"Pipekuroniyu bromide": tilmaamaha loo isticmaalo

Daawooyinka lagu nasto murqaha lafaha, hubkaas ayaa loo isticmaalaa ma aha oo kaliya inta lagu guda jiro qalliin ee duration dhexdhexaad ah oo dheer, laakiin sidoo kale in dhaqanka ee dhaawacyada iyada oo ujeedadu of meel bedelka ama kala goysyada bedalay. "Pipekuroniyu bromide" waxa loola jeedaa dabcineyso kooxda antidepolyarizuyuschih iyo muddada ugu badan ee ficil of 50-70 daqiiqo ku xiran tahay sifooyinka ee u shaqeeyo. Ha ka fikiro si aynu tilmaamaha loo isticmaalo daroogada, iyo gaar ahaan isticmaalkeeda ku dhaqanka daawada suuxinta.

soocista pharmacological

hab ay of tallaabo daroogada la xiriira ka xanibeen isu gudbinta synaptic at synapse ee muruqyada. Sababo la this, waxaa jira Iscelin of dhacdo ee ku iman kara talaabada in xuub fiber muruqa, iyo sidaas, unugyada muruqa lumiyo awoodda qandaraas.

Iyadoo gaadhista dheer daroogada keeneysa la "pipekuroniyu bromide" muruqyada lafaha waxay dejineysaa. Marka la eego in receptors nicotinic cholinergic nooca ku yaal ma aha oo kaliya in meesha xiriir macdantaa efferent ku yaal degaaankaaga, habdhiska la unugyada muruqa murqaha lafaha iyo ganglia in habdhiska ku autonomic ah, hordhaca ah ee qaadasho badan oo medicament sababay saamayn ganglioblokiruyuschimi daciif ah. Tan waxa u sabab joojinta gudbinta Suu dareemayaasha in xuubka postsynaptic ee neurons, taas oo horseedaysa hoos u dhac in labada saamaynta garawsi iyo parasympathetic.

Tilmaamayaasha

Diyaarinta "bromide pipekuroniyu" waxa lagu tilmaamayaa for nasashada ee muruqyada lafaha inta lagu guda jiro qalliinka. Waxtarka daawada ujeeddo ah intubation cunaha la hawo farsamo.

sababo

Sida daroogada si uu "pipekuroniyu bromide" edbinta, daroogada waxaa gabi ahaan uu in joogitaanka diidmo oo ay goobjoog ka ahaayeen daweeyay (dhif ah, cudur hiddo goostay, taas oo xad gudub ku ah excitation ee horumarinta muruqyada synapse iyo tabar-dari muruq).

Daawada waa u bukaanka ku jira marxaladaha hore ee uurka. In marxaladaha ugu dambeeya ee daroogada waxaa loo isticmaali karaa, sida ay u soo gudubtaa ka celiyaha mandheerta kaasi oo tiro yar.

waxyeellooyin

Daawada la xakameeyo kartaa waxqabad ee habka dhexe ee neerfayaasha, keeni ifafaale diidmo.

Laga soo bilaabo dhanka waxyeellooyinka wadnaha sababa Iscelin of gudbinta cholinergic at synapses ah. Haddii sidaa la sameeyo waxay yareyn kartaa xaddiga garaaca wadnaha, cadaadiska dhiigga hoose, dhaawac myocardial ischaemic, dhaawac maskaxeed oo la xidhiidha hoos u perfusion.

Markii loo feydo murugada suurto galka ah ee habka neefsashada ah shaqada neefsashada, dhacdo ee xibin gal ama xibin gal (gaar ahaan inta lagu guda jiro aftereffects daroogada).

daroogada ayaa saamayn ku-shiid iyo waa inay awoodaan inay keeni kordhiyo heerka potassium dhiig, sii kordhaya heerka kariyaatiniin qoomiyadda iyo hoose heerarka glucose plasma.

Drug "bromide pipekuroniyu" - tilmaamaha loo isticmaalo

Daawada waxaa maamula oo kaliya iyada oo ay kormeerayaan dhakhtar takhasus u leh. Maamulka daroogada ka hor inta waa loo hubiyo helitaanka anticholinesterases ( "Neostegmina" ama "Pyridostigmine") ama anticholinergics ( "Atropine").

Ka dib markii khalkhalgelinta socodka bukaanka joogto ah waa la fuliyay inta lagu jiro xilliga dib u soo kabashada ka dib markii suuxdinta iyo bukaanka si caadi cabirida xaalada muruqa.

qiyaasta of medicament ku salaysan baaritaan adag oo ka mid ah farsamooyinka shaybaarka falanqaynta bukaanka iyo macluumaadka cilmi baadhista. In joogitaanka failure of function excretory kelyaha, beerka functional failure, cayilka - dose waa in ay ahaataa medicament hoose.

