar, sare, lumbosacral iyo afka ilmo-galeenka-thoracic. Sababta dhimashada, sida caadiga ah, waa guuldaradii murqaha neefsashada ka dib oo ku saabsan 3-5 sano. amyotrophic lateral sclerosis ayaa dhowr muuqaalada sifo. Mid ka mid ah daliilka ugu badan loo arkaa tabar horusocod macdantaa muruqa ah mid ka mid ah jirka sare. Sida caadiga ah, waxa ay ka bilaabantaa gacanta. Iyadoo horumarinta socodka unugyada jidhka leh cudurada proximally amro waa wanaagsan more. Bilowga cudurka la xiriira horumarinta tabar-dari muruq in gacmaha, habka lug thenar macdantaa. Status muujinaysaa adduction tabar (keenay) iyo mucaaradka ah ee suulka. Natiijadu waxay tahay mid dhib badan inay haleelaan suulka iyo farta, dhibtay gacanta motor wanaagsan. Bukaanka qaba ALS dareemaan dhib galinta (guluusyada-down) oo soo gaaray waxyaabaha yaryar. Haddii ay saamaysaa gacanta xukuma muuqan dhibaato marka qoraal, hawlo maalmeedka guriga. foomka lumbosacral loo arkaa xad wanaagsan.

cudurada caadiga ah, waayo,

Xaaladdan oo kale waxaa jira mid xasiloon, horumarinta geedi socodka ee muruqyada addinka isku. Later waxaa bilaabay inuu faafin on gacanta labaad in laga adkaado fiiloyin bulbar ama lugaha. amyotrophic lateral sclerosis bilaabi laga yaabaa in muruqyada carrabka, afka, wajiga ama lugaha. Xaaladdan oo kale, burburinta xiga "aan kor u qaadaan" asalka ah. Marka tan la eego, waxaa loo arkaa Filashada ugu gaaban nolosha foomka bulbar ah. Bukaan-socodka dhiman, ka harsan tahay shiidaa on lugaha, ma sugayaan hoose curyaannimo Addinka.

horumarinta dheeraad ah

amyotrophic lateral sclerosis Ulasocto-gaynta kala duwan oo ka mid ah calaamado qallal (bulbar iyo pseudobulbar). Tani advantageously muujiyey dysphagia, iyo dysarthria, oo mar dambe iyo cudurada neef mareenka. Muuqaalka caan ku dhowaad dhammaan noocyada cudurka waxaa loo arkaa inay xoojinta hore ee reflex daanka. Marka liqidda dysphagia cuntada dareeraha ah lagu arkay inta badan ka badan la cunnooyinka adkaha ah. Isla mar ahaantaa, waxaa in la xuso in isticmaalka dambe ee koorsada of faafidda cudurka noqonayaa mid ka sii adag tahay. Waxaa daciifnimo ah in muruqyada masticatory, bilaabataa kaa dhaga dhanxanegga jilicsan, carrabka noqdo Atrophic oo go'an. amyotrophic lateral sclerosis ka bilowdey Ulasocto socodka joogtada ah ee candhuufta, anarthria. Waxa uu noqonayaa mid aan macquul aheyn in la gooyo, waxay kordhisaa suurtagalnimada of pneumonia rajo gelin. Sidoo kale waa in la ogaadaa in casiraad ah (casiraad go'aysa in weylihii) ayaa la soo sheegay in bukaanada oo dhan, oo waxaa badanaa loo arkaa calaamadaha ugu horeeya ee cudurka.

Qaybinta atrophy

waa inaan sheegaa in ay tahay halkii la xushay. At gacmaha bukaanka Hagidda hypothenar soo gaartay, thenar, interosseous iyo deltoids. On lugaha atrophy horumarisa ee meelaha fulinta dorsiflexion. Muruqyada bulbar waxyeelo unugyada ee dhanxanegga jilicsan iyo af. Dunta Oculomotor waxaa loo arkaa ugu adkaysi u atrophy.

galku ku ool ah

In cudurada ee xanuunada dhifka ah iyo endetarms-. Mid ka mid ah muuqaalada cajiib cudurka waa la'aanta ah ee boogaha cadaadiska in curyaanka ah bukaanka jiifay mudo dheer. Sidoo kale waxaa lagu ogaaday in dementia dhacdaa marka cudurka waa mid aad u dhif ah. Marka laga reebo aaminsan yihiin oo kaliya dhowr koox-hoosaadyada: qoyska iyo foomka adag "sclerosis AD parkinsonism-dementia." Ku tilmaamay sida kiisaska ku lug leh dharka hoose ama neurons motor sare. Tani waxaa laga yaabaa in ay adkaan jabiyaan mid ka mid ah aagga. Tusaale ahaan, neuron motor sare dhici kara xoog. Xaaladdan oo kale aynu ka hadalnaa sclerosis lateral hoose. Awoodda dhaawac oo laga dheehan karo ee neurons motor hoose. Xaaladdan oo kale aynu ka hadalnaa perednerogovom syndrome.

rheotachygraphy

Habkani waa gaar ah qiimaha lagu ogaanayo ka mid ah hababka paraclinical waxbarashada cudurka. Isticmaalka EMG waxyooday unugyada baahsan geeska dhaawac jilibka (oo ay ku jiraan in ku kaydsan (Caafimaad ahaan murqaha)) la fasciculations aamba, isbeddel ah ee ku guuleysan kara of unugyada motor, ruxruxo wanaagsan ka dhanka xawaaraha caadiga ah ee faafinta macdantaa excitation ee dareemayaasha dareen ah.

