4 (free): iska caadi ah. Hormone T4 (free): baaritaanka dhiigga ee hormoonnada thyroid

Of muhiimadda weyn ee hawlaha caadiga ah ee qanjirka thyroid waa nidaam thyroid ka hypothalamic-pituitary. Waxay bixisaa gacanta ku Avv, wax soo saarka iyo waxqabadka hormoonnada thyroid.

Guudmarka

Hypothalamus wuxuu secretes baruurta (tireotro-pin-daayo factor). Waxaa, markeeda, wuxuu kobciyaa ay sii daayo iyo Avv thyroid stimulating hormone (TSH - TTG). TSH ku lug leh geedi socodka la xiriira steroids kale. Gaar ahaan, waxa ay u dareen dheecaan, raasamaal, Dheef iyo Avv triiodothyronine (T3) iyo tyroksiini (T4). In ka badan 99% oo ka mid ah laba steroids in dhiig ku wareegaya foomka borotiinada gaadiidka la xidhiidha. boqolkiiba ka yar hal waa qaab lacag la'aan ah. heerarka steroid furan in dadka intooda badan waa la isku xidhan la dawladda functional ah qanjirka thyroid.

guryaha tyroksiini

Hormone T4 (free) fududeeyaa qaanuunka ee koritaanka iyo horumarka caadiga ah, xaqiijinta dayactirka ah ee heerkulka jidhka, Kuna dayactirka dhicin kulaylka. Xarunta waxay leedahay saamayn ku dhammaan marxaladaha-shiid carbohydrate, in qayb ka - on vitamin iyo egyahay shiid. Hormone T4 (free) waa qayb muhiim ah oo ka horumarinta utero iyo muddooyinka dhalaanka. fiirsashada waxay muujinaysaa xaaladda caafimaad ee xaaladda thyroid ka, sida isbeddelka heerka guud ee tyroksiini waxa keeni laga yaabaa by rabshooyin in hawshu qanjirka thyroid ama isbedelka ku dhacay tirada borotiinada gaadiidka. Inta lagu jiro maalintii, content ugu badan ee steroid waxaa ka go'an ka 8 ilaa 12 saacadood, iyo ugu yaraan - 23 iyo 3. Sanadkan gudihiisa, heerka ugu sareeya 4 (free) Gaadha ka September si February, ugu hooseeya - xagaaga. In muddo dhalmada (inta lagu guda jiro uurka) fiirsashada tyroksiini kordhay, oo gaarey heerka ugu badnaan in ay si tartiib tartiib ah saddexda bilood ee saddexaad. Inta nolosha content thyroxin in dadka loo eegin jinsi weli yara joogto. heerarka hormone hoos u arkay ka dib intii afartan sannadood ah.

Waa maxay sheegi kartaa heerka tyroksiini?

Haddii T4 (free) si cad u kordhay, ka dibna loo arko xaqiijin ah ee tayroodh. fiirsashada hoos u muujinaysaa hypothyroidism. madaxbanaanida ee content ee steroid ee tyroksiini globulin ku qabanaya waxay suuro gelineysaa in ay u isticmaalaan sida tijaabo lagu kalsoonaan karo cudur-aqoonsiga. Tani waxay si gaar ah muhiim in xaaladaha waxaa weheliya isbeddel ah ee heerarka globulin tyroksiini-qabanaya. Kuwaas waxaa ka mid piller (afka), uurka, helitaanka antiandrogen ama estrogen. Isbedelada waa dabeecad iyo kuwa cabista dhaxlo si loo kordhiyo ama hoos u fiirsashada of globulin. Nalasoo dhiig T4 free talinayaa in nooca cudurka ee hypothyroidism sare sabab u heley in heerka hypothalamo-pituitary ee. Xaaladdan oo kale content TTG aysan waxba ka beddelin ama kordho. Sida caadiga ah, heerarka sare ee tyroksiini noqon kartaa sabab u ah heerka sare ee bilirubin serum, cayilka, iyo sidoo kale iska fur ah, marka baaritaanka dhiigga doonaan. 4 (free) aysan waxba ka beddelin cudurro daran hawlaha non-thyroid. Heerka guud ee tyroksiini hoos u dhici doono.

