Prostaglandin - waxaa ... Prostaglandins (daawooyinka): qiimaha magaca

Inta geeddi socodka ee jidhkeena ku xiran tahay prostaglandins, kuwaas oo la soo saaray shiidaa unugyada oo dhan. Waxa badanaa la arkaa in ay hormoonnada, si kastaba ha ahaatee, ma ay joogin. Waxay door dhaqmaan goobta of ereygu ka dibna sakhiray si ay u baabba'aan. hormoonnada ayaa sidoo kale saamayn ay ka fog oo ay kala duwanaayeen kaliya by qanjidhada hormoonada jidhka iyo unugyada ma yihiin qaybta ugu.

ereygu wuxuu ahaa ee prostaglandins

Bal aynu eegno formation of walax this ee jirka. Prostaglandin - walax sameeyay inta lagu guda jiro shiid of arachidonic acid, iyagu waa Eicosanoids. acids dufanka leh waa qayb ka mid ah phospholipids, oo waxaa la helay in dhammaan unugyada. Under tallaabada ee phospholipase A2 Geedda acid arachidonic, ka dib markii taas ay soo baxdo on cyclooxygenase ama lipoxygenase dariiqyada. Prostaglandins waa sheyga ee ugu horreeyey.

Waa maxay doorka ee jirka?

Eicosanoids qabtaan noocyo kala duwan oo hawlaha. Prostaglandin - walax in si firfircoon ku lug inta badan geedi socodka ka dhacda jidhkeenna. Tusaale ahaan, E prostaglandin uu leeyahay a depressor saamayn, i.e. yaraynaysaa cadaadiska dhiigga by saameeya midab vascular. Intaa waxaa dheer, prostaglandins (daawooyinka iyo dabiiciga ah) si aad u bilowdo shaqo contractile of myometrium ah, ay sabab u tahay, taas oo ay waxaa loo isticmaalaa xoojiyo foosha. Waxyaabahani waxay kordhin ereygu wuxuu ahaa ee xab oo la soo saaray by unugyada fijaan ee caloosha. Xab qabata shaqo difaac, ka hortagga tallaabada arrimo dagaal on xabka. Intaa waxaa dheer, ay sabab u tahay walxahan waxay u dhigan formation of pepsin iyo aashito, kaas oo wax ku ool ah loo isticmaalo daawaynta cudurada gastric la xidhiidha dheecaan sii kordhaya ee walxaha kuwan. Sidoo kale waxay saamayn ku yeelan guryaha rheological dhiigga, anada xulkii dhiig xinjirowga. Prostaglandin E saameyn unugyada muruqa siman oo ka mid ah dhuunta oo hawomareenno, waxaa kor u nasashada, iyo sidaas, ballaarinta hawo. Doorka muhiimka ah ee prostaglandins in barar iyo xanuun. Waxyaabahani waxay ma aha oo kaliya si toos ah saamayn ku dhammaato dareemaha iyo macdantaa ah, laakiin sidoo kale ay ku lug leeyihiin muuqaalka kore ee calaamadaha kale ee caabuq. Isbeddelka ku oqoonsan vascular hoos tallaabada of prostaglandins taasoo keentay in ciriiriga, iyo in la kordhiyo permeability derbiga - Jidka formation of bararka. Prostaglandins, marka lagu daro saameynta ay tahay on dareemaha vagus, keenaya lalabo iyo matag. Iyada oo sida saameyn liddi ah oo inta badan soo maray by bukaanka. Prostaglandins - daroogada (magacyada hoos) dalban kaliya hoos tilmaamo adag.

Dhexgalka ee prostaglandins iyo daawooyinka anti-bararka

Prostaglandin - waa ka qaybgale toos ah ee geedi socodka bararka. tallaabada of NSAIDs ku salaysan yahay hoos u ereygu (enzyme cyclooxygenase laga xannibo). Isticmaalka muddada dheer ee NSAIDs keenaysaa in la'aanta prostaglandins, taasoo keentay in shaqada kala ooday si daciif ah ee caloosha - hoos u dhac ku dheecaan ee xab. Tani waa weyn oo saameyn ah daawooyinkan.

