Daawo A xajiinta - "Kestin". Tilmaamaha loogu isticmaalo

Maqaalkani waxa uu qeexayaa "Kestin" daroogada antiallergic. Tilmaamaha loogu isticmaalo waxa ay la xidhiidhaa kooxda ku xigta clinical-pharmacological: "blockers receptors histamine - H1, wakiilada antiallergic." Daawada waxaa laga qaaday afka, ka dibna saacad waa horumarinta saamayn anti-xasaasiyad. tallaabo Sii ilaa daroogada in laba maalmood ah.

Walaxda firfircoon ee dejinta waa ebastine. Ay ka kooban tahay, halkii kaniini - 10/20 mg, 5 ml - 5 mg. In diyaarinta "Kestin" analogues no.

koorsada daawada waa shan maalmood, laakiin tallaabo ka mid ah metabolites firfircoon ee daroogada la sii for a dheeraad ah 72 saacadood ka dib markii ay dhamaystirka. Dejinaysaa iyo saamaynta anticholinergic waxaa si cad u muujiyeen intii lagu daaweyn "Kestin" diyaarinta: edbinta ku saabsan codsiga ma calaamadee saamaynta ay ku bareeg QT lagu jiro baaritaanka wadnaha ah, xitaa marka la helo 80 dose mg. Marka concomitantly cuntada uu jiro korodh in fiirsashada dhiigga karebastina 1.5 - 2 jeer in saameyn ah kuma laha sifooyinka caafimaad ee daroogada.

Ka mid ah tilmaamo ku saabsan aqbalitaanka "Kestin" tilmaamaha diyaarinta loo isticmaalo waxaa loola jeedaa kuwa soo socda:

• rhinitt xasaasiyad xilliyeed / wareega keena xasaasiyadda: cunto, epidermal, daroogada, manka, iyo kuwa kale;
• urtikaria xanaajiyeen xasaasiyadda xusay iyo sidoo kale saameynta ay qabow, Qorraxda iyo arrimo kale.

Sababo isticmaalka antihistamine loo arkaa waa dareenka sii kordhaya, iyo sidoo kale:

• Uurka / naas-nuujinta.
• Da'da yar lix sano.
• Kordhinta QT-bareeg, hypokalemia, cagaarshowga kelyaha / - loo isticmaalo si taxadir leh.

Inta lagu guda jiray waa siin cabitaanka aalkolada.

Marka la eego daaweynta xasaasiyadda uur buuga "Kestin" edbinta ku qeexan yihiin in aysan waxaa lagu talinayaa in ay sabab u tahay understudiedness saamaynta ay ku this category ka mid ah bukaanka. Sidoo kale, shiidaa oo innaba waxgarasho ma saamayn ay jidhka ka mid ah inta lagu jiro nuujinta iyo awood u leh inay dhex gelin caanaha naaska ee qayb firfircoon ee daroogada - ebastine. Marka la helo in bukaanada waayeelka ah ma jiraan isbedel ku koobin pharmacokinetic.

Qiyaasta: Daawada waxaa la qaataa hal mar maalintii. bukaanka dadka waaweyn iyo carruurta ka weyn shan iyo toban sannadood magacaabi 1 - 2 kaniini. ama 10 - 20 ml of alaabta ee foomka of sharoobada ah. Waayo, carruurta da'doodu tahay 12 ilaa 15 sano, qiyaasta waa 1 kiniin ama 10 ml of sharoobada. Qiyaasta maalin kasta haddii ay taasi ku kordhin kara ilaa 20 mL haddii loo baahdo. qiyaasta loogu talagalay carruurta 6 ilaa 12 sano - 5 mg soo dhaweynta (kiniin ama nus ah ama sharoobada - 5 ml).

Ha ka badan qiyaasta maalin kasta (10 mg) ee wakiilada u xilsaarayo in bukaanka qaba cillad beerka. Xaaladdan oo ah qiyaasta xad dhaafka tilmaamay antihistamine waxaa lagu talinayaa in lavage gastric iyo inay xajiyaan oo ay saameeyeen inta lagu jiro maalinta.

Sida dhexgalka la siyaabo kale "Kestin" tilmaamaha diyaarinta loo isticmaalo waxaa loola jeedaa in uu ballan la rabin isku mar la erythromycin, ketokonazol. Iyadoo daawooyinka soo socda isdhexgalka weyn loo aqoonsaday: "Diazepam" "Theophylline", "cimetidine", iyo sidoo kale coagulants dadban iyo ethanol.

Marka la eego natiijada daawada "Kestin" dib u eegista, inta badan wanaagsan. Bukaanjiifka qaar ayaa sheegaya in markii daliilka qoraxda xasaasiyadda (photodermatitis) iyaguu caawiyaa kaliya qalab. Kale caddeeyo: daroogada this ka caawisaa si ay ula qabsadaan xasaasiyad kala duwan - oo ay ku jiraan liinta, manka, timaha bisada.

Si kastaba ha ahaatee, dib u eegista ay sheegayaan in antihistamine tani had iyo jeer ma saamayn laga filayo. Wuxu leeyahay in ka hor inta aysan "Kestin", waa la jecel yahay in ay gudbaan imtixaanka iyo takhasus u leh la tasho.