Daawada "Tamsulosin": tilmaamaha loo isticmaalo, qiimaha, dib u eegista iyo analogues

"Tamsulosin" antidizuricescoe waa tallaabo daroogada iyo waxaa loo isticmaalaa sida nidaamka ah astaamaha kaadida modulator cudurada urological sababa unugyada-malignant burooyinka prostate qof. hab dareen-celinta waxaa lagu qeexay by hoos u dhac tartiib ah in xoogooda in muruqa siman of prostate, iyo sidoo kale nasashada ee qoorta kaadiheysta. Intaa waxaa dheer, waxaa jira ee doorashada ka xanibeen Alfa kaadimareenka 1A-adrenretseptorov, taasoo keentay in yaraynta dhibaatooyinka soo arkay xirma - cawaaqib dabiiciya oo ah horumarinta adenomas.

Tilmaamo pharmacological ah "Tamsulosin"

Nuugista ee daroogada ah maaddooyinka firfircoon oo mareenka caloosha iyo mindhicirka waxay noqon kartaa ilaa 100%. Experimentally xaqiijiyay in nuugista u korodho marka la qaadanayo kaabsoosha isla markiiba cuntada ka dib. Darajada milmaan saamiyeed si ay waqtiga dhibtu tan iyo isticmaalka daroogada (i.e., waxaa jira a kinetics toosan). fiirsashada ugu sarreysa ee reactants ee plasma ah waxaa ay gaadhin lix saacadood (hal dose 400 mg) ka dib. Si kastaba ha ahaatee, waqtiga this kala duwanaan karaan ku xiran tahay da'da qofka bukaanka ah.

Waxaa la sheegay in soo dhawaynta ee koorsada of shan maalmood, fiirsashada ka mid ah qaybaha ee plasma koror ah by 60-70%. hydrochloride Tamsulosin ku filan si tartiib tartiib ah uu galo habka dheefshiidka: qaadashada Ulasocto formation of metabolites deggan kaas oo ay leeyihiin selectivity sare ee Alfa 1A-adrenoceptor.

Tilmaamayaasha

"Tamsulosin" Buugga barashada daroogada u soocay sida wakiilka ah ee daaweynta ee kelyaha dushooda benign Prostatic, astaamaha daran (adenoma, gubta, iyo cudurka kale ee hoose mareenka xubnaha taranka).

Tan iyo markii ay waxbarashada clinical daaha sow kama ay wax falcelin muhiimka ah ee waxyaabaha kale ee uu sheegay in kooxda dawooyinka, ka dibna ma jiraan xayiraad on codsiga ah ee "tamsulosin" waji ah kaabayaal ah oo la qaxo caafimaad ee doorashada Alfa-1a receptor adrenergic.

qiyaasta lagu talinayo iyo habka maamulka

la'aanta ah ee saamayn hypotensive - muujinta a caan ku daroogada "Tamsulosin". Tilmaamaha loogu isticmaalo wadamada in baahida loo qabo dose doorashada oo keliya ma aha - ku filan oo afka ah maamula 400 micrograms oo daroogada ah ka dib quraacda (2 kaabsoosha / kiniin ah oo miisaankeedu yahay kasta 200 mg, ama 1 kaabsal / kiniin ah oo miisaankeedu yahay 400 mg). Waxaa intaa dheer, heerka this maalin uma baahna in la saxo, xitaa haddii bukaanka uu u arkay leexashooyinkaasi yar ee kelyaha ama beerka. Si kastaba ha ahaatee, bilowga koorsada daweynta waa in uu ka muuqadaa ogaanshaha sax ah si ay u saarayso suurogalka ah ee kansarka qanjirka 'prostate'. Sidoo kale dhammaan inta lagu guda jiro daawaynta waa baaritaanka malawadka khasab ah.

Kaabsoosha iyo kiniiniyada "tamsulosin" waa in aan calyanaqsiga - xadgudub ku ah baqshadda xun u saameyn karto heerka sii daayo oo ka mid ah reagents firfircoon. Isla markii qaadashada daroogada lagu talinayaa in ay biyo ka cabbaan. Waa arin mamnuuc ah in ay isticmaalaan "Tamsulosin" booska la jiifo.