Diyaarinta imtixaanka shaybaarka

Hal bil ka hor dhiig uga reebay maamulka hormoonada (haddii ay jiraan tilmaamo gaar ah endocrinologist). Waayo, laba ama saddex maalmood in ay joojiyaan isticmaalka falanqaynta daroogada iodine-ka kooban. Dhiiga waa in ka hor inta aan waxbarashada shucaaca la isticmaalayo wakiilada la barbardhigo noqotay. Habeeynimadii of siiyo dhiig waa in ay iska ilaaliyaan dhaqdhaqaaqa jirka, la baabi'iyo xaalado walaac. Ka hor inta aan daraasadda, intii nus saac ah, waa in aad is dejisaan, keeni neefsashada si caadi ah. Falanqaynta lagu sameeyaa calool madhan. Iyada oo cuntada ee la soo dhaafay waa in ay ahaadaan aan ka yarayn siddeed saacadood (laakiin doorbidayaa 12 saacadood). Lama oggola in la cabbo qaxwada, shaaha ama casiir. biyo oo keliya karaan.

heerarka hoos tyroksiini

4 (free) (ragga iyo dumarka caadiga ah - 9-19 pmol / l) waa la dhimi karaa in muddada postoperative, marka hypothyroidism sare (caabuq pituitary ee, tireotropinome, syndrome, Sheehan). Yaraynta fiirsashada waxa uu sidoo kale xusay in ku saleysan anabolics soo dhaweynta, thyreostatics, daroogada anticonvulsant, diyaarinta lithium. heerka tyroksiini hoos marka la isticmaalayo piller, octreotide, metadon, clofibrate. Sababaha macquulka ah ayaa sidoo kale waxaa ka mid ah cunto la qadar kooban oo protein, deficiency iodine, isticmaalka heroin, gaadhista keeni. 4 (free) waa la dhimi karaa iyadoo jaamacadda (hypothalamus dareemayaasha maskaxda), helay, lagu dhasho ee hypothyroidism (iyada oo resection ballaaran oo ka mid ah buro iyo thyroid, Graves, shalalka, goiter-gud).

Kordhinta uruureen

Heerka hormone sida T4 (free) (ragga iyo dumarka aan kor ku tilmaamay mid caadi ah) waa la kordhin karaa marka goiter sun ah, tayroodh TSH-madax-bannaan, cayilka. Kordhinta fiirsashada arkay on asalka ah ee syndrome nephrotic, therapy heparin. Sababaha sidoo kale waxaa ka mid ah choriocarcinoma, soo dhaweynta ee tyroksiini ah oo ku saleysan hypothyroidism, isbedel post-natal hawlaha qanjirka thyroid ka, cudur beerka ku gaamuuray. 4 (free) la Qolol karaa steroids syndrome iska caabin thyroid, hyperthyroxinemia dizalbunemicheskoy hidde, dhigayaa, oo iska xanaajin fiirsashada hoos globulin tiroksinsyazyvayuschego ah.

Tyroksiini iyo uurka

hormoonnada Hunguriga ku lug ku dhowaad habka kasta ee jirka. Sida kor ku xusan, xeryahooda ee nidaaminaya-shiid, saamayn waxqabad ee steroids kale. cudurada thyroid waxaa la socon kara by labada koror iyo hoos u dhac in hawlihiisa. Muhiimad gaar ah xadgudub ku ah hawlaha xubnaha leedahay inta lagu jiro dhalista ah. Isbeddelka ee gobolka functional ah qanjirka thyroid saameeyaa koorsada ee uurka, iyada oo qof, iyo natiijada xaalada dhashay. Marar dhif ah vynashivanie maraa marka muujiyay heley hormoonada jidhka. Cudurrada noocan ah, sida caadiga ah, waxay keeni in cillad taranka, dhalmo la'aan. Inta badan laga helay inta lagu guda jiro uurka goiter (koror ee dabiiciga ah thyroid waajihi) la ilaalinta euthyrosis, iyo sidoo kale Graves, shalalka, oo iska xanaajin isbeddel ah ee ku soo jeeda oo hormoon ah. Muddo dhalmada waxa lagu gartaa isbeddel ah ee gobolka functional of qanjirka.

talooyinka

Si aad si sax ah u fasiro natiijooyinka baaritaannada shaybaarka inta aad uurka leedahay waa in ay tixgeliyaan qaar ka mid ah dhibcood. Determination of T3 total iyo T4 ma aha wargelin ah. Tan waxa u sabab xaqiiqada ah in inta lagu guda jiro uurka, ay fiirsashada waxaa kordhay badh. Marka baadhitaanka heerka tyroksiini furan ay fiirsashada waa in la go'aamiyey in lala content TTG. Tyroksiini xoogaa kor u kacay in ku saabsan 2% ka mid ah haweenka uurka leh. In qeybtii hore ee xilliga caadiga ah dhalmada calaamadeeyay hoos TTG (qiyaastii 20-30% bukaannada qaba singletons iyo dhammaan xaaladaha uurka badan). In daaweynta T4 tayroodh baaritaan kaliya (free). heerka tyroksiini furan ku jira marxaladaha dambe laga yaabaa in yar hoos u. Sayidka fiirsashada TSH waa sidoodii ee heerka caadiga ah.