Xalka waxaa isla markiiba loo diyaariyey ka hor maamulka daroogada "bromide pipekuroniyu." Form sii daayo daroogada - fijaan oo ah budada lyophilized ka kooban 0.004 g oo ah walaxda firfircoon.

Waayo, bukaanka qaba dheelitirka elektrolytka dhiigga oo yaraada iyo dheelitirka acid-saldhigga waxaa sidoo kale loo baahan yahay qiyaasta sixitaanka. hoos ahaaneed fiirsashada ra'iyi ee plasma dhiig, hypothermia iyo isticmaalka of glycosides wadnaha (inta lagu guda jiro digitalization) ay awoodaan in ay dheerayn muddada daroogada. In the case of Nasashada murqaha in kooxdan oo ah bukaan hore u baahan tahay inaad caadi elektrolytka dhiigga, ka dibna si ay u fuliyaan Nasashada murqaha. In the case of bukaanka qaba failure raaga wadnaha, wareegga dhiigga u dhigi karaan kordhinta xilliga qarsoon ee saamaynta daroogada (kordhinta wakhtiga u dhaxeeya maamulka iyo bilawga ah ee saamaynta).

Waxaad isticmaali kartaa daroogada ee carruurta laga bilaabo 1 sano. Xaaladdan oo kale waa in la xusuusnaado in jirka ee ilmaha ka yar xasaasi u ah saamaynta relaxant muruqa, iyo sida, si loo gaaro saamaynta ay ku doonay, qiyaasta daawada waa in la kordhiyaa.

daroogada fasax

Qori daroogada for "pipekuroniyu bromide" Cuntadani ee Latin xitaa aan dhigan kartaa dhakhtar. hay'adda Medical helo walxaha awood liiska A kaliya on codsi oo ku salaysan gobolka. In kiiska gaar ah, "pipekuroniyu bromide" Cuntadani waxaa laga yaabaa in kuu qori khabiir ku ah oo isticmaalaya foomka "cas", si kastaba ha ahaatee, ma network isbitaalka oo dhan waxay xaq u leeyihiin xaqiijinta daawooyinka iyo daawooyinka adag, oo ay ku jiraan dabcineyso muruqa.

magacyada ganacsiga

In suuqa dawooyinka daroogada heli karo magacyada ganacsiga sida "Arduan" "Vero pipekuroniyu", "Aperamid", "bromide pipekuroniyu." Magaca ganacsiga daroogada ku xidhan tahay soo saaraha, qeybinayay maandooriyaha ah suuqa dawooyinka.

badinta

xad dhaafka ah ee daroogada iyo saamaynta hoos u suurto gal ah ay sabab u tahay hordhaca ah ee anticholinesterases. daroogada waxay kaa caawin in ay kordhiyaan fiirsashada of acetylcholine neurotransmitter ah, oon ku tartamaya la relaxant muruqyada ah ku qabanaya sites on receptor ah.

Sidoo kale, tallaabooyinka daweynta ee xad dhaafka ah loogu tala galay in la kordhiyo cadaadiska dhiigga, ilaaliyaan hawlaha jidhka muhiim ah, oo ay ku jiraan kharash ku hawo farsamo.

isdhexgalka Drug

Daawada aan lagu qasi karaa xal galiyey kala duwan, marka laga reebo xal isotonic of chloride sodium iyo dextrose. Horumarinta ee saamaynta daroogada caanuhu, qiyaasta wax ku ool ah ku daweyn u korodho hoos xaaladda maamulka lamaguraan in bukaan inhibitors cholinesterase ah.

In codsiga si wadajir ah la relaxant muruqa analgesics maandooriyaha murugada suurto galka ah ee xarunta neefsashada la horumarinta xibin gal, hurdo.

Isticmaalka daroogada la depolarizing dabcineyso muruqa nooca tallaabo kobcin kara iyo daciifin guud ahaan saamayn relaxant muruqa. xaalad Tan waxa u sabab qiyaasta of daroogada, markii maamulka, iyo dareenka shakhsi si daroogada.

gunaanad

Qaadashada Nasashada murqaha lagu jiro qaliinka - qayb muhiim ah oo suuxdinta isku dhafan. Drug "bromide pipekuroniyu" waxa si guul leh loo isticmaalo dhaqanka caafimaad ujeeddooyinkan.

Waa in la xusuusnaado in hordhaca ah ee daroogada ma aha oo kaliya keentaa nasashada ee muruqyada lafaha mas'uul ka ah dhaqdhaqaaqa iskaa wax u qabso, laakiin sidoo kale keenaa qallal oo ka mid ah murqaha-mareenka. this ka fikiraya, daroogada loo isticmaalo xaaladaha iyo qaybaha daryeelka degdegga ah qalliin oo kaliya ka yar.