Jira xadeynta iyo sababo

daroogada "Tamsulosin" The, qiimaha kuwaas oo, ku xiran tahay saaraha iyo baakada qaabab, u dhaxeysa 400-1700 rubles, loogu talagalay si gaar ah loogu nin. Sidaa darteed, cilmi-baaris ku saabsan saamaynta ay ilmaha caloosha ku aan la sameeyay inta lagu guda jiro uurka. kaliya qoro waxaa la siiyaa xogta kiniin, in uu yahay, ogaanshaha "kelyaha Prostatic benign" waa in la riday sahanka (with a imtixaanka ka horeeya khasab kansarka).

Ka mid ah contra - diidmo u "Tamsulosin" daroogada (codsiga User waxaa ku qoran liiska faahfaahsan oo dhan reagents kaabayaal ah). Waa aan loo baahnayn in la isticmaalo of yiri wakiilka for hypotension orthostatic iyo cudurada raaga ee beerka ama kelyaha (in kiisaska noocaas ah, dhakhtarka waa in la qiyaaso faa'iidooyinka ka iman kara isticmaalka "tamsulosin" oo loo ogaado inta uu la egyahay saamaynta ay suurto gal negative dabcan a-daweynta).

Iyadoo soo dhaweynta si joogto ah dawakhaad iftiin la ogolaan karo, mararka qaar bedelay gobolka li'i. Darawaliinta Gaadiidka iyo shaqaalaha, kuwaas oo shaqadooda saxafinimo lug halis ah oo dhaawac, waa inaad dhawrtaan oo taxaddar in isticmaalka walaxda.

waxyeellooyin

Like daroogo kasta oo kale, waxaa jira waxyeelo iyo daroogada "Tamsulosin" (qiimaha caafimaadka ragga waa heer sare ah, oo dareen diidmo oo xasaasiyadeed tahay qof yar, si ay dhibaato loo tixgeliyaa sida la'aan weyn waxaa ka mid ah ma loo baahan yahay).

In barbar saamayn bogsiinta qaadan kartaa meeshii:

• madax xanuun,
• cuncun maqaarka;
• duration shuban;
• garaaca wadnaha,
• xanuun miskaha.

"Tamsulosin" Mararka qaar, analogues kuwaas oo si balaadhan looga heli karo suuqa, taasoo keenta bukaan hurdo la'aan ama, taas bedelkeeda, hurdo xad-dhaaf ah. Marar dhif ah - xadgudub ku meel gaar ah ee kursiga oo daciifisa of awoodba.

Iska badinta, daliilka iyo dhexdhexaadnimada

Calaamadaha badinta, taas oo uu noqday natiijo ah oo daroogada waa "Tamsulosin" (tilmaamaha loo isticmaalo digo of this), waxaa lagu dhawaaqaa kartaa ba'an hypotension. Oo in kastoo suurtagalnimada of seenyadan waa mid aad u yar yahay, isku geynta Caawin habase yeeshee sameeyey:

• isla markiiba siiyo bukaan-socodka meel siman,
• haddii loo baahdo, fuliyaan adag oo ah ka mid ah tallaabooyinka loogu talagalay caadi nidaamka wadnaha ee jidhka;
• si loo xaqiijiyo hawlaha kelyaha (qalab la xidhiidha ee aan dabiici ahayn ku saabsanaa isdaahirinta, dhiig shaqayn karto, maxaa yeelay qayb firfircoon waxaa si fiican u la xidhiidha xeryahooda protein plasma);
• keeni matag ee bukaan si ay u joojiyaan nuugista dheeraad ah ee reactants (oo sidoo kale lavage gastric run iyadoo la isticmaalayo isku midka ah ee caloosha jilciya);
• ka maqan oo ka mid ah dhaqdhaqaaqa horumarinta si aad u codsato daawo in kicin wareegga dhiigga.

isdhexgalka Drug: dabiiciga ah ee dareen diidmo ah

"Warfarin" iyo "Diclofenac" tayo saamayn xawaaraha wax soo saarka ee "Tamsulosin" daroogada jidhka ee (qiimaha daroogada badan, laakiin natiijadu waa u qalantaa). Si kastaba ha ahaatee, indhaynta dheer oo ku saabsan isticmaalka wadajirka ah ee daroogada kuwaas oo isbitaalka looma fuliyo, sida natiijo ah, taxadar xad-dhaaf ah waxaa lagula talinayaa. "Atenolol" iyo "Enalapril" ma la macaamilaan ayaa sheegay in wax, "cimetidine" kor u fiirsashada "tamsulosin" plasma, iyo "Furosemide" siinayaa natiijada gebi ahaanba ka soo horjeeda.