Baadhista xanuunada

Si ay u qabtaan cilmi-baarista si ay u aqoonsadaan cudurada ah, waa in aad haysataa:

• Calaamadaha waxyeellada u neurons motor hoose. Waxaa lagama maarmaan ah, gaar ahaan, iyo EMG xaqiijin badbaadi (Caafimaad) muruqyada
• Calaamadaha waxyeellada neuron motor sare ee koorsada horusocod ah.

Waayo, cudurka waa in ay ahaadaan no:

• xanuunada endetarms-.
• rabshooyin dareenka.
• cudurka Parkinson.
• Visual dhantaalan.
• Bass shabahaya daliilka ah.
• Dementia oo ah nooca Alzheimer ah.
• xanuunada Autonomic.

Cilad waxaa xaqiijiyay fasciculations in 1 ama in ka badan jiidaha, EMG saxiixo xawaaraha caadiga ah ee faafinta dareenka excitation iyo macdantaa motor. Ka mid ah qaybaha waa in la ogaadaa,

• Xafido la ALS. Kiis in dhibic yimaado in la ogaado calaamadaha dhaawac ee neurons motor hoose iyo saddexdii meelaha sare ee jirka.
• Badan tahay. Xaaladdan oo kale, waxaa jira calaamado dhaawaca ah ee neurons motor hoose iyo tan sareba, iyo laba qaybood ee jirka.
• Suurtogalka ah. Dhaawacyada waxaad tustay calaamooyin of neuron motor sare iyo hoose ee hal meel oo jirka ka mid ah ama in la burburay ee goobaha labaad 2-3. Xaaladan danbe waxaan ka hadleynaa daliilka ee ALS ka mid addinka, curyaan bulbar horusocod ah iyo foomka hoose.

Daaweynta amyotrophic lateral sclerosis

Maanta daroogada ugu horeysay oo kaliya loo isticmaalo cudurada, waa hab ka mid ah "Riluzole". Waxaa la ansixiyay Yurub iyo Maraykanka, laakiin in Russia oo aan ka diiwaan gashan iyo in aan la talinayaa karaa dhakhtar rasmiga ah. Daawada ma la baabi'iyo cudurka. Laakiin waa daawada keliya ee uu leeyahay saamayn togan ku cimri bukaanka. medicament The "Riluzole" caawiyaa yareeyo fiirsashada of glutamate (neurotransmitter in habdhiska dhimirka), sii daayay inta lagu guda jiro marinka ee Suu dareemaha ah. xad dhaaf ah xarunta this ayaa laga helay indhaynta falimihiisii kale burbur on neurons-dhabarta iyo maskaxda. Sida ay natiijada waxbarashada clinical ogaaday in kuwa ka qaaday daawada, ku noolaa celcelis ahaan 2-3 bilood muddo ka badan kuwa loo isticmaalo jaallaha ah.

antioksidanter

Tani class xeryahooda nafaqo waxay ka caawisaa looga hortago in dhaawac jidhka oo keeni kara xagjirka lacag la'aan. Waxaa la rumeysan yahay in qofka qaba ALS laga yaabaa in u nugul in ay saameyn xun. Maanta, waxbarashada ayaa socda si ay u aqoonsadaan, ogaado saamaynta supplements faa'iido ku jirto antioksidant. Qaar ka mid ah alaabta, kuwaas oo maray tijaabada, ku guuldareystay in ay caddeyso waxtarka.

therapy saameen

hawlaha kala duwan ee caawin nolosha fudud bukaanka si ay u raaxo badan dhigi. Gaar ahaan, waxaan ka hadleynaa nasashada. Waxaa la rumeysan yahay in Reflexology, udugga iyo massage caawin baabi'iyo stress iyo yareynta walwalka, nasato muruqyada, caadi ah ee dhiigga iyo dheecaanka wareegga. nidaamyada waxay kaa caawin in laga takhaluso xanuunka ay sabab u ereygu wuxuu ahaa ee xanuunka qoomiyadda soo saaray by jidhka iyo endorphins. Ama daawo ama nidaam kasta oo waa in lagu taliyo dhakhtar. In murqaha sclerosis lateral is-daawo si weyn laguma talinayo.