Prostaglandins - diyaarinta: Magaca

daroogada waxaa loo isticmaalaa ugu horrayn cudurrada caloosha iyo boog malawadka, dabeecadda erosive. Intaa waxaa dheer, ay maamusho si ay u kicin foosha ee myometrium iyo hagaajin rheology dhiigga.

"Misoprostol"

Prostaglandins (daawooyinka) waxaa si weyn loo qaybiyey daaweyn jiray boogaha gastric iyo dyspepsia ay sabab u tahay waxqabad anti-secretory. tallaabo Tani waxay la xidhiidhaa saamayn ku receptors prostaglandin, kaasoo ku yaala unugyada parietal gastric. Sayidka, falalka "misoprostol" sida prostaglandin dabiici ah. Carbinta wax soo saarka xab ka caawisaa ilaaliso xuub-axaleedka iyo ka hortagtaa formation of boogaha cusub. All this abuuraa xaalad wanaagsan ee bogsiinta of boogaha iyo erosions.

"Alprostadil"

Dawadu waa prostaglandin daroogada E. Waxaa sida caadiga ah waxaa maamula in kiisaska korodhka loo baahan yahay in hoos u of myometrium ah - xoojiyo foosha. Sidoo kale, daroogada waxaa loo isticmaalaa si loo hagaajiyo wareegga dhiigga - Iscelin of xulkii dhiig xinjirowga sameeya oo vasodilation (atherosclerosis). Waa la heli karaa in fijaan ee maamulka xididka.

sababo

Labada daroogada aan la maamulay, haddii ay jirto diidmo in prostaglandins iyo analogs dhanba. Ka mid ah sababo ah - 18 jir, uurka iyo nuujinta. Sidoo kale qaataan taxaddar in bukaanka qaba la'aan kelyaha iyo cagaarshowga, heley oo ka mid ah nidaamka hormoonada jidhka, enterocolitis, anemia.

Is-maamulka prostaglandin maandooriyaha adiga oo aan la tashan dhakhtar takhasus u leh lama oggola. dhakhtarkaaga kaliya ayaa ah ka heli kartaa qiyaasta saxda ah iyo qabsato qorshaha daaweynta, iyada oo la tixgelinayo dabeecadaha gaarka ah bukaanka. Waxay ku xiran tahay inaad tegto beddeli doonaa qiimaha. Prostaglandin waxaa laga heli karaa noocyo kala duwan oo ka yar kala duwan magacyada brand, waxa ay sidoo kale saameyn ku kharashka.

waxyeellooyin

Inta badan, marka la qaadanayo daawooyin keeni aan caadi ahayn ee nidaamka dheefshiidka - lallabo, matag, shuban iyo xanuunada dyspeptic. Haddii aad xasaasiyad, calaamadeeyay pruritus, finan, casaan iyo barar, iyo suurto gal ficil-celintan jirka. Maamulka daroogooyinka la xidhiidha laga yaabaa in caadada joogto ahayn, dysmenorrhea. Yaraynta myometrium waxaa inta badan waxa lagu gartaa xanuun caloosha. Ka mid ah waxyeelooyin kale - wareer, madax-xanuun, miisaanka jidhka isbedbedelka.

xaddiga khatarta waxyeellooyinka waa shaqsi bukaan kasto. Marka logu ifafaale sida waa in la xiriir dhakhtarkaaga iyo bedesho qorshaha daaweynta.

Prostaglandin - walax loo baahan yahay in lagu daaweeyo cudurka boog ulcer iyo heley kale. Waxay sida caadiga ah ay weheliso daawooyin kale si loo gaaro tarin. Doorashada daawada iyo qiyaasta ay ku xiran tahay kiiska kiliinikada iyo sifooyinka bukaanka shaqsi.