Geedi socodka ah ee yareynta dhiig-karka xanaajiyeen by qaadashada of medicament waxaa laga yaabaa in la wanaajiyey ay sabab u tahay isticmaalka waafaqsan of adrenoblokatorovv kale Alfa-1A ama diuretics iyo suuxinta. saamayn weyn ku kinetics pharmacological jajabyada free "Diazepam" iyo "chlormadinone" by diyaarinta "Tamsulosin" diiwaanka (qiimaha kor hab -. 500-1400 xoqin) aan la qeexay.

xaaladaha Kaydinta iyo nolosha shelf

On xaaladaha lagu kaydin jiray oo daroogada ah guide "Tamsulosin" sheegayaa kuwa soo socda:

• kala duwan heerkulka ammaan ah - 15-25 degrees Celsius,
• qoyaan si mug leh - 70%.

Horudhac ah waa wax lagu kaydin jiray ee baakada asalka (meel gaari karin caruurta, kaas oo sidoo kale laga ilaaliyo qorraxdu si toos ah).

Marka dhibcood oo dhan tilmaamaha damaanado soo saaraha in saamaynta ku daweynta "Tamsulosin" ma wiiqi doonto in labadii sano tan iyo markii ay sii daayo.

analogues Drug "Tamsulosin"

Liiska "labanlaabantay" waxaa wakiil laba kooxood oo ka mid ah daroogada. Kooxdu waxay ugu horeysay ka mid ah daroogada, caadi, kii labaadna wuxuu ahaa - a magacyada ganacsiga dhif.

hantida guud:

• "Omnic" (ee asalka ah - Omnic), soo saare - Holland, foomka sii daayo - kiniiniyada / kaabsoosha 10/30 gogo 'halkii pack, kala duwan oo qiimo - 380-1700 rubles.
• "Proflosin" (Proflosin), Germany, finan of 30 kaabsoosha, kharashka lagu qiyaasay - 500 rubles.
• "Sonizin" (Sonizin), wadankaagii hooyo - Romania, xirmo caadiga ah ee 10 ama 30 kaabsoosha, celceliska qiimaha - 450 rubles.

alaabooyinka iyo magacyada ganacsiga ee "Tamsulosin" daroogada kale (analogs in yar caadi ah ama sii daayo foomamka ayaa hore u soo qaaday wax soo saarka):

• "Omsulozin" (Omsulosin), Hindiya, kaabsoosha 0.4 mg (30 kumbiyuutarada.) Safafka Price ka 350 550 rubles.
• "Tamsulosin-Teva" (Tamsulosin-TEVA), "Tamar-Actavis" wax soo saarka shirkadda, Greece, qaabka ka mid ah Baakadaha iyo qiimaha waa isku mid sida in kiiska la soo dhaafay.
• "Tamsulosin-dhex faafiyo" ( "keyd" component sii daayo joogto ah), line-soo-saarka ugu deganaa ee Russia, kiniin 400 mg, kharashka - oo ku saabsan 300-360 rubles.

"Tamsulosin": dib u eegista ah dhakhaatiirta iyo bukaanka

therapy Medical la daroogada this waa guud ahaan guul iyo waxa lagu sheegay in a tibaaxaha dhaca jireenka ah in burooyinka prostate non-malignant.

Ka dib markii 90 maalmood oo ka mid ah calaamadaha hoos ku 2 jeer, iyadoo isbedelka ugu horeysay dareemi waxaa hore u arkay at 14-21 maalmood. Marka la dhameeyo oo ka mid ah calaamadaha dhicistu index by 75% ah (marka la barbardhigo wajiga laga bilaabo), kaas oo sida xaqiiqada ah waa natiijo aan la aqbali karo.

tolerability Beautiful "Tamsulosin" (qiimaha guide iyo dawooyinka ugu badan generic waxaa sare lagaa siin) ka dhigaysa in ay aad u habboon in la isticmaalo marka uu u xilsaarayo bukaanka daaweynta. Si kastaba ha ahaatee, si loo gaaro saamaynta ugu badnaan ka iman karta oo ah walaxda waa ku filnayn, waxaa lagu talinayaa in therapy waafaqsan hababka kale iyo dawooyinka.